Clinical trials: Glucose Metabolism
Type1diabetes, Hypoglycemia
Prediction and Prevention of Nocturnal Hypoglycemia in Persons With Type 1 Diabetes Using Machine Learning Techniques
The objective is to develop a novel system to predict and prevent nocturnal hypoglycemia in type 1 diabetic (T1D) patients, focused in patients with multiple daily injections (MDI) therapy.
- Trial name
- NCT03711656
- Testing
- isCGM (intermittently scanned Continuous Glucose Monitoring), Physical exercise tracker
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Hospital Clinic of Barcelona
Asthma, Diabete Type 2
Bronchial Asthma and Diabetes: Impact on Bronchial Inflammation and Exercise Capacity
Type 2 diabetes is the most common form of diabetes and according to several studies, even lung can represent another target of the diabetic disease.
- Trial name
- NCT04448262
- Testing
- data collection
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Type 2 Diabetes Mellitus (T2DM)
Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) Assessment of LIK066 in Healthy Subjects and in Patients With Type 2 Diabetes Mellitus (T2DM)
This study will assess safety, tolerability, and effect of LIK066 on blood glucose in healthy subjects and in patients with T2DM.
- Trial name
- NCT01407003
- Testing
- LIK066
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Coronary Disease
Comprehensive Analyses of Multidetector-row Cardiac Computed Tomography Data in Koreans
64 channel multidetector-row Computed Tomography (CT) has been introduced for use in the diagnosis of coronary heart disease. The investigators aimed to characterize coronary artery disease in type 2 diabetes mellitus and…
- Trial name
- NCT01170403
- Where
- South Korea
- Volunteers
- 15,000 people
- Sponsor
- Seoul National University Bundang Hospital
Obesity, Type 2 Diabetes
Lifestyle Management of CKD in Obese Diabetic Patients
The purpose of this randomized clinical trial is to evaluate the efficacy of 3 different technology-supported approaches to engaging 300 individuals with diabetes and concurrent chronic kidney disease in weight loss, dietary…
- Conditions
- Obesity, Type 2 Diabetes, Chronic Kidney Disease (CKD)
- Trial name
- NCT02276742
- Testing
- Social Cognitive Theory, Monitoring
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- NYU Langone Health
Diabetes Mellitus, Type 2
A Clinical Study to Evaluate the Use of Episodic, Intensive Blood Glucose Monitoring in Persons With Non-insulin Treated Type 2 Diabetes
This randomized, parallel group study will determine whether the use of episodic, intensive glucose monitoring via the Accu-Chek 360 view blood glucose analysis system has a positive effect on overall glycemic control.
- Trial name
- NCT00674986
- Testing
- Accu-Chek 360° View Blood Glucose Analysis Tool, Accu-Chek Aviva Glucose Meter
- Where
- 29 sites in United States
- Volunteers
- 522 people
- Sponsor
- Hoffmann-La Roche
Type 2 Diabetes
Delapril and Manidipine for Nephroprotection in Diabetes (DEMAND)
Diabetes mellitus is one of the most common diseases globally, and is considered epidemic in many developed and newly industrialized nations.
- Trial name
- NCT00157586
- Testing
- Delapril, Delapril-Manidipine Fixed combination
- Where
- 8 sites in Italy, Slovenia
- Volunteers
- 342 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Diabetes Mellitus, Hypoglycemia Unawareness
Prevention Through Intervention: Telehealth Solution to Deter 911 Calls Due to Hypoglycemia
This study aims to standardize and evaluate the benefits of the Prevention to Intervention program offered by the Birmingham Fire and Rescue Service.
- Conditions
- Diabetes Mellitus, Hypoglycemia Unawareness, Hypoglycemia, Hypoglycemia Acute
- Trial name
- NCT03665870
- Testing
- Hypoglycemia Education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham
Psoriatic Arthritis
Metformin in Psoriatic Arthritis
Psoriatic arthritis (PsA) is a systemic, inflammatory disease. The chronic inflammation in PsA predisposes patients to the metabolic syndrome (MetS). MetS is associated with systemic inflammation and proinflammatory cytokines.
- Trial name
- NCT02188654
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- University of Alexandria
Type 1 Diabetes
Cohort Study of Patients With Type 1 Diabetes Registered With Mobile Application in China
For last decade, the innovation of mobile health platform has brought new opportunities for disease management. Previous studies have shown that health management programs based on mobile platforms for patients with diabetes can…
- Trial name
- COOPERATIONS (NCT05163054)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking University Third Hospital
Type 2 Diabetes Mellitus
Effects of Triacylglycerol Structure on Gut Hormones and Haemostatic Markers
Type 2 diabetes mellitus (T2DM) is a chronic disorder determined by lifestyle and genes. It is associated with chronic hyperglycaemia along with other metabolic abnormalities.
- Trial name
- NCT01906359
- Testing
- Native palm olein (IV56), Chemically interesterified palm olein (IV56), High oleic sunflower oil
- Where
- 5 sites in Malaysia
- Volunteers
- 23 people
- Sponsor
- Malaysia Palm Oil Board
Diabetes Mellitus, Type 1
Trial Comparing Metabolic Efficiency of Islet Graft to Intensive Insulin Therapy for Type 1 Diabetes's Treatment
Efficacy of pancreatic islet transplantation at 6 months compared to an intensive insulin therapy for 2 categories of patients: patients with unstable diabetes and patients who underwent kidney transplantation.
- Trial name
- TRIMECO (NCT01148680)
- Testing
- Islet Graft
- Where
- 9 sites in France, Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Grenoble
Type 2 Diabetes
Real-world Effects of Using Intermittently Scanned Continuous Glucose Monitoring and Pharmacist-led Coaching on the Management of Type 2 Diabetes Among Adults Not Using Insulin (REAL isCGM T2D)
The goal of this prospective study is to evaluate diabetes outcomes after initiating second generation intermittently scanned continuous glucose monitoring (isCGM) plus one pharmacist consultation session compared with capillary…
- Trial name
- REAL isCGM T2D (NCT06837103)
- Testing
- Intermittently Scanned Continuous Glucose Monitor
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Infections, Heart Failure
Rural Hospital-Level Care at Home for Acutely Ill Adults
This study examines the implications of providing hospital-level care in rural homes.
- Conditions
- Infections, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT05256303
- Testing
- Home Hospital care, Traditional Hospital care
- Where
- 3 sites in United States, Canada
- Volunteers
- 160 people
- Sponsor
- Brigham and Women's Hospital
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Obesity
Optimized Cardioprotection Therapy in Obese Subjects With CAD
The purpose of this study is to investigate the efficacy and mechanism of Adipokines Cardiac Protection in Obese Patients With coronary artery disease (CAD).
- Conditions
- Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Obesity, Adiposis; Heart
- Trial name
- NCT04570527
- Testing
- PCI
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital
Sedentary Behavior, Metabolic Syndrome
Multi-organ Responses to CHronic Physical Activity and INactivity
Life expectancy has been increasing for the last 150 years, but the maintenance of health has not kept pace with increased lifespan, and on average, UK adults spend the last decade of life in poor-health, with major consequences…
- Conditions
- Sedentary Behavior, Metabolic Syndrome, Age-related Cognitive Decline, Age-Related Sarcopenia
- Trial name
- CHAIN (NCT06377254)
- Testing
- Decreased Physical Activity, Increased Physical activity
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Diabetic Peripheral Neuropathy
Effect of Pulsing Electrical Fields on Lower Extremity Diabetic Neuropathy: A Pilot, Open-Label Study
To determine if pulsed electric field therapy reduces lower leg and foot pain associated with diabetic neuropathy and lessens the need for medication.
- Trial name
- DPN (NCT00614341)
- Testing
- MedRelief SE 55
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- MedRelief
Obesity, Type II Diabetes
Using EEG Operant Conditioning to Improve Trait Self-Control and Promote Healthy Behavior
The field of neuroeconomics has begun to elucidate neural mechanisms underlying self-control; however, researchers have not yet harnessed neuroeconomics findings to develop interventions for improving self-control ability.
- Conditions
- Obesity, Type II Diabetes, Cardiovascular Disease, Health Behavior
- Trial name
- NCT01801254
- Testing
- STRIDES
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Diabetes Mellitus, Type 2, Obesity
Type 2 Diabetes, Obesity and Cortisol Excess
The present observational cross-sectional study is aimed to assess: the hidden hypercortisolism (HidHyCo) prevalence in a sample of Type 2 diabetes (T2D) patients and the clinical characteristics more frequently associated with…
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Cortisol; Hypersecretion
- Trial name
- DOCOR (NCT05759637)
- Testing
- 1mg DST
- Where
- 5 sites in Italy
- Volunteers
- 3,200 people
- Sponsor
- Istituto Auxologico Italiano
Hyperlactatemia, Metabolic Syndrome (MetS)
Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism.
The purpose of this study is to investigate whether the elevated circulating lactate levels of individuals with metabolic syndrome are responsible for their reduced lipolysis and glucose tolerance.
- Conditions
- Hyperlactatemia, Metabolic Syndrome (MetS), Lipolysis, Exercise
- Trial name
- LACTMET (NCT07426172)
- Testing
- hyperlactacidemia, Saline (0.9%, sterile, for infusion)
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ricardo Mora
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.