Clinical trials: Gluten Intolerance
Pancreatic Cancer
EUS-guided Celiac Plexus Neurolysis for the Treatment of Abdominal Pain in Pancreatic Cancer
Studies have shown that injecting local anesthetics in areas rich in blood vessels increases the risk of drug injection into blood vessels by mistake and increases the systemic absorption of drugs, which may increase the…
- Trial name
- NCT03940027
- Testing
- EUS-guided celiac plexus neurolysis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Changhai Hospital
Intractable Abdominal Pain Secondary to Inoperable Malignancy
EUS-guided CGN for Inoperable Cancer
Patients suffering from pancreatic cancer are associated with a poor prognosis and survival of less than one year is expected in inoperable tumours. Management of these patients would be towards palliation of symptoms.
- Trial name
- NCT02356640
- Testing
- EUS-guided celiac ganglion neurolysis, Percutaneous celiac plexus neurolysis, Olympus UM 2000
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Chinese University of Hong Kong
Non-celiac Wheat Sensitivity
Abdominal Ultrasound Examination in Non-celiac Wheat Sensitivity
Recently it has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have CD or wheat allergy.
- Trial name
- NCT03017274
- Testing
- Abdominal ultrasound examination
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Celiac Disease in Children
Efficacy Assessment of Gluten Free Cupcakes
Randomized controlled trial will be conducted after getting informed consent form from each study participant meeting inclusion criteria (n=70, 35 control group +35 intervention group, 3-8years of age).
- Trial name
- NCT06359613
- Testing
- nutrient rich food product, food product
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Pancreatic Ductal Adenocarcinoma (PDAC)
European Appleby Registry for Pancreatic Cancer
The EURO-APPLEBY Registry is a prospective, multicenter European observational registry designed to characterize contemporary surgical practice and evaluate perioperative and long-term oncological outcomes in patients undergoing…
- Trial name
- EURO-APPLEBY (NCT07889180)
- Volunteers
- 100 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Non-celiac Wheat Sensitivity
Lactose Intolerance and Cow's Milk Protein Allergy in Non-celiac Wheat Sensitivity Patients
In the last few years a new clinical entity has emerged which includes patients who consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease (CD) or…
- Trial name
- NCT03008252
- Testing
- Lactose breath test, DBPC cow's milk protein challenge
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- University of Palermo
Celiac Disease, Small Bowel Mucosal Atrophy or Lesions
AI System for Detection and Characterization of Chronic Enteropathies
Coeliac disease (CD) is an immune-mediated enteropathy leading to small intestinal mucosal atrophy. Diagnosis relies on serology and duodenal biopsies, but it can be complicated by patchy lesions and differential diagnosis with…
- Conditions
- Celiac Disease, Small Bowel Mucosal Atrophy or Lesions, Non-celiac Enteropathies
- Trial name
- NCT07387185
- Where
- Italy
- Volunteers
- 380 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Celiac Disease in Children, Iron Deficiency
Iron Deficiency in Pediatric Celiac Disease: Diet vs. Iron Supplementation Trial
This study aims to understand how to best manage iron deficiency in children newly diagnosed with celiac disease. Many children with celiac disease have low iron levels, even if they do not have anemia.
- Trial name
- NCT06921343
- Testing
- Iron (III) Hydroxide Polymaltose (50 mg/5 mL), Gluten-free diet
- Where
- 5 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Kaplan Medical Center
Celiac Disease, Dermatitis Herpetiformis
Background of Different Phenotypes of Coeliac Disease
The main purpose of this study is to investigate genetic, serological, immunological and microbiata diversities between different coeliac disease phenotypes and to discover applicable prognostic markers for specific phenotypes.
- Trial name
- NCT05597904
- Testing
- Genetic predisposition
- Where
- Finland
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Celiac Disease in Children, Celiac Disease
Experiences of Disclosure in Adolescents With Coeliac Disease
Being diagnosed with coeliac disease means that individuals can no longer consume things containing gluten, such as bread or cake, or they can become very ill.
- Conditions
- Celiac Disease in Children, Celiac Disease, Celiac, Disclosure
- Trial name
- NCT04240340
- Testing
- semi-structured interview
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- University of Oxford
Celiac Disease
Celiac Disease Database
The focus of this study is to create a database containing information about patients with celiac disease. This database will allow us to examine clinical and epidemiologic features of the University of Chicago Medical Center…
- Trial name
- NCT01172665
- Where
- United States
- Volunteers
- 1,090 people
- Sponsor
- University of Chicago
Celiac Disease
Impact of the Diagnosis of Celiac Disease
The main purpose of this study is to assess the impact of the diagnosis of celiac disease on general health, healthcare resource utilization, quality of life and lifestyle.
- Trial name
- NCT01145287
- Where
- Finland
- Volunteers
- 760 people
- Sponsor
- Tampere University Hospital
Disorder of Small Intestine, Gastrointestinal Hemorrhage
European Novel Motorized Spiral Endoscopy Trial
The subject Novel Motorized Spiral Enteroscope (NMSE) represents a new technology which offers all of the advantageous options of spiral enteroscopy with a faster and less invasive approach.
- Conditions
- Disorder of Small Intestine, Gastrointestinal Hemorrhage, Iron Deficiency Anaemia, Crohn's Disease
- Trial name
- ENMSET (NCT02965209)
- Testing
- motorized spiral enteroscopy
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Evangelisches Krankenhaus Düsseldorf
Pancreatic Cancer
Intraoperative Celiac Plexus Neurolysis for Patients With Operable Pancreatic and Periampullary Cancer
Determine if the addition of an intraoperative ethanol celiac plexus neurolysis (alcohol block) in patients undergoing surgical intervention for pancreatic cancer will result in a decrease in cancer associated pain
- Trial name
- NCT00806611
- Testing
- Alcohol Block
- Where
- United States
- Volunteers
- 438 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Chronic Pancreatitis, Pancreatic Cancer
Prospective Study of Celiac Block Injection: 1 vs. 2
The purpose of this prospective randomized study is to compare the clinical effectiveness of EUS-guided CB performed with a single injection versus two injections of medication into the celiac ganglion region.
- Trial name
- NCT00583479
- Testing
- one injection into the celiac ganglion, two injections into the celiac ganglion
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Celiac Disease in Children
Population Study of the Prevalence of Celiac Disease and Other Gluten-dependent Disorders in Children and Adolescents
To study the prevalence and clinical features of celiac disease in children to develop new treatment approaches and rehabilitation strategies.
- Trial name
- NCT04272983
- Where
- Russia
- Volunteers
- 3,070 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Pain, Pancreatic Cancer
Endoscopic Ultrasound (EUS) Guided-Celiac Plexus Neurolysis (CPN) in Unresectable Pancreatic Cancer
The purpose of this study is to examine endoscopic ultrasound guided celiac plexus neurolysis (CPN) with analgesic therapy in patients with unresectable pancreatic cancer as it applies to decreasing the severity of abdominal pain…
- Trial name
- NCT00968175
- Testing
- Ultrasound guided celiac plexus neurolysis (CPN)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Celiac Disease
Celiac Disease Prevention
Celiac disease is an autoimmune disease induced by wheat gluten. Destruction of epithelial cells and microvilli on gut mucosa is causing a "flat mucosa" and an absorption defect.
- Trial name
- NCT00617838
- Testing
- Optimal gluten introduction
- Where
- Finland
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Celiac Disease
Wheat Flour Treatment With Microbial Transglutaminase and Lysine Ethyl Ester: New Frontiers in Celiac Disease Treatment.
Celiac disease is one of the most common forms of food intolerance (prevalence 1/200). The disease occurs in genetically predisposed individuals after ingestion of foods containing gluten.
- Trial name
- WHETMIT (NCT02472119)
- Testing
- rusks made of wheat flour enzymatically treated, rusks made of wheat flour not enzimatically modified, Gluten-free diet
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Roma La Sapienza
Celiac Disease
Assessment of Coeliac Disease in Patients With Type 2 Diabetes
This study aims to screen and diagnose coeliac disease in patients with type 2 diabetes and monitor the effect of gluten-free diet on the metabolic status
- Trial name
- NCT06283264
- Volunteers
- 100 people
- Sponsor
- Assiut University