Clinical trials: Glucose Regulation
Overweight, Obesity
Mono Unsaturated Fatty Acids in Obesity - Weight Maintenance and Prevention of Lifestyle Diseases in Obese Subjects.
The purpose of this study is to investigate the effect of three diets different in type and amount of fat in weight maintenance and prevention of life-style diseases in obese subjects.
- Trial name
- NCT00274729
- Testing
- Mono Unsaturated Fatty Acids in Obesity
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy, Diabetes Mellitus Type 1
The Effect of Light Therapy on Cellular Energy and Oxidative Stress in Healthy Adults and Type 1 Diabetic Patients
The goal of this clinical trial is to evaluate the effects of low-level light therapy on cellular energy and oxidative stress in healthy adults and patients with Type 1 diabetes.
- Trial name
- PBM-T1D (NCT07833865)
- Testing
- Red and Near-Infrared Light Therapy Pad
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thi-Qar
Obesity, Weight Loss
Hormonal Regulation of Body Weight Maintenance
The investigators here propose to perform a collaborative clinical research effort including a randomized controlled trial investigating the mechanisms of weight maintenance and their relation to a lifestyle intervention in…
- Conditions
- Obesity, Weight Loss, Weight Gain, Hormone Disturbance
- Trial name
- NCT00850629
- Testing
- multimodal lifestyle intervention
- Where
- Germany
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Obesity and Type 2 Diabetes, Diet Modification
Mobile Regulation of Craving Training (mROC-T) to Improve Dietary Intake in Rural Adolescent Girls
The goal of this clinical trial is to test if a regulation of craving training intervention in the form of a mobile phone app can increase fruit and vegetable intake in adolescent girls ages 14-18 years of age.
- Trial name
- ROC Teens! (NCT06723028)
- Testing
- Regulation of craving training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Oxidative Stress
The Acute Effect of Spices on Vascular Health
The investigators aim to conduct a 3-period randomized controlled crossover study to investigate the postprandial effects of a high fat meal with spice on endothelial function, lipids/lipoproteins, immune function and plasma…
- Trial name
- NCT03064958
- Testing
- Herbs and spices, High fat meal
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Penn State University
Roux-en-y Gastric Bypass, Post Prandial Hypoglycemia
Evaluation of the Neuro-endocrine Response to Post-prandial Hyperinsulinaemic Hypoglycaemia.
The primary objective of this study is to assess the neuro-endocrine response to hypoglycaemia in PHH vs. non-PHH post-gastric bypass individuals.
- Trial name
- DEEP1B (NCT04334161)
- Testing
- Administration of glucose and controlled induction of hypoglycaemia.
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Lia Bally
Healthy
Effect of Herbs and Spices on Metabolic Regulation and Appetite in Healthy Subjects
The purpose of the study is to investigate how herbs and spices affect acute/postprandial glucose and insulin responses, inflammatory markers, appetite control peptides, antioxidative capacity, as well as subjective appetite…
- Trial name
- AFC-SPICES (NCT02035241)
- Testing
- Spices 1, Spices 2, Spices 3
- Where
- Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Lund University
Healthy Diet
Effect of Ultra Processed Versus Unprocessed Diets on Energy Intake
Background: Eating too much processed food is believed to lead to obesity. But the effect of processed food on energy intake has not been carefully studied.
- Trial name
- NCT03407053
- Testing
- Ultra-processed diet, Unprocessed diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy Aging, Inflammaging
The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health
The goal of this clinical trial is to learn if Quercefit® or Ubiqsome™ can improve markers of healthy aging, blood sugar control, and heart health in older adults. It will also learn about the safety of these supplements.
- Conditions
- Healthy Aging, Inflammaging, Metabolic Health, Quercetin
- Trial name
- NCT07760506
- Testing
- Quercetin (dietary supplement), Coenzyme Q10, Rice Flour
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Insulin Secretion
Glucagon Regulation of Glucose Metabolism
Glucagon is a 30 amino acid peptide hormone that is produced exclusively in alpha-cells of the pancreatic islets. Glucagon binds to a G-protein coupled receptor and activates intracellular signaling by increasing the synthesis of…
- Trial name
- NCT04347252
- Testing
- Glucagon
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- David D'Alessio, M.D.
Obesity, Overweight
A Study of the Effects of Fish Protein Intake on Glucose Regulation in Overweight and Obese Adults.
The purpose of this study is to compare the possible health benefits of intake of proteins from salmon, herring, cod and milk on glucose tolerance in overweight and obese adults.
- Trial name
- FISK3 (NCT01641055)
- Testing
- Salmon protein hydrolysate, Herring protein hydrolysate, Cod protein
- Where
- Norway
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Obesity, Prediabetes
Effects of a GLP-1 Formula Drink on Gut Microbiota and Glycemic Control in Prediabetic Individuals
A clinical human dietary intervention trial was conducted to investigate the effects of GLP-1 FORMUL liquid supplementation in individuals with prediabetes or obesity, with a focus on improvements in glycemic and lipid…
- Trial name
- NCT07089732
- Testing
- GLP-1 formula liquid drink
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Type 2 Diabetes Mellitus
Insulin Receptor Substrate 1 (IRS-1) Regulation in Insulin Resistance
The study is being conducted to find out why too much fat in your blood stream may cause insulin resistance in your muscles. Insulin is the hormone, produced normally by your body, which causes your blood sugar to return to…
- Trial name
- NCT01240252
- Testing
- Human insulin
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Food Intake Regulation, Substrate Oxidation
Substrate Oxidation Does Not Affect Short Term Food Intake in Healthy Boys and Men
The purpose of this study is to investigate the effect of substrate oxidation, expressed by RER, on food intake regulation and net energy balance.
- Trial name
- NCT01888991
- Testing
- Glucose Preload and Exercise Intervention
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Myocardial Ischemia, Autonomic Neuropathy
Coronary Blood Flow Regulation During General Anesthesia
The central hypothesis in the present project is that general anesthesia may alter autonomic control such that perioperative coronary blood flow (CBF) is significantly disturbed.
- Conditions
- Myocardial Ischemia, Autonomic Neuropathy, Healthy, Diabetes
- Trial name
- NCT00866801
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Appetite
Cereal-based Products Fortified With Legumes and Effects on Glycemic Control and Appetite Regulation
Legumes are rich source of proteins and dietary fibers which are associated with satiety and amelioration of postprandial glycemic response.
- Trial name
- NCT03974165
- Testing
- Cereal-legume product 1, Cereal-legume product 2, Cereal product
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Prediabetes
Regulation of Postprandial Nitric Oxide Bioavailability and Vascular Function By Dairy Milk
Cardiovascular disease (CVD) is the leading cause of death in the United States. Short-term increases in blood sugar, or postprandial hyperglycemia (PPH), affect blood vessel function and increase the risk of CVD.
- Trial name
- NCT02482675
- Testing
- Glucose, Glucose with Non-fat Milk, Glucose with Whey Protein Isolate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Inflammation, Glucose Regulation
Tart Cherry Supplementation & Gut Microbiome and Inflammation
There has been a rapid increase in researching the use of tart cherry supplements in the past 5 years, particularly for inflammatory conditions.
- Conditions
- Inflammation, Glucose Regulation, Sleep
- Trial name
- NCT04467372
- Testing
- Tart cherry juice concentrate, Freeze dried tart cherry powder
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio University
Glucose Regulation, Low-grade Inflammation
Effect of Milk Ingredients on Glucose Regulation and Inflammation
Background: Recent advances in science have established a fundamental role for low grade chronic inflammation in mediating all stages of most of the non-communicable diseases associated with ageing.
- Trial name
- NCT02011672
- Testing
- nutrient-enriched milk, regular milk
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NIZO Food Research
NAFLD, Overweight and Obesity
The Role of Dietary Carbohydrate and Fat Availability in the Regulation of Hepatic Lipid Content
The purpose of this study is to investigate dietary compositions effect on liverfat measured by magnetic resonance imaging.
- Conditions
- NAFLD, Overweight and Obesity, Metabolic Syndrome, Diabetes
- Trial name
- LICARB (NCT04581421)
- Testing
- High Carb Low Fat Diet, Low Carb High Fat Diet
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital