Clinical trials: Glucose Response
Grain-Like Products, Postprandial Glucose
Postprandial Glucose, Insulin and Subjective Saturation Response in Healthy Individuals
This study is a pioneering study in which the effect of the consumption of cakes produced with the addition of cereal-like products such as chia and flax seeds, which have high soluble fiber content, on blood glucose and insulin…
- Conditions
- Grain-Like Products, Postprandial Glucose, Plasma Insulin, Subjective Saturation Response
- Trial name
- NCT05358561
- Testing
- Flaxseed and Chia
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Toros University
Diabetes
Body Composition, Fitness, and Thermoregulation in Young Boys With Type I Diabetes vs. Healthy Soccer Players
The study aims to assess differences in body composition, exercise capacity, and thermoregulation between young soccer players with type 1 diabetes and their healthy peers.
- Trial name
- BCFTYR (NCT06676878)
- Testing
- Incremental exercise
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Paweł Korman
Obesity, Diabetes Mellitus, Type 2
Whole Grains, Gastric Emptying and Glycemic Response
Whole grains have been associated with controlled glycemic response and increased satiety compared to refined grains. However, the properties of whole grains which are responsible for these purported improved health outcomes are…
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Appetitive Behavior
- Trial name
- NCT03467659
- Testing
- Cracked whole wheat porridge, Semolina wheat porridge, Whole wheat flour porridge
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Purdue University
Blood Glucose
Glycemic Response to Wild Rice and Wild Rice Blends in Humans Study
The goal of this clinical trial is to test the effects of wild rice and wild rice blends compared to other rice on glycemic control and evaluating factors that influence glycemic response to wild rice in healthy individuals.
- Trial name
- EFGW (NCT05976633)
- Testing
- Whole white rice (control), Whole brown rice, Whole wild rice
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Sedentary Lifestyle
Cardiovascular Risk in Sedentary Elderly During Prolonged Sitting Time Versus Intermittent Sitting Time
In adults, the sedentary behavior was related to cardiovascular risk markers, regardless of the level of physical activity (PA).
- Trial name
- NCT02894099
- Testing
- Prolonged sitting time, PST+Light intensity Short bouts PA, PST+Moderate intensity Short bouts PA
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Overweight, Insulin Resistance
Effects of Cranberry Powder Supplements on Gut Microbiota Diversity and Metabolic Syndrome
It is of major importance to refine prevention strategies in order to alleviate inflammation, insulin resistance and metabolic syndrome and it appear that improving gut health and microbiota represent a promising strategy.
- Conditions
- Overweight, Insulin Resistance, Microbiota, Endotoxemia
- Trial name
- MICA (NCT03754504)
- Testing
- Cranberry powder
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Laval University
Malnutrition; Diabetes, Malnutrition; Protein
Impact of Pea, Lentil and Oat Flour Particle Size on Glycemic Response in Healthy Adults
The study looks at the comparative effects of food products made with pea, lentil, and oat flour of various particle sizes on postprandial glycemic response, appetite and food intake, and amino acid release in healthy adults.
- Conditions
- Malnutrition; Diabetes, Malnutrition; Protein, Obesity
- Trial name
- PLO (NCT05291351)
- Testing
- Crackers made with whole, coarse, or fine pea and/or wheat flour, Crackers made with whole, coarse, or fine lentil and/or wheat flour, Porridge made with oat flour
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Glycemic Response to Feeding in Healthy Participants
White Rice and Effect of Gellan Gum on Glucose Responses by MRI
Rice is a staple food for over half the world's population. High consumption of white rice has been linked with high obesity and increased risk for type 2 diabetes.
- Trial name
- WIGG (NCT05080400)
- Testing
- White rice, Gellan gum
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sepsis, Hyperglycemia
Gluconeogenesis Rates and Its Precursors in Pediatric Sepsis
Critically ill children have abnormal utilization of nutrients such as glucose, lipids and protein. Often sick children have increased glucose concentrations in blood.
- Conditions
- Sepsis, Hyperglycemia, Critical Illness
- Trial name
- NCT01890928
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Post Bariatricsurgery, Hypoglycemia
Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery
RYGB (roux-en-y gastric bypass) has been reported to reverse type 2 diabetes (T2DM) immediately after surgery before any significant weight loss.
