Clinical trials: Gluten-Sensitive Enteropathy
Celiac Disease
Gluten Challenge in Celiac Disease
Up till 30 participants with celiac disease on a glutenfree diet are asked to consume gluten containing cookies or bread for 3 days. Questionnaires and sampling of blood is done before, during and after.
- Trial name
- NCT02464150
- Testing
- Gluten challenge
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- Oslo University Hospital
Celiac Disease in Children
Dietary Intervention Using a Gluten-free App to Improve Tracking, Adherence, and Learning(DIGITAL) Study
With rising incidence of celiac disease(CeD) (3% of population), there is an urgent need for practical, efficient and usable application that can feedback to families and providers about their ultra-processed gluten-free food…
- Trial name
- DIGITAL (NCT07192874)
- Testing
- MyMedDiary, Feedback on Gluten Exposure
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Celiac Disease, Diabetes Mellitus, Type 1
Celiac Disease and Diabetes- Dietary Intervention and Evaluation Trial
Currently no consensus exists on the optimal way to manage asymptomatic patients with celiac disease (CD) and Type 1 diabetes (T1D).
- Trial name
- CD-DIET (NCT01566110)
- Testing
- Gluten Free Diet
- Where
- 7 sites in Canada
- Volunteers
- 50 people
- Sponsor
- The Hospital for Sick Children
Celiac Disease
Capsule Endoscopy in Newly Diagnosed Patients of Celiac Disease
Celiac Disease is an autoimmune disorder that affects approximately 1% of the world's population 1. The diagnosis of CD requires clinical, histopathological and serological factors 2.
- Trial name
- NCT03731806
- Where
- Pakistan
- Sponsor
- Tazeen Rasheed
Celiac Disease, Autoimmune Enteropathy
Pathogenic Study of Adult Immune Enteropathies
The study focuses the mechanisms underlying the loss of intestinal homeostasis in celiac disease, refractory celiac disease and other immune diseases such as monogenic enteropathy, inflammatory bowel diseases or drug induced…
- Conditions
- Celiac Disease, Autoimmune Enteropathy, Inflammatory Bowel Diseases
- Trial name
- ENTEROPATH (NCT04280510)
- Testing
- Blood sample collection; gastrointestinal biopsy
- Where
- 4 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Abdominal Pain
Efficacy Study of Acupuncture to Treat the Upper Abdominal Pain of Cancer Patients
This study is to investigate the effectiveness of acupuncture for alleviating the upper abdominal pain of cancer patients
- Trial name
- NCT01913574
- Testing
- Acupuncture, Neurolytic celiac plexus block (NCPB)
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Daegu Catholic University Medical Center
Coeliac Disease, Celiac Disease in Children
Validation of the CDAT in the Polish Paediatric Population
The English version of the Celiac Dietary Adherence Test (CDAT) will be translated into Polish using the "forward-backwards-forward" translation model, with the author's consent (already obtained by the applicants).
- Trial name
- CD-PL-CDAT (NCT07142148)
- Testing
- CDAT - phase 1, CDAT - phase 2
- Volunteers
- 20 people
- Sponsor
- Medical University of Warsaw
Unidentified Gastrointestinal Symptoms Following Gluten-free Oats Consumption
Gluten-free Oats and Gastrointestinal Health in Coeliac Disease, Part 1
The research aims to investigate the effects of gluten-free oats to the gastrointestinal health in celiac disease patients and healthy subjects.
- Trial name
- NCT02764931
- Testing
- Gluten free oats and gastrointestinal health
- Where
- Finland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Turku
Celiac Disease
Evaluation of Patient Reported Outcome Instruments in Celiac Disease Patients
This is an evaluation of celiac-specific patient reported outcome instruments in celiac disease patients.
- Trial name
- NCT01560169
- Where
- 10 sites in United States, Canada
- Volunteers
- 110 people
- Sponsor
- Alvine Pharmaceuticals Inc.
Type 2 Diabetes Mellitus, Celiac Disease
Fiber-enriched Buckwheat Pasta and Glucose Variability in Patients With Type 1 Diabetes and Celiac Disease
The intervention was preceded by a 1-week run-in period during which participants underwent continuous glucose monitoring (CGM) and filled in a 7-day dietary record to optimize basal infusion rate and insulin-to-glycemic load…
- Trial name
- NCT03380988
- Testing
- Acute test meal with fiber-enriched buckwheat pasta, Acute test meal with corn pasta
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Federico II University
Non Celiac Gluten Sensitivity
Prevalence of Non Celiac Gluten Sensitivity Among Patients Spontaneously Adherent to Gluten Free Diet
The purpose of this study is to assess the prevalence of Gluten Sensitivity, by a double-blind placebo-controlled challenge with gluten, followed by two months period of Low-FODMAPs (Fermentable Oligosaccharides Disaccharides…
- Trial name
- NCT01827566
- Testing
- gluten, gluten free flour
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Università degli Studi di Brescia
Celiac Disease
A Study of TAK-062 in Treatment of Active Celiac Disease in Participants Attempting a Gluten-Free Diet
The main aim is to see how TAK-062 works to reduce celiac-related symptoms and improve small intestinal damage due to gluten exposure, in participants with celiac disease (CeD) attempting to maintain a gluten-free diet (GFD) in…
- Trial name
- NCT05353985
- Testing
- TAK-062, Simulated Inadvertent Gluten Exposure (SIGE) Gluten-Bar, Simulated Inadvertent Gluten Exposure (SIGE) Gluten-free Bar
- Where
- 102 sites in United States, Belgium and 6 more
- Volunteers
- 153 people
- Sponsor
- Takeda
Celiac Disease
Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity
The disappearance of intestinal parasites from humans in developed countries may be responsible for the upsurge in many diseases including Celiac Disease, Crohn's, ulcerative colitis, asthma and hay fever.
- Trial name
- NCT00671138
- Testing
- Necator americanus
- Where
- 3 sites in Australia
- Volunteers
- 20 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
Celiac Disease in Children, Intussusception
Clinical Association Between Celiac Disease and Intussusception in Children
Clinical association Between Celiac Disease and Intussusception in children
- Trial name
- Celiac (NCT06914024)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- merna hamdy kamal mohammed
Celiac Disease
Prebiotic as a Supplement of Gluten-free Diet in the Management of Celiac Disease in Children
Prebiotics are known as substances affecting beneficially the organism by restoring the intestinal microbiota balance, stabilizing the intestinal barrier and modulating the endocrine and immune functions.
- Trial name
- NCT03064997
- Testing
- Synergy 1
- Where
- 2 sites in Poland
- Volunteers
- 34 people
- Sponsor
- Polish Academy of Sciences
Pancreatic Cancer
EUS-guided Celiac Plexus Neurolysis for the Treatment of Abdominal Pain in Pancreatic Cancer
Studies have shown that injecting local anesthetics in areas rich in blood vessels increases the risk of drug injection into blood vessels by mistake and increases the systemic absorption of drugs, which may increase the…
- Trial name
- NCT03940027
- Testing
- EUS-guided celiac plexus neurolysis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Changhai Hospital
Intractable Abdominal Pain Secondary to Inoperable Malignancy
EUS-guided CGN for Inoperable Cancer
Patients suffering from pancreatic cancer are associated with a poor prognosis and survival of less than one year is expected in inoperable tumours. Management of these patients would be towards palliation of symptoms.
- Trial name
- NCT02356640
- Testing
- EUS-guided celiac ganglion neurolysis, Percutaneous celiac plexus neurolysis, Olympus UM 2000
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Chinese University of Hong Kong
Non-celiac Wheat Sensitivity
Abdominal Ultrasound Examination in Non-celiac Wheat Sensitivity
Recently it has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have CD or wheat allergy.
- Trial name
- NCT03017274
- Testing
- Abdominal ultrasound examination
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Celiac Disease in Children
Efficacy Assessment of Gluten Free Cupcakes
Randomized controlled trial will be conducted after getting informed consent form from each study participant meeting inclusion criteria (n=70, 35 control group +35 intervention group, 3-8years of age).
- Trial name
- NCT06359613
- Testing
- nutrient rich food product, food product
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Pancreatic Ductal Adenocarcinoma (PDAC)
European Appleby Registry for Pancreatic Cancer
The EURO-APPLEBY Registry is a prospective, multicenter European observational registry designed to characterize contemporary surgical practice and evaluate perioperative and long-term oncological outcomes in patients undergoing…
- Trial name
- EURO-APPLEBY (NCT07889180)
- Volunteers
- 100 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili