Clinical trials: Gonarthrosis; Primary, Bilateral
Knee Osteoarthritis
Population Pharmacokinetics of Ropivacaine
The aim of this study was to investigate the pharmacokinetics of free and total ropivacaine after unilateral and bilateral TKA. A population model was successfully built and peak free ropivacaine concentration stayed below…
- Trial name
- NCT04702282
- Testing
- ropivacain concentration measurements
- Volunteers
- 28 people
- Sponsor
- Hvidovre University Hospital
Gonarthrosis; Primary
Radiologic Results of One-Stage Bilateral TKR - One Surgeon Sequential vs. Two Surgeon Simultaneous: A Randomized Controlled Study
Many surgeons and patients prefer bilateral total knee arthroplasty (TKA) under one anesthesia as single-stage administration. A single-stage bilateral TKA can be performed in two different ways: single-stage, two-team…
- Trial name
- NCT04434690
- Testing
- Simultaneous bilateral total knee arthroplasty, Sequenced bilateral TKA
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bezmialem Vakif University
Gonarthrosis; Primary, Gonarthrosis
Comparison of Multiradius and Singleradius Total Knee Arthroplasty
The Investigators would like to compare multiradius and single-radius total knee arthroplasty using with association between sagittal patellar offset and anterior knee pain in subjects having undergone bilateral total knee…
- Conditions
- Gonarthrosis; Primary, Gonarthrosis, Gonarthrosis; Primary, Bilateral, Knee Osteoarthritis
- Trial name
- NCT04364971
- Testing
- singleradius and multiradius total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 494 people
- Sponsor
- Bezmialem Vakif University
Bilateral Total Knee Arthroplasty, Gonarthrosis; Primary, Bilateral
Bilateral Simultaneous Total Knee Arthroplasty for Bilateral Gonarthrosis
The effects of two-team and single-team simultaneous bilateral total knee arthroplasty (SBA) on peri- and postoperative complications are not clear.
- Trial name
- NCT04299516
- Testing
- Two-team simultaneous bilateral total knee arthroplasty, Single-team simultaneous bilateral total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 246 people
- Sponsor
- Bezmialem Vakif University
Bilateral Primary Osteoarthritis of Knee
Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis
The overall goal of this study is to develop regenerative cell therapy for use in patients with osteoarthritis (OA). The primary objective of this proposal is to conduct a pilot study that assesses the safety and feasibility of…
- Trial name
- BMAC (NCT01931007)
- Testing
- Autologous Bone Marrow Aspirate Concentrate, Sterile saline
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gonarthrosis; Primary, Varus Gonarthrosis
Safety of Bilateral HTO: One-Stage vs.Two-Stage: A Randomized Controlled Study
In this study, bilateral simultaneous high tibial osteotomy (HTO) was compared with staged bilateral HTO in terms of complications.
- Trial name
- NCT04399304
- Testing
- simultaneous bilateral high tibial osteotomy, Staged bilateral high tibial osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Bezmialem Vakif University
Total Knee Anthroplasty, Osteoarthritis(Primary)
COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty
Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA.
- Conditions
- Total Knee Anthroplasty, Osteoarthritis(Primary), Osteoarthritis (OA) of the Knee, Bilateral Knee Osteoarthritis
- Trial name
- COSTI (NCT06809998)
- Testing
- Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL)., Band-Aid
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Primary Gonarthrosis, Bilateral, Knee Osteoarthritis
Association Between Sagittal Patellar Offset and Anterior Knee Pain in Total Knee Arthroplasty
The aim of this study to evaluate whether the position of the sagittal patellar offset is a predictive factor for anterior knee pain in subjects having undergone bilateral multiradius total knee replacement.
- Conditions
- Primary Gonarthrosis, Bilateral, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT04353440
- Volunteers
- 80 people
- Sponsor
- Bezmialem Vakif University