Clinical trials: Glucose Metabolism
Cardiovascular Disease, Diabetes
Care China-Diabetes
This multicenter, prospective, observational registry will assess efficacy and safety outcomes associated with percutaneous coronary intervention (PCI) with implantation of the CYPHER Select™+ Sirolimus-eluting Coronary Stents in…
- Trial name
- NCT00938119
- Where
- 46 sites in China
- Volunteers
- 1,603 people
- Sponsor
- Johnson & Johnson Medical, China
Type 1 Diabetes Mellitus, Adolescent Behavior
Using an mHealth App to Transition Care of Type-1 Diabetes From Parents to Teens
Type 1 diabetes (T1D) afflicts approximately 154,000 people under the age of 20. Most people with T1D are diagnosed at a young age; their parents have to manage their child's condition.
- Conditions
- Type 1 Diabetes Mellitus, Adolescent Behavior, Parent-Child Relations, Communication
- Trial name
- NCT03436628
- Testing
- MyT1DHero
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Diabetes Mellitus, Type 2, Hypertension
Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)
MK-8835-042 (B1521004) is designed to assess the safety and efficacy of an investigational drug, ertugliflozin (MK-8835, PF-04971729), in participants with type 2 diabetes and hypertension.
- Trial name
- NCT01096667
- Testing
- Ertugliflozin 1 mg, Ertugliflozin 5 mg, Ertugliflozin 25 mg
- Volunteers
- 194 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus
Evaluating the Effects of Kombucha as a Hyperglycemic Therapeutic Agent Within Diabetic Human Subjects
This study's primary objective is to determine the ability of Kombucha to impact blood sugar levels in patients with diabetes mellitus type II.
- Trial name
- NCT04107207
- Testing
- Ginger Kombucha, Ginger Water
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Diabetes Mellitus, Type 2
Lifestyle Intervention for Adults With Diabetes
Physical activity is the cornerstone of good diabetes management, and yet effective physical activity intervention is not available.
- Trial name
- NCT02699307
- Testing
- Counseling
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Michigan
Diabetes Mellitus, Type 2
Effects of a Small Protein and Lipid Preload on Glucose Tolerance in Subjects With Impaired Glucose Homeostasis
The purpose of this study is: to measure the size of the effect on glucose tolerance of a small mixed protein and lipid meal given as a pre-load in individuals with different glucose tolerance status to investigate the underlying…
- Trial name
- NCT02342834
- Testing
- Small mixed protein and lipid meal
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Diabetes Mellitus, Type 1
Islet Cell Transplants for Diabetes
The purpose of this study is to test the safety and efficacy of islet cell transplants for the treatment of type 1 diabetes mellitus.
- Trial name
- NCT00303134
- Testing
- Islet Cell Transplantation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Weill Medical College of Cornell University
Type 1 Diabetes
Hybrid Closed-Loop Hotel Studies With Medtronic PID Controller
The primary objective of this study is to evaluate the safety and efficacy of the Medtronic hybrid closed-loop (HCL) system utilizing the proportional-integral-derivative algorithm with insulin feedback (PID-IFB) optimized to…
- Trial name
- NCT02280863
- Testing
- Medtronic Hybrid Closed-loop System - Android Platform, Medtronic Hybrid Closed-loop Integrated System
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stanford University
Type 2 Diabetes Mellitus
Effect of Green Tea Extract on Arterial Stiffness in Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) has become the epidemic of the XXI century. This chronic disease is also highly prevalent and primarily associated with an increased cardiovascular mortality and morbidity due to micro and…
- Trial name
- NCT02627898
- Testing
- green tea extract
- Volunteers
- 24 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Diabetic Kidney Disease, Diabetes Mellitus, Type 2
Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy
The study is focused on the possible improving effect of N-acetylcysteine on nephropathy of type-2 diabetic patients. Study design: Prospective clinical based study.
- Conditions
- Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Diabetic Nephropathies
- Trial name
- (NAC) (NCT04531163)
- Testing
- N Acetylcysteine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Diabetes Mellitus, Type 1
To Examine the Lung When People With Diabetes Take an Inhaled Form of Insulin, Compared to Subcutaneous Insulin.
To examine the lung when people with diabetes take an inhaled form of insulin, compared to subcutaneous insulin.
