Clinical trials: Glucose Excursion
Cystic Fibrosis, Glucose Metabolism Disorders
The Relationship Between Diet and Glycemic Response and Inflammatory Markers in Children With Cystic Fibrosis
The aim of this study is to determine the relationship between diets of children with cystic fibrosis and glycemic responses and some inflammatory markers.
- Trial name
- NCT05748444
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- büşra başpınar
Type 2 Diabetes Mellitus
A Study of MK-0893 on Glucagon-Induced Glycemic Excursion in Healthy Male Participants Following Intravenous Administration of Glucagon, Sandostatine® and Insulin (MK-0893-002)
This is a study to assess the pharmacokinetics, safety, and tolerability of sequential single oral doses of MK-8093 10 mg, 40 mg, 200 mg, or placebo to MK-8093 (Part 1) depending on treatment assignment in young healthy male…
- Trial name
- NCT02012166
- Testing
- MK-0893 10 mg, MK-0893 40 mg, MK-0893 200 mg
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Insulin Resistance
Impact of Starch Digestibility on Glycemic Variability and Control, Cardiometabolic and Inflammatory Profiles, Microbiota and Intestinal Health in Subjects With Insulin Resistance
To study the potential impact of a diet rich in both Slowly Digestible Starch (SDS) and Resistant Starch (RS), we propose a 2-month nutritional intervention study in which we will study the evolution of carbohydrate variability…
- Trial name
- GLYMICARE (NCT07408479)
- Testing
- Balanced diet high in Slowly Digestible Starch and Resistant Starch, Balanced diet low in Slowly Digestible Starch and Resistant Starch
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Type 1 Diabetes Mellitus
Comparison of FiAsp and Aspart During Postprandial Exercise in Adults With Type 1 Diabetes
Hypoglycemia is the main barrier for physical activity practice of patients with type 1 diabetes (T1D). For postprandial exercise, anticipation with meal insulin bolus reduction is the recommended method to reduce…
- Trial name
- NCT03659799
- Testing
- Insulin FiAsp, Insulin Aspart, 60-minutes postprandial exercise
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type2 Diabetes
Cardio-metabolic and Inflammatory Impact of Starch Digestibility in Type 2 Diabetic Patients
This is a monocentric, randomized, single-blind and controlled study with a parallel design (2 arms). The research hypothesis is that the diet high in Slow Digestible Starch (SDS) content (H-SDS) will lower the daylong glycemic…
- Trial name
- NCT03847701
- Testing
- Balanced diet high in Slowly Digestible Starch, Balanced diet low in Slowly Digestible Starch
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Mondelēz International, Inc.
Diabetes Mellitus
Effects of Acarbose Versus Glibenclamide on MAGE and Oxidative Stress in Patients With Type 2 DM
To compare effect of acarbose versus glibenclamide treatment on mean amplitude of glyclemic excursion and oxidative stress in diabetes individuals who failed to control their glucose by metformin therapy alone
- Trial name
- NCT00417729
- Testing
- Acarbose
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Taichung Veterans General Hospital
Diabetes Mellitus
Impact of Pantoprazole on 24-H Glycemic Control and on Post-prandial Glucose Excursion in Patients With Type 2 Diabetes
The purpose of this study is to demonstrate the immediate impact of pantoprazole on 24-H glycemic control and on post-prandial glucose excursion in patients with type 2 diabetes.If our data support the previous animal…
- Trial name
- NCT02345239
- Testing
- Pantoprazole
- Volunteers
- 14 people
- Sponsor
- Dr. Waheed Rehman
Type 2 Diabetes
Glycemic Excursion Minimization (GEM) to Outshine Health Disparities
The purpose of this study is to see if the GEM intervention is acceptable and helpful to Black adults with type 2 diabetes. The GEM intervention (coaching to reduce carbohydrate intake and increase physical activity after meals…
- Trial name
- GEM (NCT06236581)
- Testing
- GEM Intervention
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Catherine Davis
Type 1 Diabetes Mellitus
Detemir: Role in Type 1 Diabetes
Study of blood sugars in the children with Type 1 Diabetes Mellitus (T1DM), who are given insulin detemir and a rapid acting insulin (aspart).
- Trial name
- NCT00564395
- Testing
- Insulin Detemir mixed with RAI injection, Insulin Detemir and RAI injection
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Montefiore Medical Center
Fasting Glucose, Glucose Excursion
Dapagliflozin in Type 1 Diabetes
Dapagliflozin is a highly selective, reversible and potent inhibitor of the sodium-glucose-linked Transporter 2 (SGLT2), which was successfully investigated for its use as a treatment option in type 2 diabetes mellitus.
- Conditions
- Fasting Glucose, Glucose Excursion, Glycemic Control
- Trial name
- DapaT1DM (NCT02211742)
- Testing
- Dapagliflozin
- Where
- Austria
- Volunteers
- 12 people
- Sponsor
- Medical University Innsbruck
PreDiabetes
CGM Plus GEM in Prediabetes
This study is designed to look into the effect of a lifestyle management guide called GEM (Glycemic Excursion Minimization) alongside continuous glucose monitoring (CGM) and an activity monitor (FitBit) and the effect this can…
- Trial name
- IMPEDE (NCT05580978)
- Testing
- GEM, Routine Care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Colorado, Denver
Sedentary Behavior
Interrupting Sitting Time During Postprandial State
The literature has shown that interrupting sitting time with frequent physical activities (e.g., cycling on a stationary bike for 3 minutes every 30 minutes of sitting) is effective for decreasing blood sugar levels.
- Trial name
- NCT04590729
- Testing
- 3-min Exercise Per 30 Min, 3-min Exercise Per 15 Min
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Franklin Pierce University
Type 2 Diabetes
Vitamin D Inadequacy on Postprandial Glucose in Type 2 Diabetes Mellitus
Vitamin D deficiency is associated with an unfavorable metabolic profile in several observational studies. However, the influences of vitamin D concentrations on postprandial glucose in type 2 diabetes (DM) are less studied.
- Trial name
- NCT01488916
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Type 1 Diabetes, Hypoglycemia
Effect of Continuous Glucose Monitoring on Course of Glucose in Type 1 Diabetes
The objective of this cross over study is to access if continuous glucose monitoring (CGMS) with a real time feed back and hypoglycemic as well as hyperglycemic glucose alerts vs.
- Trial name
- NCT00467688
- Testing
- Real time access to current glucose values during CGMS
- Where
- 2 sites in Germany
- Volunteers
- 50 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Type 2 Diabetes Mellitus
Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus
Investigate the acute effect of the steviol glycoside, rebaudioside A, on the glucose excursion during an oral glucose tolerance test in 30 patients with type 2 diabetes mellitus.
- Trial name
- AREBAG (NCT03510624)
- Testing
- Rebaudioside A
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Type 2 Diabetes Mellitus, Poor Glycemic Control
A Study for Sufficient Acarbose Decreased Glucose Excursion in Type 2 Diabetic Patients
This is a multicentre observational study to investigate the improvement in glucose fluctuation of sufficient acarbose therapy on type 2 diabetes patient with high blood glucose fluctuation
- Trial name
- FLAT (NCT03805191)
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Qilu Hospital of Shandong University
Diabetes Mellitus, Type 2
Effects of Nateglinide on Postprandial Glucose Excursion by Restoring Early Phase Insulin Secretion
A 3-week, multi-center, open-label, randomized, active-control, parallel-group study to compare effects of Nateglinide and Acarbose on postprandial glucose fluctuation in Chinese drug-naive patients type 2 diabetes mellitus…
- Trial name
- NCT01030952
- Testing
- Nateglinide, Acarbose
- Where
- 3 sites in China
- Volunteers
- 103 people
- Sponsor
- Novartis Pharmaceuticals
Cystic Fibrosis-related Diabetes, Cystic Fibrosis
The Effect of Soluble Fiber to Reduce Post-prandial Glycemic Excursion in Adults With Cystic Fibrosis
With improved survival, the clinical spectrum of cystic fibrosis (CF), a complex multi systemic disease, continue to evolve. A major emerging complication is CF related diabetes (CFRD) which is occurring in 40-50% of adults.
- Trial name
- SOFI (NCT02810691)
- Testing
- Soluble fiber supplementation
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Local Registration Trial in China Humalog Mix 50
The primary objective of this study is to compare the 2-hour PPBG excursion following a standard test meal in insulin-requiring diabetic patients treated twice daily with human insulin mix 50/50, versus the 2-hour PPBG excursion…
- Trial name
- NCT00191581
- Testing
- Humalog Mix 50, Human Insulin Mix 50:50
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes
Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification
A Randomized Control Trial (RCT) with 1:1 randomization of adults newly diagnosed with type 2 diabetes (T2D) to Routine Care (RC) and RC + Glycemic Excursion Minimization (RC+GEM); a program that provides RC in addition to…
- Trial name
- GEM (NCT05766735)
- Testing
- Routine Care + Glycemic Excursion Minimization (RC+GEM), Routine Care (RC)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Chiara Fabris, PhD