Clinical trials: Glucose Metabolism
Insulin Resistance
Substudy of Change in Cardiometabolic Disease (CMD) Risk Factors During an Interactive Fitness Program
Substudy examining cardiovascular and metabolic risk factor change in children at high risk for future atherosclerosis who are enrolled in a pilot intervention using novel gaming and exercise activities to increase physical…
- Trial name
- EXCEL (NCT01080339)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pregnancy, Gestational Diabetes
A Feasibility Study Looking at the Use of Glibenclamide and metfoRmin Versus stAndard Care in gEstational diabeteS
The aim of this open label feasibility study is to determine recruitment rates to a randomised trial of glibenclamide compared with insulin (both in addition to maximum tolerated metformin) for the treatment of Gestational…
- Trial name
- GRACES (NCT02080377)
- Testing
- Glibenclamide, Insulin
- Where
- 5 sites in United Kingdom
- Volunteers
- 23 people
- Sponsor
- University of Edinburgh
Metabolic Syndrome
Effect of Arabinoxylan Oligosaccharides Consumption on Insulin Resistance in Patients With Metabolic Syndrome
During this project the investigators will evaluate whether the effects of arabinoxylan oligosaccharides (AXOS) consumption on insulin resistance in participants with metabolic syndrome can be explained by the production of…
- Trial name
- NCT02623777
- Testing
- Arabinoxylan oligosaccharides, Short chain fatty acids
- Volunteers
- 9 people
- Sponsor
- KU Leuven
Gestational Age, Birth Weight
Resistance Exercise Training During Pregnancy: a Randomized Controlled Trial
The investigators investigated the effects of a supervised maternal exercise training program (performed during the 2nd and 3rd trimesters of pregnancy) on maternal-newborn unit health outcomes in a group of previously sedentary…
- Conditions
- Gestational Age, Birth Weight, Anaemia, Gestational Diabetes Mellitus
- Trial name
- NCT00813657
- Testing
- Exercise
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Diabetes Mellitus, Type 2
Chronic Effects of Two Aerobic-training Models Performed in Water and on Dry Land in Patients With Type 2 Diabetes Mellitus (T2DM).
The aim of this study was to analyse the acute and chronic effects of two aerobic-training models performed in water and on dry land on cardiorespiratory, functional, metabolic, hormonal and quality-of-life parameters in patients…
- Trial name
- NCT01956357
- Testing
- Aquatic exercise, Land Exercise
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Dehydration
Effects of Amino Acid/Electrolyte-based Beverages on Hydration Status
Older adults typically do not drink later in the day to avoid the necessity of interrupting sleep to urinate. Sometimes they also limit ingestion of fluids to avoid the need to urinate when engaged in certain activities such as…
- Trial name
- NCT03559101
- Testing
- Distilled water, Medical Food 1, Medical Food 2
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- W. Larry Kenney
Diabetes Mellitus, Type 2
Pharmaceutical Care Service in Diabetes
The purpose of this study is to examine the effectiveness of pharmaceutical care service in the management of poorly controlled type 2 diabetes mellitus.
- Trial name
- IMPACT4-DM (NCT02955875)
- Testing
- Pharmaceutical care
- Volunteers
- 257 people
- Sponsor
- Pusan National University
Diabetes Mellitus
Effect of Insulin Therapy by Ultrasonography in Wound Healing of Chronic Diabetic Patients
The main aim of the study is to determine the effect of transdermal application of insulin therapy by phonophoresis in wound healing in diabetic patients the main question of the study: is insulin phonophoresis is effective in…
- Trial name
- NCT06708975
- Testing
- Insulin therapy phonophoresis, Hyperpolarized light therapy and Standard wound cleaning and dressing.
- Volunteers
- 40 people
- Sponsor
- MTI University
Obesity
Medium-term Effects of Molecular Hydrogen on Metabolic Fitness in Obesity
Molecular hydrogen (H2) effectively tackles obesity-related disorders in animal models yet no studies so far investigated the effectiveness of H2 for improving biomarkers of obesity in humans.
- Trial name
- NCT02832219
- Testing
- Molecular hydrogen
- Where
- Serbia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Type2 Diabetes Mellitus
Diabetes Nutrition Education With Glycemic Control
T2DM in Indonesia has increased dramatically from 7.0% in 2017 to 10.9% in 2018. In Padang, West Sumatra, diabetes prevalence was 1.3% in 2013 and increased slowly in 2018.
- Trial name
- NCT04440319
- Testing
- Intervention group
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Andalas University
Type 2 Diabetes
The Effect of the Interdisciplinary Care Approach on General Health Parameters in Older Adults With Type 2 Diabetes
The aim of the study was evaluation of the effect of the clinical Pilates, nurse coaching and Peer group work Approach on General Health Parameters in older adults with Diabetes.
- Trial name
- NCT07165119
- Testing
- Interdisciplinary group, Clinical Pilates Group, Nurse Coaching group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Type 2 Diabetes Mellitus
The Efficacy and Treatment Adherence With an Integrated Program on HbA1c Scores in Patients With Type 2 Diabetes
It is hypothesized for this study that the coupling of the Millon Behavioral Medicine Diagnostic, biopsychosocial evaluation, motivational interviewing, relapse prevention, and ongoing support can produce improved outcomes with…
- Trial name
- ASMART (NCT01626053)
- Testing
- ASMART, Control Group
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- KRJG Services Inc.
Diabetes
Nutritional Regulation of Wound Inflammation: Part II
Fermented Papaya Preparation (FPP) is a sweet and granular substance available over the counter. FPP possesses antioxidant properties, which provide benefit against age-related complications, and is also known to protect red…
- Trial name
- FPPT2DM-II (NCT01618045)
- Testing
- Fermented Papaya Preparation (FPP)
- Where
- 5 sites in United States
- Volunteers
- 24 people
- Sponsor
- Ohio State University
Intervention Study
Intervention Study on Medication Reconciliation Among Pharmacists in Two Tertiary Hospitals in Nigeria
This study will assess the current practice of medication reconciliation among pharmacists in the selected institutions with a view to making an intervention to address gaps discovered
- Trial name
- NCT03182972
- Testing
- Medication reconciliation
- Where
- 2 sites in Nigeria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
Diabetes, Anesthesia, Local
Healing Process and Blood Sugar Level Following Local Anesthetic Infiltration With and Without Vasoconstrictor
Evaluating the healing of the extraction socket and the glycemic levels before, and after injection of local anesthesia with and without vasoconstrictor in diabetic patients
- Trial name
- NCT05875519
- Testing
- Local anaesthesia with vasocontrictor (Mepivacaine hydrochloride 20 mg (2%) + Levonordefrin hydrochloride 0.06 mg)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Type 1 Diabetes Mellitus
T Cell Validation Study Using Blood Samples From Subjects With Recent Onset Type 1 Diabetes Mellitus
Type 1 diabetes is a condition that is caused in part by an abnormality of the immune system which occurs when T cells, which are part of the immune system, damage the insulin secreting cells (islet cells) in the pancreas.
- Trial name
- NCT00212329
- Testing
- T Cell Proliferation and Autoreactivity Assays, Cellular Immunoblot Assays, Tetramer Studies
- Where
- 14 sites in United States, United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes, Neuropathy, Painful
Methylglyoxal Evaluation in Humans
The investigators will test the hypothesis that patients with low back pain associated with lumbar disc aberrancy will have elevated MGO-protein levels circulating in the blood that are comparable to patients with painful…
- Conditions
- Type 2 Diabetes, Neuropathy, Painful, Chronic Low-back Pain, Lumbar Disc Herniation
- Trial name
- MEH (NCT05350553)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Diabetes Mellitus
Evaluation of Diabetic Foot Wound Healing Using Hydrogel/Nano Silver-based Dressing vs. Traditional Dressing
Background: The wound dressings perform a crucial role in the cutaneous wounds' management due to their ability to protect wounds and promote dermal and epidermal tissue regeneration.
- Trial name
- NCT04834245
- Testing
- Hydrogel/nano silver-based dressing
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Magda Bayoumi
Diabetes Mellitus, Type 2
Efficacy and Safety of Insulin Rinsulin® NPH Compared to Humulin® NPH in Type 2 Diabetes Mellitus Patients
The study is designed to approve non-inferior efficacy and safety of Rinsulin® NPH compared to Humulin® NPH.
- Trial name
- NCT04012775
- Testing
- Insulin Humulin® NPH, Insulin Rinsulin® NPH
- Where
- 14 sites in Russia
- Volunteers
- 201 people
- Sponsor
- Geropharm
Insulin Resistance, Metabolic Syndrome x
Insulin Resistance Study
The purpose of this study is to evaluate how often patients with hepatitis C infection have abnormalities of sugar and fat utilization.
- Trial name
- IR (NCT00614757)
- Testing
- N-acetylcysteine 20% 4ml, N-acetylcysteine 20% in 4 ml
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Midwest Biomedical Research
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