Clinical trials: Glucose Control
Malnutrition, Diabetes
Efficacy of Zinc Fortified Fermented Wheat Flour
Zinc is a pivotal micronutrient that participates in numerous essential metabolic pathways within the human body. Its multifaceted role makes the manifestations of zinc deficiency remarkably nonspecific and age-dependent.
- Conditions
- Malnutrition, Diabetes, Inflammation, Conjunctivitis
- Trial name
- EZAFFAW (NCT06092515)
- Testing
- Fermented High Zinc Wheat Flour Flatbread, Unfermented High Zinc Wheat Flour Flatbread, Post-Harvest Fortified Whole Wheat Flour Flatbread
- Where
- Pakistan
- Volunteers
- 1,044 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Healthy Participants, Type 2 Diabetes
A Study to Investigate Multiple Ascending Doses of AZD5004 in Healthy Japanese Participants and Participants With Type 2 Diabetes Mellitus
This Phase I study will gather important information on the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD5004 in both healthy Japanese participants and Japanese participants with T2DM.
- Trial name
- NCT06703658
- Testing
- AZD5004(Part A), AZD5004(Part B)
- Where
- Japan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Type 1 Diabetes
Role of Pregnancy Related Hormones in Lowering the Insulin Requirement in Pregnant Women With Type 1 Diabetes
This is a randomized, double-masked, placebo-controlled, single-center study to evaluate stimulated C-peptide secretion after exogenous administration of mild immunosuppression and growth-promoting factors to women with…
- Trial name
- NCT01265017
- Testing
- Estradiol, medroxyprogesterone, hydrocortisone, GH
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sansum Diabetes Research Institute
Frozen Shoulder
Exploring the Link Between Menopause, Glucose Control, and Frozen Shoulder in Women
Background Frozen shoulder (FS) is a common condition and affects how the shoulder moves, making it very stiff and sore. The shoulder joint becomes inflamed and tightened due to scarring in the joint called fibrosis.
- Trial name
- MENO-FROST (NCT07603089)
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Obesity, Dapagliflozin Adverse Reaction
The Effect of Dapagliflozin on Weight Loss in Obese Adults Without Diabetes
The goal of this clinical trial is to examine the effectiveness of a drug named dapagliflozin (tested drug) on weight loss in young adults aged between 18 and 40 years with obesity who are not diagnosed with diabetes.
- Conditions
- Obesity, Dapagliflozin Adverse Reaction, Weight Loss, Effect of Drug
- Trial name
- DAPA-ANDO (NCT06000462)
- Testing
- Dapagliflozin 10mg Tab, Metformin 1000 mg (ttd)
- Where
- Oman
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Oman Ministry of Health
Diabetes Mellitus
A Study to Determine the Absorption of Peroral Insulin in Dextran Matrix (ORA3)
A pharmacokinetic study on the absorption of perorally delivered insulin in dextran matrix after single dose administration.
- Trial name
- ORA3 (NCT01114750)
- Where
- Sweden
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Bows Pharmaceuticals AG
Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2
A Study to Compare the Effect on Heart Rhythm of 3 Days of GSK189075, Placebo, or Moxifloxacin in Healthy Adults
This study assesses for change in heart rhythm of healthy volunteers taking GSK189075 for 3 days at a normal dose and a higher than normal dose compared to placebo or to a single dose of moxifloxacin.
- Trial name
- NCT00532610
- Testing
- GSK189075
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy, Diabetes
Meta-analysis of Oats for Diabetes Prevention and Management
Oats are a commonly consumed source of viscous soluble fibre, which has an established role in cardiovascular disease risk management including in cholesterol and glycemic control.
- Conditions
- Healthy, Diabetes, Metabolic Syndrome, Overweight and Obesity
- Trial name
- NCT04631913
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes, Cardiovascular Risk
The Effects of Soy Protein and Isoflavones on Glycemic Control, Insulin Sensitivity and Cardiovascular Risk Factors
The investigators propose to perform a double-blind, randomized placebo-controlled trial to examine the hypothesis that soy protein with isoflavones could improve glycemic control, insulin sensitivity and decrease cardiovascular…
- Trial name
- NCT00856882
- Testing
- soy protein, isoflavones, milk protein
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Hunger
Eating Disinhibition and Vagal Tone and the Postprandial Response to Glycaemic Load
Reducing the glycaemic load (GL) of the diet may benefit appetite control but its utility is complicated by psychological influences on eating.
