Clinical trials: Gonorrhea
Sexually Transmitted Diseases, Bacterial, Syphilis
Superiority of On-demand PrEP Versus PEP on Using Doxycycline for Preventing STI in MSM
The goal of this clinical trial is to compare the effectiveness of doxycycline taken for on-demand pre-exposure prophylaxis (DoxyODPrEP) and its post-exposure use (DoxyPEP) in preventing bacterial sexually transmitted infections…
- Conditions
- Sexually Transmitted Diseases, Bacterial, Syphilis, Gonorrhea, Chlamydia
- Trial name
- NCT06188442
- Testing
- DoxyODPrEP, DoxyPEP
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Sexually Transmitted Infection, Gonorrhea Female
Use of a Rapid Test for Gonorrhea & Chlamydia for Women Presenting With Possible Sexually Transmitted Infections
The purpose of this study is to evaluate the effect of utilizing a rapid turnaround CT/NG test on treatment of female patients in the emergency department or urgent care setting with possible STIs.
- Conditions
- Sexually Transmitted Infection, Gonorrhea Female, Chlamydia Females
- Trial name
- NCT03098394
- Testing
- Cepheid Xpert CT/NG Rapid Turnaround Test, Polymerase chain reaction (PCR)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Chlamydia Trachomatis Infection, Gonorrhea
Check it: A New Approach to Controlling Chlamydia Transmission in Young People
This study, named "Check it," is a bundled program for African American (AA) men ages 15-24 that includes community testing for chlamydia and gonorrhea, expedited treatment for subjects who test positive and their female sexual…
- Trial name
- NCT03098329
- Testing
- Ct/GC screening
- Where
- United States
- Volunteers
- 1,907 people, healthy volunteers welcome
- Sponsor
- Tulane University
Chlamydia Infections, Gonorrhea
Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays
The objective of this study is to obtain female first-catch urine, vaginal, cervical and endocervical swabs for testing with multiple APTIMA Assays on the Gen-Probe PANTHER® and TIGRIS® Systems.
- Conditions
- Chlamydia Infections, Gonorrhea, Trichomonas Infections
- Trial name
- NCT01728103
- Testing
- APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays
- Where
- 14 sites in United States
- Volunteers
- 1,336 people, healthy volunteers welcome
- Sponsor
- Gen-Probe, Incorporated
Sexually Transmitted Infections
STI/HIV Intervention Behavioral Intervention Program
The hypothesis is that a behavioral intervention tool adapted for the US military population will be acceptable and associated with a decrease in incident sexually transmitted infection (STI)/HIV rates and high-risk sexual…
- Trial name
- NCT04547413
- Testing
- STI/HIV Intervention Behavioral Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Infection
Emergency Department, Rapid Assessment for Sexually Transmitted Infection
To evaluate if a rapid urine Nucleic Acid Amplification Testing (NAAT) is non-inferior to the traditional swab NAAT for gonorrhea and chlamydia when performed in the Emergency Department.
- Trial name
- ED-RASTI (NCT02386514)
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection
Pharmacy-based Testing and Treatment for Gonorrhea and Chlamydia
Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are the first and second most commonly reported sexually transmitted infections (STI) in Canada, respectively, and rates are increasing.
- Trial name
- NCT06234943
- Testing
- Chlamydia trachomatis and Neisseria gonorrhea self-swab(s) and/or urine collection. Clinical assessment and prescribing of treatment for participants with positive test results
- Where
- 5 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Chlamydia, Gonorrhea
A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities
This study includes testing for four STIs (chlamydia, gonorrhea, syphilis, and HIV) at no cost. If positive, individual subjects will also be counseled and offered options for treatment for themselves and their sex partners that…
- Conditions
- Chlamydia, Gonorrhea, Hiv, Syphilis
- Trial name
- NCT06428643
- Testing
- Chlamydia, gonorrhea, syphilis, and HIV screening
- Where
- United States
- Volunteers
- 2,322 people, healthy volunteers welcome
- Sponsor
- Tulane University
Chlamydia Trachomatis Genital Infection, Gonorrhea
Point of Care Rapid STI Test Optimization and Validation Extension
The purpose of this sub-study (PROVE) is to support and facilitate the validation of commercially available point of care (POC) sexually transmitted infection (STI) diagnostic test kits/devices for potential on-site laboratory…
- Conditions
- Chlamydia Trachomatis Genital Infection, Gonorrhea, Trichomoniasis
- Trial name
- PROVE (NCT06566677)
- Where
- South Africa
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Wits RHI Research Centre Clinical Research Site
Neisseria Gonorrhoeae Infection
SpeeDx Ciprofloxacin gyrA Assay for N. Gonorrhoeae Gonococcal Infection
This study aims to test the effectiveness of using of SpeeDx Resistance Plus assay to guide treatment of Neisseria gonorrhoeae (Ng) in a sexual health clinic setting.
