Clinical trials: Glucose Metabolism
Diabetes Mellitus, Pulmonary Tuberculosis
Pulmonary Tuberculosis Patients With Diabetes Mellitus
The purpose of this study is to evaluate the effect of enhanced glycemic monitoring of diabetes upon diabetes glycaemic control during tuberculosis treatment in tuberculosis- diabetes patients.
- Trial name
- TANDEM (NCT02106039)
- Testing
- intensive monitoring
- Where
- 3 sites in Indonesia, Peru and 1 more
- Volunteers
- 350 people
- Sponsor
- Universitas Padjadjaran
Healthy, Type 1 Diabetes
Subcutaneous Administration of Lisofylline to Healthy Normal Subjects and Subjects With Type 1 Diabetes
Type 1 diabetes mellitus (T1DM) is an autoimmune disease. Autoimmune diseases happen when the immune system does not identify part of the body as belonging to it.
- Trial name
- NCT00896077
- Testing
- Lisofylline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DiaKine Therapeutics, Inc.
Acute Pancreatitis
Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics
The DREAM-ON study will investigate whether continuous glucose monitoring (CGM) is useful to predict risk for developing diabetes mellitus (DM) and pre-diabetes mellitus (PDM), the need for insulin therapy among those who develop…
- Trial name
- DREAM-ON (NCT06401577)
- Testing
- Dexcom Continuous Glucose Monitor (CGM)
- Where
- 13 sites in United States
- Volunteers
- 800 people
- Sponsor
- Milton S. Hershey Medical Center
Type 1 Diabetes, Hypoglycemia
Insulin Management for Exercise in Patients With Type 1 Diabetes
The purpose of this study is to compare the time spent in glucose target range (4.0-10.0 mmol/L) during exercise and in recovery using three different basal insulin management strategies for prolonged aerobic exercise: A) pump…
- Conditions
- Type 1 Diabetes, Hypoglycemia, Physical Activity
- Trial name
- NCT03130101
- Testing
- Change in their basal insulin rate
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- York University
Diabetes Mellitus, Type 2
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
This study is being done to look at the effect and safety of different doses of NNC0662-0419 in people living with type 2 diabetes when compared to placebo or semaglutide.
- Trial name
- NCT07415954
- Testing
- NNC0662-0419, Semaglutide
- Where
- 63 sites in United States, Croatia and 8 more
- Volunteers
- 270 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes
A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies
The purpose of this study is to identify and characterize patients with known Type 2 Diabetes Mellitus (T2DM) for possible participation in ongoing or future T2DM clinical studies, and to characterize trends in key concomitant…
- Trial name
- NCT07606066
- Testing
- Procedure: assessment
- Where
- 76 sites in United States, Brazil and 5 more
- Volunteers
- 2,150 people
- Sponsor
- AstraZeneca
Type 2 Diabetes
Provider-Initiated Regular Remote Interventions for Optimal Type 2 Diabetes Care
Patients with type 2 diabetes can attain superior disease outcomes if multiple therapy goals are simultaneously achieved and maintained.
- Trial name
- NCT01920256
- Testing
- Remote, personalized type 2 diabetes care., Usual Endocrine care.
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Dietary Habits, Gestational Diabetes
Dietary Intervention, Gestational Weight Gain and Gestational Diabetes.
The aim of this pilot study is to conduct a dietary intervention for overweight (body maas index BMI≥25) and obese (BMI≥30) pregnant women in two maternity care clinics and explore the effect of the intervention on gestational…
- Conditions
- Dietary Habits, Gestational Diabetes, Weight Gain, Overweight and Obesity
- Trial name
- NCT03191331
- Testing
- Dietary intervention
- Where
- 2 sites in Finland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Type 1 Diabetes
Effect of Hyperglycemia on Gastric Emptying Interactions With Pramlintide
To examine the influence of acute glycaemia (normoglycaemia and hyperglycaemia) on gastric emptying kinetics in patients with type 1 diabetes and non diabetic subjects when treated with subcutaneous (SC) injections of pramlintide.
- Trial name
- NCT00489645
- Testing
- pramlintide
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Type 2 Diabetes Mellitus (T2DM)
The Effect of Individualized Nursing Interventions on Glycemic Variability and Self-Management in Type 2 Diabetes
Type 2 diabetes is a chronic disease with an increasing prevalence worldwide and in our country. In managing type 2 diabetes, the primary goal in the nursing process is to ensure blood glucose stability.
- Trial name
- NCT06973395
- Testing
- Nursing interventions, education, and follow-up will be provided to Type 2 diabetes patients for blood glucose variability.
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ataturk University
Hypoglycemia
Lactate to Treat Hypoglycemia
Tight glucose control in intensive care has become a major concern, allowing a reduction in morbidity and mortality. However, its use is limited by the percentage of hypoglycemia which can have severe consequences on the brain.
- Trial name
- NCT01387477
- Testing
- Lactate, Glucose
- Where
- France
- Sponsor
- Institut d'Anesthesiologie des Alpes Maritimes
Diabetes
Artificial Pancreas in Latin America
The purpose of this study is to use closed-loop systems with the algorithms designed by the University of Virginia and by the Instituto Tecnologico de Buenos Aires (ITBA)/ Universidad Nacional de La Plata (UNLP)/ Universidad…
- Trial name
- NCT02994277
- Testing
- 1° Phase: UVa algorithm 2° Phase: ITBA/UNLP algorithm
- Volunteers
- 5 people
- Sponsor
- Hospital Italiano de Buenos Aires
Diabetes, Anesthesia, Local
Healing Process and Blood Sugar Level Following Local Anesthetic Infiltration With and Without Vasoconstrictor
Evaluating the healing of the extraction socket and the glycemic levels before, and after injection of local anesthesia with and without vasoconstrictor in diabetic patients
- Trial name
- NCT05875519
- Testing
- Local anaesthesia with vasocontrictor (Mepivacaine hydrochloride 20 mg (2%) + Levonordefrin hydrochloride 0.06 mg)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Obesity
Medium-term Effects of Molecular Hydrogen on Metabolic Fitness in Obesity
Molecular hydrogen (H2) effectively tackles obesity-related disorders in animal models yet no studies so far investigated the effectiveness of H2 for improving biomarkers of obesity in humans.
- Trial name
- NCT02832219
- Testing
- Molecular hydrogen
- Where
- Serbia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Hypertension, Diabetic Nephropathy
A Study in Patients With Diabetes Mellitus Type II of the Effect on Albuminuria of 24 Week Treatment With Valsartan, Benazepril, and Valsartan+Benazepril
The purpose of this study is to evaluate the efficacy of valsartan, benazepril or the combination of both in reduction of microalbuminuria in Type 2 diabetic patients.
- Trial name
- NCT00171119
- Testing
- valsartan
- Where
- Switzerland
- Volunteers
- 81 people
- Sponsor
- Novartis Pharmaceuticals
Gestational Diabetes
Postpartum Continuous Glucose Monitoring (CGM) Study
This research study is being done to assess if using a glucose sensor (also known as a continuous glucose monitor) after childbirth can help identify women who are at risk of developing diabetes after having diabetes during…
- Trial name
- NCT05714761
- Testing
- Dexcom glucose sensor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Psoriasis, Metabolic Syndrome
Response of Metabolic Syndrome and Sexual Dysfunction to Lifestyle Changes in Men With Psoriasis
complaint of sexual dysfunction and metabolic syndrome are highly reported in men with psoriasis
- Conditions
- Psoriasis, Metabolic Syndrome, Erectile Dysfunction
- Trial name
- NCT05632042
- Testing
- lifestyle modification (exercise and control of diet)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Healthy
Acute Intervention with Sulforaphane-Smart®
The Sulforaphane-Smartt® formula is a pill, patented by the company INGREDALIA, prepared with broccoli by-products which have been concentrated and enriched in glucosinolates/isothiocyanates (GLS/ITCs).
- Trial name
- SANO-Acute (NCT06856486)
- Testing
- Sulforaphan Smart®
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mª Jesús Periago
Diabetes
Surgical Treatment of Type 2 Diabetes in Non-Morbidly Obese Patients
The aim of this study is to assess the short term success and feasibility of ileal transposition with sleeve gastrectomy in non-morbidly obese patients with poorly controlled Type 2 Diabetes Mellitus
- Trial name
- NCT00596973
- Testing
- Surgical Treatment
- Where
- United States
- Sponsor
- Medtronic - MITG
Insulin Resistance
Prevalence of IR in Overweight and Obese Adolescents
The aim of this study is to determine the prevalence of Insulin Resistance (IR) among overweight and obese adolescents using HOMA-IR scores and identify lifestyle risk factors in the IR and Non-IR group.
- Trial name
- IR (NCT05810883)
- Testing
- Blood Tests; Serum Fasting Insulin and Glucose
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
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