- Trial name
- NCT02827318
- Testing
- Isomaltulose, Glucose, Sweetened water
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Swansea University
Cholesterol; Lipidosis
Can Mindful Eating Improve Cholesterol and Glucose Level
This study aims to explore the effectiveness of mindful eating and its effect on cholesterol and glucose level. The participants will be required to get tested for their fasting total cholesterol and blood glucose level for two…
- Trial name
- NCT04833595
- Testing
- Mindfulness practice
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monash University Malaysia
Gastroenteritis, Dehydration
Study Investigating the Use of Intravenous Fluids With Dextrose for Dehydrated Children
Infants and young children often become infected with gastroenteritis leading to vomiting and diarrhea. This can lead to dehydration, one of the most common complaints in the Pediatric Emergency Department.
- Trial name
- NCT01343758
- Testing
- 5% dextrose in normal saline
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Type 1 Diabetes, Type 1 Diabetes Mellitus
Evaluating Glucose Control Using a Next-Generation AID Algorithm in Individuals With T1D
Feasibility study to evaluate the safety and feasibility of Omnipod automated insulin delivery algorithms in individuals with type 1 diabetes.
- Conditions
- Type 1 Diabetes, Type 1 Diabetes Mellitus, Diabetes (DM)
- Trial name
- EVOLUTIONT1D (NCT07593625)
- Testing
- Omnipod M System, Omnipod S
- Where
- New Zealand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Insulet Corporation
Type 2 Diabetes, Metabolic Health
Effect of Prebiotics in Saudi Adults With Type 2 Diabetes
This study will explore how a natural food ingredient called oligofructose affects blood glucose levels, lipid profiles, inflammation biomarkers, and gut bacteria in Saudi adults with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Metabolic Health, Inflammation, Gut Microbiome
- Trial name
- NCT07464691
- Testing
- oligofructose
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Princess Nourah Bint Abdulrahman University
Metabolic Syndrome
Calorie Restricted Diet and Exercise
Calorie-restricted(CR) diet and exercise were effective to reduce Metabolic syndrome(MetS), however, its effect on knee functions for MetS patients with degenerate meniscus lesions(DMLs) was still poorly investigated.
- Trial name
- NCT05092178
- Testing
- calorie restricted diet and exercise, exercise alone
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Jingzhou
T2DM (Type 2 Diabetes Mellitus)
Single Escalating Dose Study Of HSK7653 In Healthy Subjects
To evaluate the safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of single dose of HSK7653 tablets in healthy adult subjects, and to identify the metabolites of HSK7653 in healthy adult subjects
- Trial name
- NCT05983289
- Testing
- HSK7653
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Type1diabetes
Metabolic Profiling of Type 1 Diabetes Mellitus in Children and Adolescents
The aim of this study was to look for discriminating variation in the concentrations of small-molecule metabolites in the plasma of T1DM children compared with non-diabetic matched controls using proton nuclear magnetic resonance…
- Trial name
- T1DM (NCT03014908)
- Testing
- Blood sampling
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Obesity
Involvement of the Gut Microbiota-brain Cross-talk in the Loss of Eating Control
Overweight and obesity are increasingly prevalent worldwide. These bodyweight disorders are closely related to deficiencies in the control of food intake.
- Trial name
- GMBTalk-Food (NCT05646901)
- Where
- Spain
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Brain Activity, Appetite
Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol
The objectives of the research are to assess the effects of increased protein and fiber intake at breakfast on neural activation in brain regions associated with appetitive drive and reward-driven eating, measures of subjective…
- Conditions
- Brain Activity, Appetite, Ingestive Behavior, Glucose Control
- Trial name
- PFB (NCT02169245)
- Testing
- Dietary control of protein and fiber intake at breakfast
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Type 1 Diabetes
A Study to Assess the Effects of CT-868 Treatment on Glucose Homeostasis in Participants with Type 1 Diabetes
This study will be conducted primarily to evaluate the effects of CT-868 on glucose homeostasis in participants with Type 1 Diabetes Mellitus.
- Trial name
- NCT05794581
- Testing
- CT-868, Victoza
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Carmot Therapeutics, Inc.
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