Clinical trials: Glucose Metabolism
Type 2 Diabetes, Exercise
EXercise Capacity and TRAinability in Type 2 Diabetes (EXTRA-T2D)
Type 2 Diabetes (T2D) is a condition characterized by acelerated aging and is associated to multiple comorbidities, and physical fragility and disabilitiy, all of which reduce life expectancy and quality of life.
- Conditions
- Type 2 Diabetes, Exercise, Aging
- Trial name
- EXTRA-T2D (NCT05860842)
- Testing
- exercise
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Diabetes Mellitus
FreeStyle Libre Glucose Monitoring System Paediatric Study
The study is designed to determine glycaemic control achieved using the FreeStyle Libre Flash Glucose Monitoring System (FreeStyle Libre) versus Self-Monitoring Blood Glucose (SMBG) for the self-management of diabetes.
- Trial name
- SELFY (NCT02821117)
- Testing
- FreeStyle Libre Flash Glucose Monitoring System
- Where
- 10 sites in Germany, Ireland and 1 more
- Volunteers
- 76 people
- Sponsor
- Abbott Diabetes Care
Type 2 Diabetes Mellitus
Clinical Evaluation of Fenfuro (Fenugreek Seed Extract) in Type-2 Diabetic Subjects: an add-on Study
This study is an open label, two armed trial evaluating the safety and efficacy of Fenfuro capsule twice daily for 90 days in 100 patients with type 2 diabetes that will be conducted in single center in India.
- Trial name
- NCT03066089
- Testing
- Fenfuro
- Where
- India
- Volunteers
- 104 people
- Sponsor
- Chemical Resources
Multidisciplinary Approach, Clinical Pharmacists
Multidisciplinary Approach to Improve Diabetic Foot Care: an Investigation of Clinical and Economic Outcomes.
The study intervention was applying multidisciplinary approach consisting of an endocrinologist, a diabetes specialized nurse, and a clinical pharmacist to assess and improve diabetic foot care using a systematic screening…
- Conditions
- Multidisciplinary Approach, Clinical Pharmacists, Diabetic Foot Ulcer (DFU), Multidisciplinary Care Team
- Trial name
- NCT06658691
- Testing
- Multidisciplinary approach
- Where
- Jordan
- Volunteers
- 119 people
- Sponsor
- University of Jordan
Obesity, Insulin Resistance
Systemic Cross-talk Between Brain, Gut, and Peripheral Tissues in Glucose Homeostasis: Effects of Exercise Training
Obesity and insulin resistance are worldwide epidemic and taking a major public health toll. Obesity also increases the risk for cognitive impairment which is also an increasing medical, societal, and economic challenge.
- Conditions
- Obesity, Insulin Resistance, Type2 Diabetes, Exercise Training
- Trial name
- CROSSYS (NCT03730610)
- Testing
- Exercise training
- Where
- Finland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Turku
Diabetes Type 2
Connected Care for Type 2 Diabetes Self-Management
The primary objective of this Randomized Clinical Trial is to improve the self-management (SM) competencies of patients affected by Type 2 Diabetes Mellitus (T2DM) living in the Marche region (Italy) through the support of a…
- Trial name
- RCT_SM (NCT07149610)
- Testing
- M-health solution classified as Class I Medical Devices, equipped with a CE certificate. The m-health solution will be integrated with the EPR currently used by the CADs of the Marche region
- Where
- 11 sites in Italy
- Volunteers
- 388 people
- Sponsor
- Marche Region Regional Health Agency
Peripheral Arterial Disease
Multicentre Study to Investigate the Performance of the Padd Device in the Assessment of Peripheral Arterial Disease
The study will compare Padd, a non-invasive automated optical device which uses a functional test to assess peripheral arterial disease (PAD), and Ankle brachial pressure index (ABPI) in the detection of PAD using as a gold…
- Trial name
- NCT01633710
- Where
- 2 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- University Hospitals, Leicester
Hypertension, Diabete Mellitus
"Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Revascularization Patients
This study aims to evaluate the effect of an AI-assisted "Smart family doctor" digital health management tool on improving the control rates of hypertension, diabetes, and dyslipidemia in post-revascularization patients.
- Conditions
- Hypertension, Diabete Mellitus, Hyperlipidemia, Post PCI
- Trial name
- SMART II (NCT07273513)
- Testing
- Smart family doctor, Health manager, Usual Care
- Volunteers
- 951 people
- Sponsor
- China National Center for Cardiovascular Diseases
Type 2 Diabetes
THC Effects on Glucose in Type 2 Diabetes
This study will examine the effects THC has on Glucose Metabolism and Endothelial Functioning in participants with Type 2 Diabetes.
- Trial name
- NCT05322213
- Testing
- THC
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Type 2 Diabetes
Diet and Exercise Intervention in Type 2 Diabetes
The purpose of this study is to determine the effect of a worksite-based intensive lifestyle therapy intervention (weight loss with exercise training) on blood sugar control in people with obesity and type 2 diabetics.
- Trial name
- LID (NCT01977560)
- Testing
- Intensive Lifestyle Intervention, Standard Care
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Washington University School of Medicine
Type 1 Diabetes Mellitus (T1DM), Healthy Control
Environmental Determinants of Type 1 Diabetes Risk
To analyze the environmental risk factors for type 1 diabetes in China.
- Conditions
- Type 1 Diabetes Mellitus (T1DM), Healthy Control, Relatives to/Carers of Patients
- Trial name
- NCT07835724
- Where
- China
- Volunteers
- 11,240 people, healthy volunteers welcome
- Sponsor
- Second Xiangya Hospital of Central South University
Hypertriglyceridemia, Overweight , Obesity
Standardized Large Yellow Tea Extract for Glucose and Lipid Metabolism in Overweight Adults With Hypertriglyceridemia
This multicenter, prospective, randomized, blinded, parallel-group controlled trial will evaluate the effects of standardized large yellow tea extract on glucose and lipid metabolism in overweight adults with elevated…
- Trial name
- NCT07840846
- Testing
- Standardized Large Yellow Tea Extract
- Volunteers
- 138 people
- Sponsor
- The First Affiliated Hospital of China University of Science and Technology (Anhui Provincial)
Peripheral Vascular Diseases, Cardiovascular Disease
Vascular Regenerative Cell Exhaustion in Adults With Peripheral Artery Disease (PAD-VRCE)
PAD-VRCE is an observational, cross-sectional, two arm study aimed at determining if the presence of peripheral artery disease (PAD) can influence the number of circulating regenerative cells in blood.
- Conditions
- Peripheral Vascular Diseases, Cardiovascular Disease, Type 2 Diabetes, Peripheral Artery Disease
- Trial name
- PAD-VRCE (NCT06626646)
- Where
- 2 sites in Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Diabetes Mellitus
Sugarsquare. Focus on the Adolescent: Digital Treatment of Type 1 Diabetes Through the Internet
Background The treatment of diabetes is multidisciplinary. Alignment of care of the various professional disciplines is, however, not always optimal.
- Trial name
- NCT01249742
- Testing
- Internet intervention
- Where
- Netherlands
- Volunteers
- 65 people
- Sponsor
- Radboud University Medical Center
Type 1 Diabetes Mellitus
Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus
Phase 2 Trial of BMF-219 in Participants with Type 1 Diabetes Mellitus.
- Trial name
- NCT06152042
- Testing
- BMF-219
- Where
- 11 sites in United States, Canada
- Volunteers
- 37 people
- Sponsor
- Biomea Fusion Inc.
Type 2 Diabetes Mellitus (T2DM), Diabetic Foot Disease
NAFF Arabic Validation Study
This study aims to evaluate a new Arabic version of the NAFF questionnaire, which measures foot care behaviors in adults with type 2 diabetes.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Diabetic Foot Disease, Behavior, Self Care
- Trial name
- NCT07271550
- Where
- Tunisia
- Volunteers
- 255 people
- Sponsor
- Faculty of Medicine, Sousse
Diabetes Mellitus, Type 2
A Study to Determine the Safety and Efficacy of Albiglutide Administered in Combination With Insulin Glargine
This study will examine the safety and efficacy of albiglutide in combination with insulin glargine as compared with the combination of insulin glargine and preprandial lispro insulin in subjects with type 2 diabetes.
- Trial name
- NCT00976391
- Testing
- albiglutide + insulin glargine, insulin glargine + preprandial lispro insulin
- Where
- 209 sites in United States, Brazil and 12 more
- Volunteers
- 586 people
- Sponsor
- GlaxoSmithKline
Obesity, Insulin Resistance
Role of Adipose Tissue in Pathogenesis of Insulin Resistance
The aim of the study was to investigate the relationship between insulin resistance and body composition in relation to secterion and expression of adipocytokines.
- Trial name
- NCT00439491
- Testing
- Hypocaloric diet
- Where
- Czechia
- Volunteers
- 35 people
- Sponsor
- Charles University, Czech Republic
Type 1 Diabetes
A Trial Investigating the Accuracy of Continuous Glucose Monitor Systems ("Supersapiens" Abbott Libre Sense and Dexcom G6) During Exercise in People With Normal Glucose Tolerance
A two-phase, observational trial in an exercise laboratory and a prospective real-world setting to test the hypothesis that The Libre Sense Glucose Sport device has acceptable accuracy in people with normal glucose tolerance and…
- Trial name
- SuperComEx (NCT06034574)
- Testing
- Continuous glucose monitoring
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Diabetes
Therapeutic Effects and Effects on Body Fat of GLP-1 Receptor Agonists in Patients With Type 2 Diabetes for 1-4 Years
The efficacy of long-term treatment with different GLP-1RA (Duragtide, Semaglutide, losenatide, tirzepatide, ebenatide, etc.) was evaluated through 1-4 years of follow-up, and the effects of long-term treatment on blood glucose…
- Trial name
- NCT05990374
- Testing
- Duragtide, Semaglutide, losenatide, tirzepatide, ebenatide, etc
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
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