Clinical trials: Gluten Enteropathy
Pancreatic Cancer
Left Celiac Plexus Resection for Pancreatic Cancer at the Body and Tail
This is a prospective study of left celiac plexus resection for pancreatic cancer at the body and tail during standard distal pancreatectomy.
- Trial name
- NCT02117895
- Testing
- Celiac plexus resection, Pancreatectomy
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Fudan University
Primary Sclerosing Cholangitis, Ulcerative Colitis
Gluten-free Diet in PSC and IBD
Primary sclerosing cholangitis (PSC) is a progressive disease of the biliary tree, which represents one of the most frequent indications for orthotopic liver transplantation (OLTx) in developed countries.
- Conditions
- Primary Sclerosing Cholangitis, Ulcerative Colitis, Biliary Tract Diseases, Biliary Disease Tract
- Trial name
- NCT06026449
- Testing
- Gluten-free diet
- Where
- Czechia
- Volunteers
- 51 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Pancreatic Carcinoma Metastatic, Pancreatic Adenocarcinoma
Trial Comparing EUS-guided Radiofrequency Ablation vs. EUS-guided Celiac Plexus Neurolysis
Pancreatic cancer is the second most common gastrointestinal malignancy. Abdominal discomfort is a main symptom in patients with pancreatic cancer. Approximately 75% have pain at diagnosis and over 90% in advanced stages.
- Conditions
- Pancreatic Carcinoma Metastatic, Pancreatic Adenocarcinoma, Pancreatic Neoplasms, Pancreatic Cancer
- Trial name
- NCT03152487
- Testing
- Celiac Plexus Neurolysis, Radiofrequency Ablation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- AdventHealth
Celiac Disease in Children
Assessment of Adherence to Gluten Free Diet in Children and Adolescents by Detection of Gluten in Faecal Samples.
To assess the adherence to gluten free diet by measuring faecal and urinary gluten immunogenic peptides (GIP). This will provide an objective measure for adherence.
- Trial name
- NCT03663309
- Testing
- detecting Gluten peptides in faecal and urine samples
- Where
- Israel
- Volunteers
- 194 people
- Sponsor
- Rabin Medical Center
Diabetes Mellitus, Type 1, Gastroparesis
The Effect of Gluten-free Diet in Type 1 Diabetics With Dyspepsia Symptoms
Patients with type-1 diabetes are more susceptible to motility-related upper gastrointestinal symptoms. Dietary interventions are one of the treatment pillars for these symptoms.
- Conditions
- Diabetes Mellitus, Type 1, Gastroparesis, Dyspepsia, Gluten Sensitivity
- Trial name
- NCT03089632
- Testing
- Gluten-free diet
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Celiac Disease
PTG-100 for Patients With Celiac Disease
The goal of this study is to learn whether or not the drug PTG-100 can reduce or prevent inflammatory injury to the small intestine that occurs when people with celiac disease eat food products containing gluten.
- Trial name
- NCT04524221
- Testing
- PTG-100
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nielsen Fernandez-Becker
Non-celiac Gluten Sensitivity
Gluten and (Extra-)Intestinal Symptoms in NCGS
The goal of this randomized, double-blind, placebo-controlled study is to investigate the effect of expectancy related to gluten consumption versus actual gluten intake on overall GI symptoms in individuals with non-coeliac…
- Trial name
- WoW (NCT05779358)
- Testing
- Expectancy and gluten
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 84 people
- Sponsor
- Maastricht University
Celiac Disease, Ovarian Failure
Can Celiac Disease Affect Ovarian Function in Adolescent?
This case-control multicentre trial was performed from January 1, 2017, to May 31, 2018, in University of Health Sciences Bakirkoy Dr. Sadi Konuk Training and Research Hospital and Hitit University Hospital.
- Trial name
- NCT04024449
- Testing
- Group A
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Chronic Pancreatitis
EUS-guided Celiac Plexus Block vs. Sham in Chronic Pancreatitis
The aim of this randomized trial is to assess the efficacy of EUS-CPB in the alleviation of abdominal pain in patients with chronic pancreatitis.
- Trial name
- EPOCH (NCT06178315)
- Testing
- EUS-guided celiac plexus block
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Orlando Health, Inc.
Celiac Disease
Gut Permeability Assessment in Celiac and Gluten Sensitive Children
This study will assess the effect of gluten on gut barrier function. Investigators at the Mayo Clinic have developed a new gut permeability test using rhamnose (sugar \& water solution), and are hoping to prove its effectiveness…
- Trial name
- NCT02690532
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Celiac Disease
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study
Celiac disease (CD) is a complex disease caused by eating gluten, a protein contained in wheat, rye, and barley. It is well known that many factors contribute to the development of CD, including the genes that you have and the…
- Trial name
- CDGEMM (NCT02061306)
- Where
- 2 sites in United States, Italy
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
Advanced Cancer, Pancreatic Cancer
Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain
This is a prospective, single-arm, pilot feasibility clinical trial designed to evaluate the feasibility and safety of a simulation-free adaptive radiotherapy workflow to enable single-session celiac plexus SBRT planning and…
- Trial name
- Celiac SRS (NCT07636382)
- Testing
- Treatment plan
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University Health Network, Toronto
Celiac Disease in Children
Prevention of Celiac Disease in Skåne
This study aims to investigate the impact of being on a gluten free diet the first three years of life compared to a daily intake of a probiotic supplementation or placebo on the risk of developing celiac disease autoimmunity or…
- Trial name
- PreCiSe (NCT03562221)
- Testing
- Gluten free diet, Probiotics
- Where
- Sweden
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Lund University
Non-celiac Gluten Sensitivity, Anemia
Anemia in Non-celiac Wheat Sensitivity
In recent years, a new gluten- or wheat-related disease has emerged, a condition labelled "non-celiac gluten sensitivity" (NCGS) or "non-celiac wheat sensitivity" (NCWS).
- Trial name
- NCT04377061
- Testing
- Evaluation of anemia
- Where
- 3 sites in Italy
- Volunteers
- 244 people
- Sponsor
- University of Palermo
Celiac Disease, Hypothyroidism
Detection of Celiac Disease in Patients With Hypothyroidism
The study evaluates whether hypothyroid patients requiring elevated doses of levothyroxine to maintain a euthyroid state are at increased risk of having celiac disease.
- Conditions
- Celiac Disease, Hypothyroidism, Celiac Sprue, Malabsorption
- Trial name
- NCT01862510
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Celiac Disease
Treatment of Mild Enteropathy Celiac Disease
The main purpose of this study is to evaluate the natural history of gluten sensitivity in endomysial antibody positive adults with celiac disease suspicion, who were found to have a only mild enteropathy (Marsh I-II) in the…
- Trial name
- TMCD (NCT00628823)
- Testing
- Gluten-free diet
- Where
- Finland
- Volunteers
- 73 people
- Sponsor
- Tampere University Hospital
Celiac Disease
Effectiveness of PENTABIOCEL in Clinical and Laboratory Recovery of Children With Celiac Disease
Celiac disease (CD) is an inflammatory condition of the small intestine. Environmental and genetic factors are involved in the development of CD.
- Trial name
- NCT03857360
- Testing
- Pentabiocel
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Università Politecnica delle Marche
Celiac Disease, Eosinophilic Esophagitis
Improved Diagnostics of Celiac Disease in Children
The main purpose of this study is to improve the diagnostics of celiac disease and reduce the need for invasive endoscopic studies in children.
- Trial name
- NCT02072590
- Where
- 2 sites in Finland, Romania
- Volunteers
- 300 people
- Sponsor
- Tampere University Hospital