Clinical trials: Glycemic Control
Type2 Diabetes, Cardiovascular Diseases
Peanuts and Glycemic Control
A two-period randomized crossover study will be conducted to determine the effect of peanuts on glycemic control, and elucidate the role of the microbiome in glucose regulation, in individuals with impaired fasting glucose.
- Trial name
- NCT03654651
- Testing
- Peanut, High carbohydrate snack
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Penn State University
Postprandial Glycemic Response
A Study to Investigate the Effect of SFF on Glucose and Insulin Responses
This goal of this clinical study is to investigate the postprandial glycemic and insulinemic response in healthy adults after the consumption of: 1. Sugars from Fiber in comparison with dextrose 2.
- Trial name
- NCT05587426
- Testing
- SFF, Glucose, SFF chocolate chips
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge Glycoscience
Type II Diabetes
The Effects of Raspberry Leaf Tea on Blood Glucose Control
The aim of the present clinical trial is to assess how raspberry leaf polyphenols impact on postprandial glucose and insulin levels in healthy individuals consuming sucrose.
- Trial name
- RLT (NCT06385626)
- Testing
- Raspberry leaf tea
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Reading
Quality of Life, Type 2 Diabetes
Monitoring Parameters Beyond Glycemic Control: Impact of Sitagliptin on Quality of Life in Type 2 Diabetes Patients
Scarcity of local patients' quality of life data assessing diabetes treatment led us design a protocol to assess improvement in the quality of life of patients with Type II Diabetes mellitus.
- Conditions
- Quality of Life, Type 2 Diabetes, Metformin+Sitagliptin
- Trial name
- DQOL (NCT05167513)
- Testing
- Metformin / Sitagliptin Oral Tablet
- Where
- Pakistan
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Getz Pharma
Healthy Volunteers
Effect of Three Fibres on Glycaemic and Insulinaemic Responses in Healthy Adult Volunteers
The purpose of this study is to determine whether DuPont Experimental Dietary Fibre products 1 and 2 are digested using glycaemic and insulinaemic response as markers.
- Trial name
- NCT02701270
- Testing
- Experimental Dietary Fibre 1, Experimental Dietary Fibre 2, Polydextrose
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Danisco
Healthy
Glycemic and Metabolic Responses of Frozen Yogurt Containing Saskatoon Berry Powder in Healthy Males and Females
A single site, blinded, randomized, controlled study designed to examine the glycemic and metabolic response of frozen yogurt containing Saskatoon berry powder in healthy males and females.
- Trial name
- NCT02571114
- Testing
- Saskatoon Berry Frozen Yogurt, Frozen Yogurt, Control 1
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Type 2 Diabetes Mellitus
A Study of MK-0893 on Glucagon-Induced Glycemic Excursion in Healthy Male Participants Following Intravenous Administration of Glucagon, Sandostatine® and Insulin (MK-0893-002)
This is a study to assess the pharmacokinetics, safety, and tolerability of sequential single oral doses of MK-8093 10 mg, 40 mg, 200 mg, or placebo to MK-8093 (Part 1) depending on treatment assignment in young healthy male…
- Trial name
- NCT02012166
- Testing
- MK-0893 10 mg, MK-0893 40 mg, MK-0893 200 mg
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Glycemic Response
Assessment of the Glycemic Responses to Nutritional Products
This study assesses the glycemic responses to nutritional products. During a study visit fasted subjects will consume one serving of the reference product or the test product.
- Trial name
- GLIN#1 (NCT05179031)
- Testing
- First Reference product (dextrose, containing 25 g of carbohydrates), Second Reference product (dextrose, containing 25 g of carbohydrates), Third Reference product (dextrose, containing 25 g of carbohydrates)
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Metabolic Disease, Diabetes
Dietary Protein Sources and Glycemic Variability
This goal of trial is to evaluate the effects of plant-based vs. animal-based diets on glycemic variability in overweight or obese adults through a 3-week dietary intervention.
- Conditions
- Metabolic Disease, Diabetes, Overweight, Obesity
- Trial name
- ProG (NCT06525441)
- Testing
- Plant-based Diet, Animal-based Diet
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Normoglycemia, T2DM (Type 2 Diabetes Mellitus)
To Study the Effects of Mango Ingestion in T2DM and Non-diabetic Subjects.
T2DM patient will be recruited from endocrine OPD 1. Clinical History and Examination: 1. General Physical Examination: Height (cm) weight (kg) BMI (kg/m2) Blood Pressure (mmHg) 2.
- Trial name
- NCT06055582
- Testing
- Bread, Mango
- Where
- India
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Prediabetes
Exploring Unconventional Plant-Derived Metabolites for Glycemic Control: the Case of Pomegranate
The EXPLORER study will investigate whether supplementation with a pomegranate extract rich in ellagitannins is able to improve well-being and metabolic health in individuals without diabetes.
- Trial name
- EXPLORER (NCT06659523)
- Testing
- EPS supplement intervention
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Regina Menezes
Prediabetic State
RCT of a Polyherbal Dietary Supplement for Prediabetes
The primary purpose of this study is to evaluate the impact of a polyherbal dietary supplement (Designs for Health - GlucoSupreme™ Herbal) on markers of glycemic control and other structure/function outcomes among a sample of…
- Trial name
- NCT03388762
- Testing
- GlucoSupreme™ Herbal
- Where
- 4 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Brain Activity, Appetite
Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol
The objectives of the research are to assess the effects of increased protein and fiber intake at breakfast on neural activation in brain regions associated with appetitive drive and reward-driven eating, measures of subjective…
- Conditions
- Brain Activity, Appetite, Ingestive Behavior, Glucose Control
- Trial name
- PFB (NCT02169245)
- Testing
- Dietary control of protein and fiber intake at breakfast
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Diabetes, Type 1 Diabetes
Behavioral Economic Incentives to Improve Glycemic Control Among Adolescents and Young Adults
In this study the investigators will compare a novel approach using daily financial incentives and a tiered sponsor network to motivate adolescents and young adults with type 1 diabetes to improve glycemic control.
- Trial name
- NCT02568501
- Testing
- Daily feedback, Financial incentive
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Appetite
Cereal-based Products Fortified With Legumes and Effects on Glycemic Control and Appetite Regulation
Legumes are rich source of proteins and dietary fibers which are associated with satiety and amelioration of postprandial glycemic response.
- Trial name
- NCT03974165
- Testing
- Cereal-legume product 1, Cereal-legume product 2, Cereal product
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Type 1 Diabetes Mellitis, Cognition
Glycemic Control, Brain Structure and Cognition in Youth With Type 1 Diabetes (T1DM)
LO5 study: The investigators are inviting a new group of youth (ages 7-16) who have been recently diagnosed with type 1 diabetes and their non-diabetic siblings.
- Trial name
- LO5/HY5 (NCT00879203)
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Glycemic Response, Insulinemic Response
Glycemic and Insulinemic Impact of a Test Granola 2 Versus a Control Granola
The objectives of this study are to examine the blood glucose and serum insulin response elicited by servings of Test Granola and Control Granola containing equal amounts of available carbohydrate over a 3 h time period.
- Conditions
- Glycemic Response, Insulinemic Response, Subject Hunger Response
- Trial name
- NCT03493022
- Testing
- Test Granola, Control Granola
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Type 1 Diabetes Mellitus
Medtronic 670G Insulin Pump and the Impact on Glycemic Control, Quality of Life, and Compliance
Analyze the Medtronic 670g pump on glycemic control
- Trial name
- NCT04329871
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Metabolic Research Institute, Inc.
Glycemic Control, Subjective Appetite
Sugars-sweetened Beverages and Exercise on Glycaemic Response and Subjective Appetite in Children
The purpose of the study is to understand the role chocolate milk compared to a fruit drink, with and without exercise, on glycaemic regulation and subjective appetite in children.
- Trial name
- NCT02197195
- Testing
- Chocolate Milk, Fruit Drink, Exercise
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Diabetes
A Randomized Trial of an Intensive Education Intervention Using a Network of Involved Diabetic Patients (Peer Educators) to Improve Glycemic Control of Type 2 Diabetic Patients
The project will test the implementation of a specific methodology for education of type 2 diabetic patients that will be set up using patients involved (peer educators) and 3 guides developed specifically for the therapeutic…
- Trial name
- NCT01485913
- Testing
- intensive education intervention using a network of involved diabetic patients (peer educators)
- Where
- Mali
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Sante Diabete Mali