- Trial name
- NCT00143104
- Testing
- Inhaled insulin
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Pfizer
Diabetes
EFFECTIVENESS OF A TRIPLE NUTRITIONAL INTERVENTION AND PHYSICAL IN PREDIABETIC PATIENRS
Diabetes represents a substantial burden on health care systems. People with prediabetes IGT (impaired glucose tolerance) or IFG (impaired fasting glucose) are at high risk of developing diabetes, and up to 50% progress to…
- Trial name
- NCT06820775
- Testing
- A TRIPLE INTERVENTION NUTRITION AND PHYSICAL ACTIVITY
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Bioaraba Health Research Institute
Oncology, Metabolic Disease
Nutritional Safety and Metabolic Benefits of Oncometabolic Surgery for Obese Gastric Cancer Patients
The metabolic effect of oncometabolic surgery (long limb Roux-en Y reconstruction) for early gastric cancer patients has been revealed in a few pilot studies.
- Conditions
- Oncology, Metabolic Disease, Gastric Cancer
- Trial name
- ONCOMETAB (NCT03067012)
- Testing
- Oncometabolic reconstruction
- Volunteers
- 20 people
- Sponsor
- Seoul National University Bundang Hospital
First Episose Psychosis, Metabolic Disease
The ATP Project (Antipsychotic-TEP-Psychosis)
The goal of this observational study is to the early impacts of psychosis and antipsychotic medications on brain metabolism in young adults recently diagnosed with a first episode of psychosis.
- Conditions
- First Episose Psychosis, Metabolic Disease, Psychosis; Episode
- Trial name
- ATP (NCT06651112)
- Testing
- Antipsychotic drugs
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Université de Sherbrooke
Diabetes Mellitus, Diabetes Mellitus, Type 1
An Open-Label, FIH Study Evaluating the Safety and Tolerability of VCTX210A Combination Product in Subjects With T1D
This is an open-label, multicenter, Phase 1 study evaluating the safety and tolerability of VCTX210A combination product in patients with T1D
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- NCT05210530
- Testing
- VCTX210A unit
- Where
- 3 sites in Canada
- Volunteers
- 7 people
- Sponsor
- CRISPR Therapeutics AG
Diabetes, Inflammation
Vascular Risk Progression in Normal and Diabetic Control Subjects.
The purpose of this study is to look at the progression of cardiovascular disease (CVD) in normal control individuals and in patients with controlled diabetes.
- Trial name
- NCT00579228
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Diabetes Mellitus
Clinical Effects of Pulsatile Insulin Delivery on Cognitive Function- Phase 1
To determine if restoring normal metabolic function in patients with either Type I or Type II Diabetes can improve overall cognitive function.
- Trial name
- NCT00228865
- Testing
- Pulsatile IV insulin therapy, Effects of Pulsatile IV Insulin on Cognitive functions
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Florida Atlantic University
Peri-implantitis, Dental Implants
The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices
This cross-sectional study evaluates the impact of systemic risk factors, including diabetes mellitus, smoking, cardiovascular disease, and osteoporosis, on peri-implant health status and clinical indices.
- Conditions
- Peri-implantitis, Dental Implants, Peri-implant Mucositis
- Trial name
- NCT07530211
- Testing
- Clinical and Radiographic Periodontal Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Inonu University
Hypo-unawareness, Type 1 Diabetes Mellitus
Effect of a Medium Chain Triglyceride Supplemented Diet on Cognitive Function and Brain Activation in Type 1 Diabetes.
Insulin treatment often causes the blood glucose levels to fall too low (hypoglycemia). Hypoglycemia can be associated with confusion and disorientation as well as other symptoms such as palpitations, sweating and tremors.
- Trial name
- NCT01315171
- Testing
- Medium chain triglycerides
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Yale University
Type II Diabetes in Subjects BMI 27 to 32
Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes Versus Best Medical Treatment
Investigators aim to show that Roux-en-Y Gastric Bypass (RYGB) is superior to best medical treatment in reaching well-defined treatment end points in Asian subjects of BMI 27-32 with type 2 Diabetes (DM2).
- Trial name
- NCT02041234
- Testing
- Roux-en-Y Gastric Bypass (RYGB), Incretin analogues, Xenical
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Khoo Teck Puat Hospital
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