Clinical trials: Glycemic Control for Diabetes Mellitus
Gestational Diabetes, Type2 Diabetes
iGlucose® Remote Patient Monitoring Device as an Adjunct to Routine Glucose Meter Devices for Glycemic Management and Control in Gestational Diabetes
The purpose of this study is to investigate whether automation of glucose monitoring data to facilitate the total number of recommended and completed SMBG checks improve clinical outcomes for women living with gestational and…
- Conditions
- Gestational Diabetes, Type2 Diabetes, Pregnancy in Diabetic
- Trial name
- iGlucose (NCT04206748)
- Testing
- iGlucose Smart Meter System, Routine Care-RX meter
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Type 2 Diabetes
Fotonovela for Type 2 Diabetes Mellitus
Diabetes with poor sugar control can lead to blindness, heart attacks, and amputations. Latinos are more at risk for diabetes. A fotonovela is a type of comic book commonly read by Latinos that might be a way to teach them about…
- Trial name
- NCT00472095
- Testing
- Fotonovela
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Type 2
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Basal Insulin +/- Sulfonylurea (GETGOAL-L-ASIA)
The purpose of this study is to evaluate the benefits and risks of lixisenatide (AVE0010), in comparison to placebo, as an add-on treatment to basal insulin with or without sulfonylurea, over a period of 24 weeks of treatment.
- Trial name
- GETGOAL-L-ASIA (NCT00866658)
- Testing
- Lixisenatide (AVE0010), Pen auto-injector, Sulfonylurea
- Where
- 4 sites in Japan, Philippines and 2 more
- Volunteers
- 311 people
- Sponsor
- Sanofi
Diabetes, Gestational, Diabetes, Type 2
Glycemic Control Using Insulin Levemir Versus Insulin NPH for Diabetes in Pregnancy
The aim of this study is to compare glycemic control in pregnant women treated with insulin Detemir and pregnant women treated with NPH insulin.
- Trial name
- NCT01837680
- Testing
- Insulin
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Primary Hyperparathyroidism, Type 2 Diabetes
Glycemic Control, Type II Diabetes, Parathyroidectomy
The purpose of this study is to assess glycemic control after parathyroidectomy in patients with primary hyperparathyroidism and concomitant type 2 diabetes mellitus.
- Trial name
- NCT05761743
- Testing
- Urine and Blood Test
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Cleveland Clinic
Type 1 Diabetes
New Strategies for Postprandial Glycemic Control Using Insulin Pump Therapy
Achieving near-normoglycemia has been established as the main objective for most patients with type 1 diabetes (T1DM). However, insulin dosing is an empirical process and its success is highly dependent on the patients' and…
- Trial name
- NCT01550809
- Testing
- iBolus, tBolus (traditional bolus)
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Diabetes Mellitus, Type 2, Insomnia
The Impact of Cognitive Behavioral Therapy for Insomnia (CBT-I) on Glycemic Control in Older Type 2 Diabetes (T2D) Comorbid With Insomnia
This study is a RCT aiming to use CBT-I as intervention, compared to usual care as control, to elucidate the effect of CBT-I on glycemic control, sleep quality, psychological outcomes, and cognitive function in Hong Kong Chinese…
- Trial name
- NCT04831385
- Testing
- Cognitive Behavioural Therapy
- Where
- Hong Kong
- Volunteers
- 214 people
- Sponsor
- Chinese University of Hong Kong
Diabetes Mellitus, Type 2
Evaluation of a 4mmx32G Pen Needle for Injection of Basal Insulin Doses Above 40 Units
The primary purpose of this study is to demonstrate that the BD 4mm x 32G Ultra-Fine Nano pen needle provides equivalent glycemic control to the BD 8mm x 31G Ultra-Fine short pen needle as measured by fructosamine (FRU) among…
- Trial name
- NCT01334606
- Testing
- 4 mm x 32G pen needle (Nano), 8mm x 31G pen needle (Short)
- Where
- 3 sites in United States, Canada
- Volunteers
- 21 people
- Sponsor
- Becton, Dickinson and Company
Maternal Cardiometabolic Health, Molecular Impact of Psychological Stress and Socioeconomic Adversity
Conscious Pregnancy: Supporting Maternal Cardiometabolic Health With Mindfulness
A pilot randomized control trial (RCT) to examine the efficacy of a culturally tailored mindfulness intervention upon fasting cardiometabolic factors (including markers of glycemic control) and inflammatory gene expression in…
- Conditions
- Maternal Cardiometabolic Health, Molecular Impact of Psychological Stress and Socioeconomic Adversity, Maternal Inflammatory Markers, Maternal Diabetes
- Trial name
- NCT06898658
- Testing
- Mindfulness Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Type2 Diabetes Mellitus
Financial Incentives for Low Socioeconomic Diabetic Patients
Patients with uncontrolled diabetes [glycated hemoglobin (Hba1c)>8.5%] from low socioeconomic status neighborhoods in Jerusalem will be recruited. They will be randomly assigned to an intervention group and a control group.
- Trial name
- NCT03506230
- Testing
- Incentives
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Clalit Health Services
Type 2 Diabetes Mellitus, Hypertension
Technology-augmented Self-monitoring Model Among Patients With Type 2 Diabetes and Hypertension
Objective: To develop and evaluate a technology-augmented self-monitoring model using a randomized controlled trial to demonstrate whether patients with co-morbid type 2 diabetes mellitus and hypertension can improve their…
- Trial name
- NCT02799953
- Testing
- Technology-based self-management model
- Where
- China
- Volunteers
- 299 people
- Sponsor
- The University of Hong Kong
Cgm, Gestational Diabetes
Real-time Continuous Glucose Monitoring for Reduced Adverse Complications and Events in Women With Gestational Diabetes (GRACE): a Multicentre International Randomized Controlled Trial
Real-time continuous glucose monitoring (CGM) systems provide users with information about current glucose levels and alert the patient before the upper or lower glucose threshold is reached or when glucose levels change rapidly.
- Conditions
- Cgm, Gestational Diabetes, Pregnancy Complications, Blood Glucose
- Trial name
- GRACE (NCT03981328)
- Testing
- Dexcom G6 Continuous Glucose Monitoring System, self-monitored blood glucose
- Where
- Austria
- Volunteers
- 375 people
- Sponsor
- Medical University of Vienna
Diabetes Mellitus, Type 2
Lifestyle and Glucose Lowering Medication in T2DM
This study evaluates the effect of a lifestyle intervention maintenance of glycemic control while reducing glucose lowering drugs in patients with type 2 diabetes mellitus.
- Trial name
- NCT02417012
- Testing
- U-TURN, Standard care
- Where
- Denmark
- Volunteers
- 97 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Type 2 Diabetes Mellitus
Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260)
The purpose of this study is to examine the insulin-sparing effect of sitagliptin 100 mg once-daily compared with placebo over 24 weeks in participants with type 2 diabetes mellitus who have inadequate glycemic control on insulin…
- Trial name
- NCT01462266
- Testing
- Sitagliptin, Insulin Glargine, Metformin
- Volunteers
- 660 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes, Diabetes Mellitus, Type 2
Observational Study on Blood Glucose Control in Patients With Diabetes Using Modern Insulin
This study is conducted in Europe. An observational study evaluating the blood glucose control in patients using a modern insulin: NovoRapid®, NovoMix® 30 or Levemir® for treatment of Type 2 diabetes mellitus in Czech Republic.
- Trial name
- NCT00670722
- Testing
- insulin aspart, insulin detemir, biphasic insulin aspart 30
- Where
- Czechia
- Volunteers
- 6,500 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus
RED BEAN AND TOMATO SNACK BAR FORMULATIONS AS A HEALTHY SNACK FOR DIABETES MELLITUS PATIENTS
The goal of this clinical trial is to develop a "GlycoBite" snack bar formulation combination of red beans and tomatoes, and to assess its acceptability, nutritional content, and effectiveness on blood glucose levels in diabetic…
- Trial name
- NCT07255170
- Testing
- The GlycoBite snack bar formula created is to combine tomatoes and red beans in a ratio of 60% and 40% respectively. Participants consuming 40 grams of "GlycoBite" snack bars daily
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- University Ngudi Waluyo
Diabetes Mellitus, Type 1 Diabetes
Medtronic Treat to Range (TTR) Closed-Loop Control
The purpose of this study is to evaluate a treat-to-range automated insulin management system using continuous glucose monitoring (CGM) and subcutaneous insulin pump infusion in individuals with type 1 diabetes.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Metabolic and Nutritional Disorders
- Trial name
- NCT01490151
- Testing
- TTR controller (Medtronic)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Stanford University
Diabetes Mellitus, Type 1, Continuous Glucose Measurement
Individualized Automatic Coaching Message for Glycemic Management and Depressive Symptom
This is a single-center, randomized, prospective, confirmatory study of efficacy of individualized automatic coaching message for glycemic management and depressive symptom in patients with type 1 diabetes.
- Trial name
- NCT06684678
- Testing
- individualized automatic coaching message for glycemic management and depressive symptom
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Samsung Medical Center
Type 1 Diabetes
Timing of Meal Insulin Boluses for Optimal Postprandial Glycemic Control in Type 1 Diabetes
Blood glucose levels in patients with type 1 diabetes tend to peak after eating a meal due to the delayed action of insulin when compared to carbohydrate absorption from food.
- Trial name
- NCT01693302
- Testing
- Insulin
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Non-Insulin-Dependent
MK0431/ONO-5435 Phase III Clinical Trial -Add-on to Voglibose Study for Patients With Type 2 Diabetes Mellitus (MK0431-104)
The phase III clinical trial examines the efficacy, safety, and tolerability of the addition of MK0431/ONO-5435 to Japanese patients with type 2 diabetes mellitus (T2DM) who have inadequate glycemic control on diet/exercise…
- Trial name
- NCT00837577
- Testing
- Sitagliptin, Voglibose
- Volunteers
- 133 people
- Sponsor
- Merck Sharp & Dohme LLC