- Trial name
- NCT05286931
- Testing
- Ciprofloxacin 500 mg
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of Washington
Gonorrhea, Sexually Transmitted Infection
Efficacy Trial on Meningococcal B Vaccine for Preventing Gonorrhea Infections
Objectives: Efficacy of a meningococcal vaccine against Neisseria gonorrhoea (NG) infection among men who have sex with men (MSM). Design: Parallel randomised double-blind placebo-controlled trial.
- Trial name
- NCT05766904
- Testing
- 4CMenB vaccine
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Chlamydia Trachomatis, Gonorrhea
Home Screening for Chlamydia Surveillance
This is a randomized controlled trial to determine whether a home screening test for chlamydia and gonorrhea will lead to increased use of screening tests and increased detection of sexually transmitted diseases.
- Trial name
- NCT00177437
- Testing
- home testing kit
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
HIV Infection, Sexually Transmitted Infection
Duo: A Phase IIIb Individual-Level Randomized Controlled Trial of an Integrated Strategy
Individual-Level Randomized Controlled Trial of an Integrated Strategy of HIV pre-exposure prophylaxis (PrEP) and sexually transmitted infection (STI) post-exposure prophylaxis (PEP) for Young Men
- Trial name
- NCT07658976
- Testing
- HIV PrEP - choice of F/TDF, F/TAF, or CAB-LA, STI PEP - Doxycycline as Doxy-PEP, 3P mHealth package
- Where
- 5 sites in United States, Argentina and 2 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Sexually Transmitted Diseases, Syphilis
Doxi-Rio: Study on the Use of Doxycycline to Prevent Sexually Transmitted Infections in Rio de Janeiro
The goal of this clinical trial is to learn if doxycycline post-exposure prophylaxis (doxy-PEP) can help prevent bacterial sexually transmitted infections (STIs) among sexual and gender minorities in Rio de Janeiro, Brazil…
- Conditions
- Sexually Transmitted Diseases, Syphilis, Gonorrhea, Chlamydia Infections
- Trial name
- NCT07500415
- Testing
- Doxycycline
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oswaldo Cruz Foundation
Electrocardiogram Repolarisation Abnormality, Gonococcal Infection
Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects
The Phase I Thorough QT/QTc (TQT) study will be performed in a single center, the Vince \& Associates Clinical Research, Inc., clinical trials unit (CTU), in 72 healthy male or female subjects, aged 18 to 45 years inclusive, to…
- Trial name
- NCT03613649
- Testing
- AZD0914, Moxifloxacin
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Methamphetamine-dependence, Rectal Gonorrhea
Inflammation in Methamphetamine and STIs (IMSTI)
This clinical trial aims to investigate the effects of a decline in methamphetamine use on rectal inflammatory cytokine levels, substance use contexts, and HIV/STI risk behavior.
- Conditions
- Methamphetamine-dependence, Rectal Gonorrhea, Rectal Chlamydia
- Trial name
- IMSTI (NCT05162391)
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gonococcal Infection
Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)
This is a Phase 1, interventional, non-randomized, experimental infection model study in healthy adult males (N=up to 25) between the ages of 18-35 at study enrollment.
- Trial name
- NCT04870138
- Testing
- Azithromycin, Ceftriaxone, Ciprofloxacin
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Neisseria Gonorrhoeae Infection
Study to Assess Gonorrhoeae Immune Responses Induced by a N. Meningitidis Vaccine
The purpose of this study is to test whether the group B meningitis vaccine (brand name Bexsero™) induces immune responses against the bacteria that causes gonorrhea.
- Trial name
- 4CMenB (NCT04094883)
- Testing
- Meningococcal Group B Vaccine
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Gonorrhoea
Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin
This is an open-label Phase I study of plasma, genitourinary, rectal, and pharyngeal pharmacokinetics of a single 1000mg oral dose of solithromycin.
- Trial name
- NCT02348424
- Testing
- Solithromycin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chlamydial Infection, Gonococcal Infection
Clinical Evaluation of the Click Sexual Health Test for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) in Women
This study is a multi-center study with a minimum of three CLIA-waived intended operator sites in the United States in which prospectively self-collected vaginal specimens obtained from subjects who are symptomatic or…
- Conditions
- Chlamydial Infection, Gonococcal Infection, Trichomoniasis
- Trial name
- NCT04098900
- Testing
- Click Sexual Health Test
- Where
- 5 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Visby Medical