Clinical trials: Glue Ear
Otitis Media With Effusion (OME), Otitis Media With Effusion in Children
Evaluation of Blowing Exercises Utilizing a Breathing Exercise Device in Otitis Media With Effusion
Otitis media with effusion (OME) is a common condition in which fluid collects behind the eardrum without signs of infection. It can cause hearing problems and discomfort.
- Conditions
- Otitis Media With Effusion (OME), Otitis Media With Effusion in Children, Breathing Exercise
- Trial name
- NCT06967506
- Testing
- Blowing exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Uşak University
Barotrauma;Ear, OME - Otitis Media With Effusion
Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT)
A prospective, multicenter study to evaluate effectiveness and safety of Tymbion iontophoresis and tympanostomy tube placement using the Tula iontophoresis and tube delivery systems for adults in an office setting.
- Conditions
- Barotrauma;Ear, OME - Otitis Media With Effusion, AOM - Acute Otitis Media, Eustachian Tube Dysfunction
- Trial name
- ADEPT (NCT03197558)
- Testing
- Tymbion Iontophoresis and Tube Delivery System (TDS)
- Where
- 8 sites in United States
- Volunteers
- 30 people
- Sponsor
- Tusker Medical
Otitis Media With Effusion
Suitable Method for Routine Diagnostics of EER in Children With Otitis Media With Effusion
The aim of the study was detection of pepsin in effusion in children with OME using Peptest as new quick and cheap method of detection and comparison results with results of other studies in which pepsin was detected by more…
- Trial name
- NCT02183974
- Testing
- Peptest
- Where
- Czechia
- Volunteers
- 44 people
- Sponsor
- University Hospital Ostrava
Otitis Media, Otitis Media With Effusion After Nasopharyngeal Carcinoma
Intranasal Corticosteroid Spray for Preventing Otitis Media With Effusion After Radiotherapy in Nasopharyngeal Carcinoma
This study focuses on a common side effect experienced by many patients after radiation therapy for nasopharyngeal cancer, which is a type of head and neck cancer.
- Conditions
- Otitis Media, Otitis Media With Effusion After Nasopharyngeal Carcinoma, Radiotherapy Side Effects, Radiotherapy Side Effect
- Trial name
- NCT07189572
- Testing
- Triamcinolone Acetonide
- Volunteers
- 168 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Otitis Media With Effusion After Nasopharyngeal Carcinoma
A Prospective, Randomized, Controlled Clinical Study of BET Combined With Tympanostomy Tube Insertion in the Treatment of Intractable OME After Radiotherapy for NPC
The primary purpose of this study is to compare balloon Eustachian tuboplasty (BET) combined with tympanostomy tube insertion and simply tympanostomy tube insertion in the treatment of otitis media with effusion (OME) in…
- Trial name
- NCT05449184
- Testing
- Balloon Eustachian Tuboplasty with Tympanostomy Tube Insertion, Tympanostomy Tube Insertion
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Otitis Media With Effusion
Clinical Study of the Tympanostomy Tube Delivery System
The objective of this investigational study is to evaluate the safety and performance of the Acclarent Tympanostomy Tube Delivery System (TTDS) for the placement of the Tympanostomy Tube [TT(s)] in patients indicated for such…
- Trial name
- inVENT (NCT00939796)
- Testing
- Acclarent Tympanostomy Tube Delivery System
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Integra LifeSciences Corporation
Otitis Media With Effusion
Study of Anti-reflux Medication as a Potential Treatment for Glue Ear in Children
The accumulation of fluid behind the ear drum without any acute inflammation is known as otitis media with effusion (OME). It is the most common cause of acquired hearing loss during childhood.
- Trial name
- NCT01082029
- Testing
- Lansoprazole
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Hamilton Health Sciences Corporation
Otitis Media With Effusion
Study of the Expression of MMPs in OME in Children With Atrophy of the Eardrum
Metalloproteinases (MMPs) constitute a family of endopeptidases that cleaves the extracellular matrix as collagen included in the eardrum. Activity of MMP has been shown in some otitis media with effusion (OME) fluids.
- Trial name
- MMP and OME (NCT03611842)
- Testing
- preservation of mucosal otitis media
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Montpellier
Otitis Media With Effusion
OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
The purpose of this study is to confirm the effectiveness, safety and tolerability of OTO-201 in the treatment of pediatric subjects with bilateral middle ear effusion who require tympanostomy tube placement.
- Trial name
- NCT01949142
- Testing
- OTO-201
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Otonomy, Inc.
