Clinical trials: Glucose Response
Obesity, Overweight
The Effect of Eating Pulses for 8 Weeks on Satiety and Metabolic Syndrome Risk Factors in Overweight Individuals
In 2004, almost 60% of adult Canadians were overweight or obese. This is a serious health concern due to the burden of common health risks associated with being overweight and obese, including increased blood sugar, blood lipids…
- Trial name
- NCT00604448
- Testing
- Dietary advise, Diet enriched with a meal containing pulses
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Normal Weight, Overweight and Obesity
Effect Cinnamon Spice on Postprandial Glucose and Insulin Responses
The objective of the proposed study is to investigate the effect of cinnamon on the postprandial glycemic response to a high glycemic index meal in normal and overweight/obese prediabetic subjects
- Trial name
- CINNI (NCT04686552)
- Testing
- cinnamon
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Human Memory, Intranasal Insulin
fMRI Study of Effects of Nasal Insulin on Memory
Recent research has suggested insulin may be involved in how human's form and recall memories. This study is designed to look at how nasal insulin is used in the brain.
- Trial name
- NCT02758691
- Testing
- Intranasal Insulin, Intranasal Saline
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Insulin Resistance, Obesity
The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity, Preference and Brain Response in Adolescents
The purpose of this study is to investigate the effects of dietary exposure to artificial sweeteners on taste sensitivity, preference and brain response in adolescents using fMRI, psychophysical measures, and questionnaires.
- Trial name
- NCT02499705
- Testing
- Sucralose, Sucrose, Sucralose + maltodextrin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy
The Effect of a Natural Extract on the Post-prandial Blood Glucose Response After Bread Consumption: a Dose-response of Efficacy
This study is designed to identify the minimal effective tested dose of fruit extract consumed with a bread which provides a reduction in venous post-prandial blood glucose compared to a reference bread.
- Trial name
- NCT02388503
- Testing
- no added fruit extract, fruit extract
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Insulin Resistance, Obesity
Adipose Tissue Response to Overfeeding in Insulin Resistance-Prone vs. Insulin Sensitive Humans
Obesity has become an epidemic worldwide. Data from our laboratory and others demonstrate that most of the excess morbidity from obesity is related to insulin resistance (IR).
- Trial name
- NCT02084641
- Testing
- Over feeding
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Stanford University
Glycemic Index and Glycemic Load
Effect of Locally Produced Mango Variety on Glycemic Index
This randomized trial aims to assess the glycemic index (GI) of locally available mango varieties in healthy adult participants, using glucose as the reference food.
- Trial name
- NCT07015827
- Testing
- Mango (langra), mango (chaunsa), MANGO (SINDHRI)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Glucose Metabolism Disorders
Incretin Effects of Branched Chain Amino Acids
Branched chain amino acids (BCAA) are known to exert insulinogenic effect. Whether this effect is mediated by incretins (GLP-1, GIP) is not known. The aim of the study was to show incretin effect of BCAA, i.e.
- Trial name
- NCT02697305
- Testing
- IV BCAA, ORAL BCAA
- Where
- Czechia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Diabetes Mellitus
Microvascular Response in Diabetes Mellitus
Vascular and neurological mechanisms are both likely to be involved in foot ulcer. We recently reported on the hand an original transient pressure-induced vasodilation (PIV) during a 5 mmHg/min increase of pressure strain using…
- Trial name
- NCT00160927
- Testing
- local heating, iontophoresis, actylcholine
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Metabolic Syndrome
Effect of Arabinoxylan and Rye Kernels on Second Meal Responses
Sedentary lifestyles and increasing obesity are main causes of the global increase in the prevalence of the metabolic syndrome (Mets) and type 2 diabetic (T2DM).
- Trial name
- NCT01583270
- Testing
- Arabinoxylan, Rye kernel, Arabinoxylan and rye kernels
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Blood Glucose Response
Glycaemic Response to High REsistant STarch Bread
This study evaluates if the consumption of one sbeIIa/b white bread with high resistant starch content will result in a lower blood glucose response and increased satiety compared with reference white bread.
- Trial name
- REST (NCT04197726)
- Testing
- sbeIIa/b white bread, Control white bread
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Postprandial Glucose Response
Bioequivalence of a Diabetes Specific Tube Feed
Nutricia has a range of nutritionally complete tube feeds on the market including some specific for diabetes patients. A new product is currently under development.
- Trial name
- EQUIDIA (NCT05453838)
- Testing
- oral intake of one serving of the original and new product
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Obesity, Hyperglycemia
A Comparison of Beverages Consumed Within a Meal to Satiation on Meal-time Food Intake and Post-meal Appetite and Glycemic Response in Healthy Young Adults
The objective of the current study is to determine the effects of an ad libitum intake of 1% milk, fruit juice, regular cola, diet cola and water, as part of a pizza meal, on meal food intake, appetite and postprandial blood…
- Trial name
- NCT01595919
- Testing
- Nutritional Intervention
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Overweight, Obesity
Glycaemic Response of Arabic Bread
Bread remains one of the most widely consumed staple foods worldwide, with wheat flour serving as its traditional foundation. However, the widespread dependence on refined wheat-based bread has paralleled the rising prevalence of…
- Conditions
- Overweight, Obesity, Glycaemic Response
- Trial name
- NCT07652320
- Testing
- Control Bread, Chickpea-Enriched Arabic Bread, Pea-Enriched Arabic Bread
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Glycemic Responses
Blood Glucose Response to Test Foods Containing Brewer's Spent Grain
The objective of this project is to determine the impact of incorporating brewers' spent grain into cookie formulations on postprandial blood glucose absorption levels following consumption.
- Trial name
- BSG-PPG (NCT07446179)
- Testing
- Food Intervention
- Where
- Uruguay
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Uruguay
Metabolic Syndrome, Inactivity/Low Levels of Exercise
Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial
This study aims to evaluate the impact of public health interventions on changes in healthy lifestyle habits over time and their subsequent effects on health outcomes.
- Conditions
- Metabolic Syndrome, Inactivity/Low Levels of Exercise, Unhealthy Diet, Unhealthy Alcohol Use
- Trial name
- LifeHealth-RCT (NCT07314957)
- Testing
- Intervention of physical activity, Mediterranean Diet Education, Behavioral: Stress-Resilience Training
- Where
- Croatia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zadar
Type 2 Diabetes, Appetite Regulation
GLycaemic Outcomes With Whey Protein in ageING
The goal of this placebo-controlled, partial crossover design study is to identify the impact of consuming whey protein before meals on free-living glucose control in older adults living with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Appetite Regulation, Whey Protein, Ageing and Geriatric Health
- Trial name
- GLOWING (NCT07285811)
- Testing
- Glycaemic control with whey protein, Glycaemic control with different doses of whey protein
- Where
- 2 sites in United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Obesity, Abdominal, Diabete Type 2
Production of Gut Microbiota-Derived Metabolites in Response to Different Fatty Acid Profiles
The proposed project mainly aims to investigate the microbial processes leading to dietary metabolites production, independently of long-term microbiota adaptation to the diet, by measuring the microbiota-derived metabolite…
- Trial name
- METAc (NCT05917132)
- Testing
- Nutritionnal intervention
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Laval University
Blood Glucose
Blood Glucose Response of Novel Wild Rice Enhanced Food Products (Trial 1)
The goal of this acute double-blind cross over trial is to test the effects of a wild rice cake product compared to products currently on the market on glycaemic control. The main questions it aims to answer are: 1.
- Trial name
- ABWE (NCT06497972)
- Testing
- White bread (control, 32 grams, 14.4 grams of carbohydrate), Brown rice cake, Wild rice (25%) and brown rice (75%) cake
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Dylan MacKay
Glycemic Index of a Meal
Glycemic Response After Palaeolithic-type Meals
The objective of the study is to show post-prandial benefits of Palaeolithic-type meals as compared to a meal constructed along the lines of the WHO dietary recommendations.
- Trial name
- NCT01418573
- Testing
- Palaeolithic meal 1, Palaeolithic meal 2, Reference meal
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unilever R&D