Clinical trials: Gonorrhea of Pharynx
Chlamydia Infection, Gonococcal Infection
Use of Abbott RealTime CT/NG to Detect Chlamydia Trachomatis [CT] & Neisseria Gonorrhoeae [NG] in Men Who Have Sex With Men [MSM]
Julius Schachter, PhD, (Department of Laboratory Medicine, University of California, San Francisco) and Susan S. Philip, MD MPH (Department of Medicine, University of California, San Francisco) are conducting a study to evaluate…
- Conditions
- Chlamydia Infection, Gonococcal Infection, Sexually Transmitted Diseases
- Trial name
- NCT01291264
- Where
- 2 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection
Detection of Chlamydia Trachomatis, Neisseria Gonorrhoeae and Mycoplasma Genitalium by Real-time Multiplex Polymerase Chain Reaction (PCR) After Pooling Pharyngeal, Anorectal and Urinary Samples
This study aims to compare the sensitivity of detecting Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium by real-time multiplex PCR in a pooled analysis (i.e.
- Conditions
- Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Mycoplasma Genitalium Infection, Sensitivity
- Trial name
- ISTPOOL (NCT03568695)
- Testing
- Two samples on each of the three sites (pharynx, rectum, urine)
- Where
- 5 sites in France
- Volunteers
- 166 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Gonorrhea
Cefixime Plus Doxycycline Compared to Ceftriaxone Plus Azithromycin for Treatment of Gonorrhoea
A non-inferiority, open-label, multicentre randomised controlled trial to compare two therapeutic regimens for the treatment of uncomplicated urogenital, rectal or pharyngeal gonorrhoea in men and women between 18 and 75 years of…
- Trial name
- NCT06090565
- Testing
- Cefixime, Doxycyclin, Ceftriaxon
- Where
- 2 sites in Czechia
- Volunteers
- 161 people
- Sponsor
- Bulovka Hospital
Gonorrhea, Gonorrhea of Pharynx
BIYELA - Bexsero Immunisation in Young Women in Africa
This proposed 2-arm randomized evaluation of two doses of 4CMenB vaccine versus placebo at Enrollment and Month 2 is designed as a proof-of-concept study to inform potential use for dual meningococcal B and gonococcal prevention…
- Conditions
- Gonorrhea, Gonorrhea of Pharynx, Gonorrhea of Anus, Gonorrhea of Cervix
- Trial name
- NCT06446752
- Testing
- Bexsero
- Where
- 5 sites in South Africa
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection
Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT
The purpose of this study was to use participant samples to simultaneously evaluate three nucleic acid amplification tests (NAATs) diagnostic platforms.
- Conditions
- Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection, Sexually Transmitted Infections
- Trial name
- pNAAT (NCT02870101)
- Testing
- Nucleic acid amplification test 1 for NG and CT, Nucleic acid amplification test 2 for NG and CT, Nucleic acid amplification test 3 for NG and CT
- Where
- 9 sites in United States
- Volunteers
- 2,767 people, healthy volunteers welcome
- Sponsor
- Duke University
Sexually Transmitted Diseases, Chlamydia
Evaluation of NAATs for Detection of C. Trachomatis and N. Gonorrhoeae From Pharynx, Rectum, Glans & Urethra of MSM
Julius Schachter, PhD, from the Department of Laboratory Medicine at UCSF, and Jeffrey Klausner, MD, from the Department of Public Health, are conducting a study to evaluate a type of test (nucleic acid amplification test) for…
- Conditions
- Sexually Transmitted Diseases, Chlamydia, Gonorrhea
- Trial name
- NCT00187902
- Where
- United States
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Neisseria Gonorrhoeae Infection, Asymptomatic Pharyngeal Carriage
Clearance of Asymptomatic Pharyngeal Carriage of Neisseria Gonorrhoeae With or Without Ceftriaxone Treatment: Randomized Non-inferiority Study
Since the use of antibiotics, Neisseria Gonorrhoeae (NG) has acquired progressive resistance to penicillins, sulfonamides, tetracyclines and quinolones.
- Trial name
- PORTAPHAR (NCT05971550)
- Testing
- Absence of antibiotic treatment, Ceftriaxone
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chlamydia Infections, Gonorrhea
Nucleic Acid Amplification Tests (NAATs) for the Diagnosis of Pharyngeal and Rectal Chlamydia and Gonorrhea Infections
Investigators at the University of Alabama in Birmingham in collaboration with investigators from the Centers for Disease Control in Atlanta are evaluating the performance of three commercial nucleic acid amplification tests for…
- Trial name
- NCT00252096
- Testing
- Nucleic acid amplification test
- Where
- United States
- Volunteers
- 3,900 people
- Sponsor
- Centers for Disease Control and Prevention
Gonorrhoea
Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin
This is an open-label Phase I study of plasma, genitourinary, rectal, and pharyngeal pharmacokinetics of a single 1000mg oral dose of solithromycin.
- Trial name
- NCT02348424
- Testing
- Solithromycin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gonorrhea
Antibacterial Mouthwash for Pharyngeal Gonorrhea Prevention
This study aims to determine acceptability and preliminary efficacy of daily use of an antibacterial mouthwash as compared to a placebo mouthwash in reducing the incidence of pharyngeal gonorrhea among a cohort of HIV-positive…
- Trial name
- NCT04966507
- Testing
- Listerine Antiseptic Mouthwash Product, Biotene Mouthwash
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of California, Los Angeles
Gonorrhea of Pharynx, Gonorrhea
Aztreonam for Pharyngeal Gonorrhea
The Centers for Disease Control and Prevention has identified antimicrobial-resistant (AMR) Neisseria gonorrhoeae (NG) as one of the nation's top three urgent AMR threats.
- Trial name
- NCT03867734
- Testing
- Aztreonam
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Washington
Gonorrhea, Neisseria Gonorrhea
Metagenomic Analysis of the Pharynx in High Risk Partners
The Neisseria gonorrhoea (NG) epidemic in England is at the highest level in one hundred years of public health records. The World Health Organisation has listed NG as one of the top five bacterial infections globally because of…
- Conditions
- Gonorrhea, Neisseria Gonorrhea, Neisseria Meningitidis, Metagenomic Next Generation Sequencing
- Trial name
- NCT07671014
- Volunteers
- 100 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pharyngeal Gonococcal Infection
Gent for Pharyngeal Gonorrhea (GC)
The Centers for Disease Control and Prevention has identified antimicrobial-resistant (AMR) Neisseria gonorrhoeae (NG) as one of the nation's top three urgent AMR threats.
- Trial name
- NCT03632109
- Testing
- gentamicin 360mg IM
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Washington
Neisseria Gonorrhoeae (Ng) Infections
Efficacy of Temocillin Compared to Standard of Care in the Treatment of Neisseria Gonorrhoeae Infections
Neisseria gonorrhoeae (Ng) infections are common and increasing in incidence. Treatment with a third generation cephalosporin, i.e ceftriaxone 1g, single dose, intramuscular (IM), is recommended as a first line treatment.
- Trial name
- TEMtoGo (NCT07631364)
- Testing
- Temocillin (NEGABAN®) 2 g intravenous with lidocaine (3ml), Rectal swab for ESBL-E and microbiota (Eswab), Temocillin (NEGABAN®) 2 g intramuscular single dose with lidocaine (3ml)
- Where
- France
- Volunteers
- 360 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris