Clinical trials: Glucose Intolerance During Pregnancy
Polycystic Ovary Syndrome, Insulin Resistance
Insulin Resistance Before and During Pregnancy in Women With Polycystic Ovary Syndrome
The polycystic ovary syndrome (PCOS) affects about 10% of reproductive-age women. Women with PCOS are at a higher risk of gestational diabetes, which may lead to more pregnancy complications.
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Insulin Sensitivity, Obesity
- Trial name
- NCT01475565
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Virginia Commonwealth University
Glucose Tolerance Impaired in Pregnancy
Women With Minor Degrees of Glucose Intolerance and the Postpartum Glucose Tolerance Test
The aim of this study is to offer a 75g postpartum glucose tolerance test to women with minor degrees of glucose intolerance and to assess if these women are significantly different from women who were diagnosed as GDM…
- Trial name
- NCT03623412
- Testing
- 75g oral glucose tolerance test, 75g GTT
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Pregnancy Related, Stress, Psychological
Maternal Emotions and Diet in Pregnancy
This study seeks to understand how a mother's emotional state in pregnancy influences her biological response to food intake.
- Conditions
- Pregnancy Related, Stress, Psychological, Glucose Intolerance During Pregnancy
- Trial name
- PEDIMet (NCT03278392)
- Testing
- Trier Social Stress Test
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Diabetes, Gestational, Pregnancy Complications
Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes
Pregnant women aged 18-45 with gestational diabetes (GDM) will take part in this study. We want to see how two different insulin treatments affect their blood sugar after they eat.
- Conditions
- Diabetes, Gestational, Pregnancy Complications, Glucose Metabolism Disorders, Glucose Intolerance During Pregnancy
- Trial name
- INHALE-GDM (NCT06535789)
- Testing
- Inhaled Technosphere Insulin
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Jaeb Center for Health Research
Diabetes, Gestational, Dietary Modification
Dietary Management of Gestational Diabetes
eMOM is a randomized, controlled trial to compare the effects of two different dietary interventions during pregnancy. The comparison is based on tissue glucose content (using continuous glucose monitoring system) in pregnant…
- Conditions
- Diabetes, Gestational, Dietary Modification, Glucose Intolerance During Pregnancy, Body Composition
- Trial name
- eMOM (NCT03681054)
- Testing
- Carbohydrate restricted diet, Plant-protein based diet
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Gestational Diabetes, Inflammation
Effect of Very Low Carbohydrate Diet on Glycemic, Metabolic, Glycated and Inflammatory Markers in Gestational Diabetes Mellitus
Uncontrolled Gestational Diabetes Mellitus may leads to maternal and fetal complications. These complications can be avoided by adopting the dietary modifications along with medications.
- Conditions
- Gestational Diabetes, Inflammation, Metabolic Syndrome, Glucose Intolerance During Pregnancy
- Trial name
- NCT05305352
- Testing
- Very low carbohydrate dietary intervention
- Where
- Pakistan
- Sponsor
- Khyber Medical University Peshawar
Gestational Diabetes, PreDiabetes
Maternal Health Diabetes Prevention Study
The aim of this project is to use the Exploration, Preparation, Implementation, Sustainment (EPIS) framework to collect pilot data on the implementation of a Diabetes Prevention Program-like intervention in the Women, Infants…
- Conditions
- Gestational Diabetes, PreDiabetes, Hyperglycemia, Glucose Intolerance During Pregnancy
- Trial name
- NCT05343494
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tulane University
Pregnancy Related, Stress, Psychological
Emotion-Diet Interactions in Pregnancy
This study will investigate how maternal emotional state following a controlled stress exposure in pregnancy influences blood glucose and insulin levels after eating a standardized meal, and whether the effects of emotional state…
- Conditions
- Pregnancy Related, Stress, Psychological, Glucose Intolerance During Pregnancy, Emotional Stress
- Trial name
- PREDIP (NCT04430439)
- Testing
- Psychosocial stress, Control non-stress
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Obesity, Gestational Diabetes
Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics
The primary objective of the STRIVE study is to compare two implementation strategies for Diabetes Prevention Program delivery: an in-person health coach strategy (standard 24 in-person sessions at WIC clinics) vs.
- Conditions
- Obesity, Gestational Diabetes, Lifestyle, Healthy, Glucose Intolerance During Pregnancy
- Trial name
- STRIVE (NCT06116149)
- Testing
- In-person health coach delivery of the GLB, Technology-assisted health coach delivery of the GLB
- Where
- United States
- Volunteers
- 722 people, healthy volunteers welcome
- Sponsor
- Tulane University
Glucose Intolerance, Pregnancy
Probiotics (Lactobacillus Rhamnosus) in Reducing Glucose Intolerance During and After Pregnancy
Introduction: The overall aim of the study is to assess the efficacy of Lactobacillus Rhamnosus in reducing glucose intolerance during and after pregnancy.
- Trial name
- GRIP (NCT01436448)
- Testing
- Probiotics Lactobacillus Rhamnosus
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Aga Khan University
Gestational Diabetes Mellitus
Long Term Effects of Gestational Diabetes Mellitus in a Population of Parous Women
The primary goal of this proposed research deals with estimating the risk of developing type 2 diabetes and metabolic syndrome in women with a history of GDM compared to women without a history of GDM.
- Trial name
- GDM (NCT01637727)
- Where
- Israel
- Volunteers
- 324 people
- Sponsor
- Shaare Zedek Medical Center
Diabetes, Gestational, Insulin Sensitivity
Glucose Monitoring During Threatening Preterm Birth in Patients With and Without Gestational Diabetes Mellitus
This study aims to show whether the hyperglycaemic phases following a treatment with glucocorticoids, as well as blood measurements correlated to high blood glucose levels and insulin resistance, vary significantly between…
- Conditions
- Diabetes, Gestational, Insulin Sensitivity, PreTerm Birth, Glucose Intolerance During Pregnancy
- Trial name
- NCT03007186
- Where
- Austria
- Volunteers
- 36 people
- Sponsor
- Medical University of Vienna
Gestational Diabetes, Glucose Intolerance During Pregnancy
Comparison of the Detection Rates of 50 Gr-100 Gr OGTT and 75 Gr OGTT That Require Medical Treatment of GDM
Both 50 gr OGTT-100 gr OGTT and 75 gr OGTT are used for detecting gestational diabetes mellitus. Two approaches are approved by obstetricians.
- Trial name
- NCT04585204
- Testing
- Oral glucose tolerance test
- Where
- Turkey (Türkiye)
- Volunteers
- 2,282 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Impaired Glucose Tolerance, Fetal Macrosomia
Treatment of Impaired Glucose Tolerance in Pregnancy
The purpose of this study is to evaluate if treatment (insulin or diet) of pregnant women with impaired glucose tolerance (75-g OGTT with a fasting P-gluc <7.0 mmol/l and 2 h P-gluc >10.0 and <12.2 mmol/l) close to normoglycemia…
- Trial name
- TIP (NCT00625781)
- Testing
- Insulin aspart and Insulin human (isophane)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Continuous Glucose Monitoring, Diabetes, Gestational
Early Pregnancy Lifestyle and Glucose Patterns: A Substudy of TOFFFY
The goal of this clinical trial is to examine how daily behavioral patterns in early pregnancy, including sleep, physical activity, and meal timing, influence continuous glucose dynamics and subsequent risk of gestational…
- Conditions
- Continuous Glucose Monitoring, Diabetes, Gestational, Diet During Pregnancy, Meal Time
- Trial name
- NCT07534670
- Testing
- Continuous glucose monitor (CGM), Wrist actigraphy device, AI-based dietary and meal timing logging mobile application
- Where
- Singapore
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Gestational Diabetes Mellitus (GDM), Glucose Intolerance During Pregnancy
Early Screening for Gestational Diabetes Mellitus in a Low Risk Population
This new feasibility pilot study aims to refine the design and protocols for a larger trial that will investigate the potential benefits of early oral glucose tolerance test (OGTT) screening in a population traditionally defined…
- Trial name
- EaGeR (NCT06704035)
- Testing
- Early OGTT Results Revealed
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy
Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes
The effects of consuming non-nutritive sweeteners (NNS) during pregnancy and lactation on infant obesity and cardiometabolic disease risk are not well understood.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy, Non-nutritive Sweeteners Consumption in Pregnancy and/or Lactation
- Trial name
- NCT06548828
- Testing
- NNS Restriction Intervention, Control Intervention
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- George Washington University
Gestational Diabetes Mellitus (GDM)
Screening for Dysglycemia During Postpartum Period in Women With GDM
Gestational diabetes mellitus (GDM) is one of the most common clinical conditions in pregnancy, with an increasing incidence due to the rise in overweight women and the postponement of motherhood.
- Trial name
- NCT07489456
- Testing
- Whatsapp message
- Where
- Brazil
- Volunteers
- 182 people
- Sponsor
- University of Sao Paulo General Hospital
Glucose Intolerance During Pregnancy
Effects of Vitamin D and Prebiotic Supplementation on Glucose Control During Pregnancy
The goal of this randomized, double-blind, placebo-controlled study included pregnant women at high risk of GDM at 6-15 weeks of gestation is to investigate whether supplementation with vitamin D (1600 IU per day) or prebiotics…
- Trial name
- NCT06553729
- Testing
- Vitamin D3, Prebiotics
- Where
- 2 sites in China
- Volunteers
- 500 people
- Sponsor
- Huazhong University of Science and Technology
Gestational Diabetes, Glucose Tolerance Impaired in Pregnancy
Food Product for Management of Gestational Diabetes
The goal of this pilot open pre-post clinical trial is to test effects of a wholegrain product in patients with newly diagnosed gestational diabetes.
- Conditions
- Gestational Diabetes, Glucose Tolerance Impaired in Pregnancy, Glucose Tolerance Impaired, Pregnancy Related
- Trial name
- NCT05917808
- Testing
- Ready-to-eat wholegrain porridge
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Stoffwechselzentrum Rhein - Pfalz