Otitis Media With Effusion (OME)
Retrospective Analysis of Perioperative Anesthetic Care and Analgesia Management of Patient Undergoing Bilateral Myringotomy With Tube Insertion
This is a retrospective chart review. The purpose of this study is to retrospectively examine the use of perioperative analgesics on the incidence of postoperative pain and emergence delirium in patients undergoing bilateral…
- Trial name
- NCT02409693
- Testing
- Myringotomy with tube insertion
- Sponsor
- Nationwide Children's Hospital
OME - Otitis Media With Effusion, AOM - Acute Otitis Media
In-Office Tympanostomy Tube Placement in Children (OTTER)
A prospective, single-arm, multicenter study to evaluate effectiveness and safety of Tymbion iontophoresis and tympanostomy tube placement using the Tula Iontophoresis and Tube Delivery Systems for children in an office setting.
- Trial name
- OTTER (NCT03323736)
- Testing
- Iontophoresis & tube placement, Tube placement
- Where
- 19 sites in United States, Canada
- Volunteers
- 370 people
- Sponsor
- Tusker Medical
Middle Ear Effusion, Tympanic Membrane Perforation
PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers to See if it Protects Their Babies From Ear Disease
PneuMum is a randomised controlled trial that aims to find out if pneumococcal vaccination for Australian Indigenous mothers, in the last few months of pregnancy or at delivery, can prevent ear disease in infants.
- Conditions
- Middle Ear Effusion, Tympanic Membrane Perforation, Acute Otitis Media, Pneumococcal Infections
- Trial name
- NCT00310349
- Testing
- 23 valent pneumococcal polysaccharide vaccine
- Where
- Australia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Otitis Media in Children, Cleft Palate Children
Respiratory Tract Microbiome and Probiotics in Children With Cleft Palate
Otitis media with effusion (OME) involves fluid accumulation in the middle ear without infection, sometimes causing discomfort and hearing loss in children.
- Trial name
- NCT06505330
- Testing
- Probactiol Baby
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Antwerp
Otitis Media Effusion, Nasopharyngeal Carcinoma
Distribution of Bacteria in OME After Radiotherapy For NPC.
To observe the prognostic difference of tympanocentesis in different kinds of otitis media effusion.
- Trial name
- NCT06523933
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Chronic Otitis Media With Effusion, Conductive Hearing Loss
Montelukast for Children With Chronic Otitis Media With Effusion (COME): A Double-blind, Placebo-controlled Study
The purpose of our double-blind, placebo controlled study is to test the hypothesis that montelukast therapy might be associated with improved hearing in certain sub populations of children suffering from OME.
- Trial name
- COME (NCT01967498)
- Testing
- Montelukast
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Otitis Media With Effusion, Eustachian Tube Disorder
Novel Imaging of the Eustachian Tube; Patient Study
The purpose of the study is to establish wether a contrast medium applied to the middle ear can be used to diagnose pathology in the auditory tube.
- Trial name
- CT-ET (NCT02282540)
- Testing
- Iodixanol to the Eustachian tube
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Middle Ear Effusion, Otitis Media
Evaluating Laser Otoscope for Middle Ear Effusion Detection
The goal of this cross-sectional diagnostic accuracy investigational study is to learn about the usefulness of laser otoscopy in screening for middle ear fluid.
- Trial name
- NCT07454512
- Testing
- Laser otoscope examination
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- MSTATT LLC
Otitis Media With Effusion
Laser Acupuncture for Otitis Media With Effusion in Children
The goal of this clinical trial is to learn if laser acupuncture (LA) can improve middle ear function and reduce the recurrence of Otitis Media with Effusion (OME) in children.
- Trial name
- NCT07242001
- Testing
- Laser Acupuncture
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Otitis Media With Effusion, Laryngopharyngeal Reflux
Three Methods Used in the Diagnosis of EER in Children With OME
Detection of extraesophageal reflux (EER) in children with chronic otitis media with effusion (OME) using three different diagnostic methods and selection of the group of patients with severe EER who could potentially benefit…
- Trial name
- NCT02183961
- Testing
- Restech, Peptest, Detection of pepsin in adenoid specimen
- Where
- Czechia
- Volunteers
- 24 people
- Sponsor
- University Hospital Ostrava
Otitis Media With Effusion
A Novel Objective Diagnostic Test for Otitis Media With Effusion
Otitis media with effusion (OME) cases refer to a clinically silent condition. Otoscopic findings are subjective and not always reliable. As an objective test tympanometric evaluation is imperfect for diagnosis of OME.
- Trial name
- NCT02179541
- Testing
- RGB
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Nazan Degirmenci