Clinical trials: Glucose Regulation
Diabetes Mellitus, Type 1
Glutathione Metabolism in Adolescents With Type 1 Diabetes - Study A
Glutathione is normally present at high (millimolar) levels in blood and plays an important role in the body's defense against oxidative stress, that is, against the damage caused to the body by reactive oxygen species produced…
- Trial name
- NCT00858897
- Testing
- Cysteine isotope infusion at normoglycemia vs hyperglycemia, Regular Insulin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nemours Children's Clinic
Type 1 Diabetes Mellitus
Efficacy of the "Living With Type 1 Diabetes to Grown-Up" Interactive Podcast Program
The present study aims to evaluate the intervention effectiveness of the Online Interactive Podcast Program"Living with Type 1 Diabetes to Grown-Up"in patients with type 1 diabetes transitioning from adolescence to early…
- Trial name
- NCT06464640
- Testing
- Online Interactive Podcast Program "Living with Type 1 Diabetes to Grown-Up", E-book
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- Chang Gung University
Schizophrenia, Type 2 Diabetes Mellitus
Janssen - Glucose Regulation/Risp/Olanz
Abnormalities in peripheral glucose regulation and type 2 diabetes can occur more commonly in individuals with schizophrenia than in healthy subjects or in other psychiatric conditions.
- Trial name
- NCT00205738
- Testing
- Risperidone, Olanzapine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus
A Study to Evaluate the Blood Glucose Regulation and Safety of PPB-R-203-02 Based Noodle Versus Commercially Available Wet Noodle in Patients With Diabetes
To evaluate the result of PPB-R-203-02 based noodle and commercially available wet noodle on blood glucose control in 24 patients with diabetes for 2 days.
- Trial name
- NCT01102452
- Testing
- Commercially Available Wet Noodle, PPB-R-203-02 Noodle
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Pharma Power Biotec Co., Ltd.
Diabetes Mellitus, Type 2
Pharmacist Assisted Medication Program Enhancing the Regulation of Diabetes
The purpose of this study is to demonstrate that pharmacists working collaboratively with physicians and other providers in an ambulatory care setting can improve glucose, blood pressure, and lipid control, as well as improve…
- Trial name
- PAMPERED (NCT00541606)
- Testing
- Pharmacist collaboration in diabetes care, Usual care
- Where
- United States
- Volunteers
- 285 people
- Sponsor
- Lahey Clinic
Obesity
Evaluation of Pulse Fibre Supplementation on Obesity and the Metabolic Syndrome
The recent dramatic increase in obesity has been linked to a reduction of dietary fibre intake. We hypothesized that supplementing the diet of overweight and obesity adults with pulse fibre will improve their metabolic status…
- Trial name
- NCT01719900
- Testing
- Pulse fibre, Control
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Calgary
PreDiabetes
Weight Loss for Prediabetes Using Episodic Future Thinking
The goals of the UH3 are to assess the effectiveness of adding Episodic Future Thinking (EFT) to the investigators standard behavioral weight control program to improve weight loss, delay discounting (DD), working memory…
- Trial name
- MINDD4 (NCT03670602)
- Testing
- Episodic Future Thinking, Daily Check in
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- State University of New York at Buffalo
Obesity
Impact of High Fiber Snacks on Adiposity, Glucose Regulation and Appetite
The primary objective of the proposed research is to determine the influence of 8 weeks of twice daily consumption of 120 kcal servings of dried apples or a commonly consumed low fat 120kcal muffin on components of obesity (waist…
- Trial name
- NCT02217124
- Testing
- dried apples, muffin
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Metabolic Disorders, Abdominal Obesity
Exploring Physical Exercise for the Regulation and Control of Metabolic Disorders in College Students.
This clinical trial objective is to evaluate the effect of an aerobic physical exercise program on reducing triglycerides, blood pressure, abdominal obesity, altered glucose levels, and the increase in HDL in college-level…
- Conditions
- Metabolic Disorders, Abdominal Obesity, Blood Pressure Disorders, Hypertriglyceridemia
- Trial name
- (EPE_RCTMCS) (NCT06555159)
- Testing
- Physical exercise prescription: Continuous aerobic training (jogging, swimming, static cycling), Control group: Continuous aerobic physical exercise
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad de Colima
Postural Orthostatic Tachycardia Syndrome (POTS), Healthy
POTS-FLOW: Interplay Between Gut Hormones and Autonomic Postprandial Blood Flow Regulation in Patients With POTS
This study will describe the interplay between the gut hormones GIP and CCK and their regulation of blood flow to the large vessels in patients with Postural Orthostatic Tachycardia Syndrome (POTS) and GIP, CCK and GLP-1 in…
- Trial name
- GA22 (NCT07019519)
- Testing
- GIPR antagonist, GLP-1R antagonist, CCK agonist
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity
Effect of Flaxseed on Lipid Uptake and Appetite
Randomized trial to test the effect of flaxseed fractions on appetite regulation and intestinal lipid absorption.
- Trial name
- NCT00465036
- Testing
- Whole flaxseeds, flaxseed mucilage, glucomannan
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Prediabetes, Autonomic Nervous System Imbalance
Enhancing the Vagal Tone in Prediabetes Individuals
This is a 2-year course of study. A randomized control trial will be conducted, in which 90 prediabetes individuals will be recruited and randomly assigned them into the wait-list control group or experimental group to test the…
- Conditions
- Prediabetes, Autonomic Nervous System Imbalance, Poor Glycemic Control, Psychological Distress
- Trial name
- NCT03616275
- Testing
- HRV biofeedback
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Defense Medical Center, Taiwan
Impaired Glucose Regulation, Impaired Glucose Tolerance (Prediabetes)
Probiotic Impact on Cognitive Performance, and Metabolic Outcomes in Overweight Young Adults With Impaired Glucose Regulation
This 12-week, double-blind, placebo-controlled trial will examine whether daily supplementation with the Lab4P probiotic can improve cognitive performance and metabolic health in overweight adults aged 18 to 40 with impaired…
- Conditions
- Impaired Glucose Regulation, Impaired Glucose Tolerance (Prediabetes), Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Overweight (BMI > 25)
- Trial name
- ProCog (NCT07073781)
- Testing
- Lab4p Probiotic Consortium
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Leeds Beckett University
Postprandial Blood Glucose Regulation
Effects on Metabolism and Cognitive Functions of a Commonly Used Commercial Food Supplement
This project evaluate effects of a commonly used food supplement on glucose metabolism and cognitive function.
- Trial name
- NCT02392819
- Testing
- Panax ginseng
- Where
- Sweden
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Lund University
Type 1 Diabetes
Comparison of the Use of Energy Substrates and Hormonal Regulation of Blood Sugar During Exercise of Increasing Intensity Between Children With Type 1 Diabetes and Non-diabetic Control Children.
The type 1 diabetes is a common chronic disease characterised by the stop of production of insulin by the pancreas. A lot of factors modify blood glucose.
- Trial name
- DIABSPORT (NCT03139864)
- Testing
- controlled physical activity
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Diabetes Mellitus, Type 2
RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes
This study is a phase 3b, multicentre, randomised, open label, parallel group study. A 4-week run-in period will be followed by a median of 6 years of treatment with study medication in addition to continuation of background…
- Trial name
- RECORD (NCT00379769)
- Testing
- Rosiglitazone, Sulfonylurea, Metformin
- Where
- 446 sites in Australia, Belgium and 23 more
- Volunteers
- 4,447 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 1
GPR119 Agonist for Hypoglycemia in Type 1 Diabetes
The purpose of this study is to test if a specific research medication could increase the response to low blood glucose in people with type 1 diabetes.
- Trial name
- PHROG (NCT04432090)
- Testing
- Study Medication (MBX-2982), No medication for this group
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Type 2 Diabetes, Self-regulation
Building Self-regulation Capacity in AA T2DM Women: Feasibility of EMI
In African-Americans, the incidence of type 2 diabetes (T2DM) is ~14%. Adherence to crucial diabetes self-management (DSM) behaviors, such as engaging in physical activity (PA) is dangerously low among AA women living in…
- Trial name
- NCT04083248
- Testing
- Feasibility group
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Illinois Chicago
Asthma
Effect of Inhaled Steroids on Glucose Regulation in Asthma Patients
Inhaled steroid has been the cornerstone in the treatment of asthma, which carries a huge patient population worldwide including Hong Kong. In general, the safety of long-term use of inhaled steroid has been well documented.
- Trial name
- NCT00959348
- Where
- 4 sites in Hong Kong
- Volunteers
- 1,394 people
- Sponsor
- The University of Hong Kong
Post Prandial Blood Glucose, Gut Microbiota
Intake of Beta-glucan and Postprandial Regulation of Blood Glucose Metabolism in Healthy Subjects
The overall aim is to investigate the intake of beta-glucan in relation to glucose metabolism and satiety in a postprandial study with healthy subjects.
- Conditions
- Post Prandial Blood Glucose, Gut Microbiota, Satiety
- Trial name
- NCT03293693
- Testing
- 0.5 g beta-glucan, 3.5 g beta-glucan, 8 g beta-glucan
- Where
- Norway
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University