- Trial name
- NCT00992901
- Testing
- Exendin-(9-39), Atropine, GLP-1 and GIP
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Exercise, Healthy Participants
Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial
The goal of this clinical trial is to investigate if blood glucose responses are similar between and within individuals in response to standardized exercise in adults with and without Type 1 diabetes.
- Conditions
- Exercise, Healthy Participants, Glucose Variability, Type 1 Diabetes (T1D)
- Trial name
- NCT07209930
- Testing
- Exercise, Rest
- Where
- Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Overweight, Obesity
Meta-analyses of the Effect of 'Catalytic' Doses of Fructose and Its Epimers on Carbohydrate Metabolism
Despite advances in the prevention and treatment of type 2 diabetes, its prevalence continues to rise worldwide. There is a need for new modalities to improve metabolic control in individuals with type 2 diabetes and those who…
- Conditions
- Overweight, Obesity, Dysglycemia, Prediabetes
- Trial name
- NCT02776722
- Testing
- fructose, allulose, tagatose, or sorbose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Blood Glucose Concentration
The Glycemic and Insulinemic Responses Elicited by Meals Containing Whole Grain Rye Bread or White Wheat Bread
This is a postprandial study with healthy volunteers. The glycemic and insulinemic responses elicited by meals containing either whole grain rye bread or white wheat bread as such or combined with margarine and ham and vegetable…
- Trial name
- NCT02400411
- Testing
- Wheat bread, margarine, ham
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Metformin Response, Fasting Glucose
Dietary Intake of Tryptophan and Metformin Response
This study will examine the influence of dietary intake of tryptophan on response to metformin. The investigators hypothesize that dietary tryptophan alteration will influence metformin response.
- Conditions
- Metformin Response, Fasting Glucose, Tryptophan Concentration, Metformin Concentration
- Trial name
- NCT02184832
- Testing
- Metformin, Low tryptophan diet, High tryptophan diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Glycemic Response
Glucose Response From Antioxidant Rich Potato Chips
Assess impact of potato phytochemical on post-prandial gastric emptying and glucose release from products in a pilot human study.
- Trial name
- NCT02927015
- Testing
- Purple Majesty potato chips, Mountain Rose potato chips, White potato chips
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Purdue University
Normoglycemic, Normal Body Weight
A Study of the Effect of Oats on Post Prandial Glucose Response
The objectives are to assess the effects of high viscosity vs. medium and low viscosity oat β-glucan on post-prandial glycemic response in healthy adult participants.
- Trial name
- NCT02651597
- Testing
- Oatmeal
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Blood Glucose, Satiety Response
Dairy and Vegan Cheese: Effect on Satiety and Blood Glucose
The project will consist of two studies. One study will explore the satiating properties of dairy cheese and its dairy-free substitute when consumed ad libidum, and another study will investigate their effects on postprandial…
- Trial name
- NCT06568497
- Testing
- Food
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mount Saint Vincent University
Healthy
Effect of Brazilian Fruits Peel on Metabolic Regulation and Appetite in Healthy Subjects
The purpose of the study was to investigate how Brazilian fruits peel affect acute/postprandial glucose and insulin responses, inflammatory markers, appetite control peptides, antioxidative capacity, as well as subjective…
- Trial name
- BRASIL-MET (NCT02245906)
- Testing
- Control drink, Brazilian fruit peel flour, Negative control drink
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Lund University
Glucose Metabolism Disorders
Inhibition of the Endogenous GIP Response With a GIP Receptor Antagonist
Delinieation of GIP's effects during an oral glucose tolerance test (OGTT) in humans using GIP receptor antagonisation.
- Trial name
- GA-3 (NCT03133741)
- Testing
- GIP-A, GLP-1 receptor antagonist Exendin[9-39], GIP-A + Exendin[9-39]
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Gestational Diabetes Mellitus (GDM), Type 2 Diabetes (T2DM)
Women With Previous GDM and the Effects of HIIT.
The goal of this clinical trial is to investigate if women with previous gestational diabetes (pGDM) are characterized with unique metabolic and molecular alterations compared to women without pGDM.
- Conditions
- Gestational Diabetes Mellitus (GDM), Type 2 Diabetes (T2DM), High-intensity Interval Training
- Trial name
- GDM-HIIT (NCT07566845)
- Testing
- High-intensity interval training
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital