Clinical trials: Graft Function
Diastolic Dysfunction, Coronary Artery Disease
Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index
The purpose of this study is to determine the effect of inhaled anesthetic drugs upon diastolic heart function (heart suction and filling performance) in patients who are undergoing coronary bypass surgery.
- Conditions
- Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia
- Trial name
- NCT00907439
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
Stem Cell Transplantation, Hematopoietic, Poor Graft Function
Peripheral Blood Stem Cell Combined With Mesenchymal Stem Cells for Treatment of Poor Graft Function
The purpose of this study is to evaluate the utility of treating patients experiencing poor graft function after allogeneic hematopoietic stem cell transplantation with Granulocyte Colony-Stimulating Factor (G-CSF) mobilized…
- Conditions
- Stem Cell Transplantation, Hematopoietic, Poor Graft Function, Hematological Diseases
- Trial name
- NCT02083718
- Testing
- PBSC, MSCs
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Dental Implant, Bone Grafting
Influence of Alveolar Bone Drilling and Anatomical Position on Integration
The goal of this clinical trial is to learn if alveolar bone drilling and anatomical position of an immediately placed dental implant has influence on the primary stability, osseointegration and function.
- Conditions
- Dental Implant, Bone Grafting, Immediate Dental Implant Placement
- Trial name
- NCT07589140
- Testing
- dental implant placement, Dental implant
- Where
- Lithuania
- Volunteers
- 124 people
- Sponsor
- Lithuanian University of Health Sciences
Breast Neoplasms, Carcinoma, Ductal, Breast
Study of Autologous Fat Enhanced w/ Regenerative Cells Transplanted to Reconstruct Breast Deformities After Lumpectomy
A post-marketing study evaluating the transplantation of autologous fat augmented with Adipose Derived Regenerative Cells (ADRCs), in patients with functional and cosmetic breast deformities post segmental mastectomy or…
- Conditions
- Breast Neoplasms, Carcinoma, Ductal, Breast, Mammaplasty, Mastectomy, Segmental, Lumpectomy, Breast Reconstruction,
- Trial name
- RESTORE-2 (NCT00616135)
- Testing
- ADRC-Enhanced Autologous Fat Transplant
- Where
- 5 sites in Belgium, Italy and 2 more
- Volunteers
- 71 people
- Sponsor
- Cytori Therapeutics
Kidney Transplantation, Delayed Graft Function
Evaluation of CAF22 After Renal Transplantation
Established markers of kidney function, such as creatinine, have considerable limitations in the diagnosis of delayed graft function (DGF) after kidney transplantation (KT).
- Trial name
- NCT02346968
- Testing
- Blood and urine sampling
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 99 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Vasodilation
Effects of Exercise Training on Vascular Endothelial Function of Patients Submitted to Coronary Artery Bypass Graft
Objective: To observe the effects of exercise training on vascular endothelial function in patients undergoing coronary artery bypass graft (CABG) alone in phase III after six months of Cardiac rehabilitation programs (CRP).
- Trial name
- NCT02265107
- Testing
- exercise training
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- Universidade Federal do Rio Grande (FURG)
Ischemic Heart Disease, Bone Marrow Cells
Autologous Bone Marrow Mononuclear Cells in the Combined Treatment of Coronary Heart Disease
The purpose of this study evaluate the effect of the method of administration of autologous bone marrow mononuclear cells for the duration of of functioning aorto-coronary bypass grafts in the surgical treatment of coronary heart…
- Conditions
- Ischemic Heart Disease, Bone Marrow Cells, Coronary Artery Bypass Grafting (CABG), Heart Failure, Diastolic
- Trial name
- TAMIS (NCT02059512)
- Testing
- Group 1, Group 0, Group 2
- Where
- Russia
- Volunteers
- 117 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Delayed Graft Function
Reduce the Severity of DGF in Recipients of a Deceased Donor Kidney
The major objective is to demonstrate the safety and efficacy of ANG-3777 in improving graft function and reducing the severity of delayed graft function (DGF) in recipients at high risk of DGF after receiving a deceased donor…
- Trial name
- NCT02474667
- Testing
- ANG-3777
- Where
- 30 sites in United States
- Volunteers
- 253 people
- Sponsor
- Angion Biomedica Corp
Kidney Transplantation, Vitamin D Deficiency
Vitamin D3 Substitution in Vitamin D Deficient Kidney Transplant Recipients
The purpose of the study is to evaluate the effects of Cholecalciferol (Vitamin D3) substitution on the posttransplant outcome (glomerular filtration rate as well as serum creatinine levels, number of acute rejection episodes…
- Conditions
- Kidney Transplantation, Vitamin D Deficiency, Renal Osteodystrophy
- Trial name
- VITA-D (NCT00752401)
- Testing
- Cholecalciferol
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna
Coronary Artery Disease, CABG
Clinimetric Properties of Performance Based Functional Outcome Measure After (CABG) Surgery
The purpose of this research is to determine which performance based functional outcome test among Time up and go test, Five times sit to stand test, 2 minute walk test and 6 minute walk test has the greatest significance in…
- Trial name
- NCT07060937
- Testing
- Physiotherapy Protocol
- Where
- 2 sites in Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Renal Transplant Surgery
Goal Directed Hemodynamic Management and Renal Outcome After Renal Transplant Surgery
This study is designed to compare the incidence of delayed graft function in patients following renal transplant surgery with different perioperative hemodynamic managements: a goal directed hemodynamic management group (using…
- Trial name
- IROR (NCT01485432)
- Testing
- PiCCO® Monitoring
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Technical University of Munich
Disorder Related to Renal Transplantation
Curcumin in Kidney Transplant Recipients
The primary goal of this study is to investigate if curcumin is beneficial for kidney transplant recipients, a population with extensive baseline vascular dysfunction and cognitive impairment who have few treatment options.
- Trial name
- NCT03935958
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Illinois Chicago
Delayed Graft Function
Delayed Renal Allograft Function and Furosemide Treatment
This study will be a randomized prospective double-blind placebo-controlled clinical pilot trial. This will be a single center project that will take place at Loma Linda University Medical Center.
- Trial name
- DRAFFT (NCT02312115)
- Testing
- Furosemide
- Where
- United States
- Sponsor
- Loma Linda University
Kidney Transplant; Complications, Kidney Transplant Failure
Can Dapagliflozin Preserve Structure and Function in Transplanted Kidneys?
The goal of this clinical trial is to look at the effect of SGLT2 (Sodium glucose transporter 2) inhibition in patients receiving a kidney-transplant 6 weeks earlier at Oslo University hospital. Rikshospitalet.
- Conditions
- Kidney Transplant; Complications, Kidney Transplant Failure, Renal Failure
- Trial name
- DEAKTransplant (NCT05788276)
- Testing
- Dapagliflozin 10mg Tab
- Where
- Norway
- Volunteers
- 330 people
- Sponsor
- Oslo University Hospital
Bronchiolitis Obliterans Syndrome
Novel Pulmonary Function Measures for Diagnosis of Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem-Cell Transplantation in Children
In this study, we will study 129Xe-MRI and LCI as tools for diagnosis of BOS in pediatric patients who have received Hematopoietic Stem Cell Transplantation (HSCT) and have been identified as eligible for this study.
- Trial name
- NCT04391335
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- The Hospital for Sick Children
Coronary Artery Bypass Graft Surgery Patients
Improving Outcomes and Quality of Life After CABG
The principal objective to this randomized trial is to compare the efficacy of two strategies of intra-operative hemodynamic management during cardiopulmonary bypass among patients undergoing primary elective coronary artery…
- Trial name
- NCT00256620
- Testing
- Mean arterial pressure during cardiopulmonary bypass 80 mmHg vs. customized
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Weill Medical College of Cornell University
Leukaemia (Chronic)
What is the Impact of TKI on Thyroid Function in CML Patients?
Evaluation of the impact of various TKI on thyroid function in patients diagnosed with cml
- Trial name
- NCT07200882
- Volunteers
- 76 people
- Sponsor
- Assiut University
Lumbar Radiculopathy
Effects of Decompression in Patient With Acute vs Chronic Lumbar Radiculopathy
The study will be done to evaluate the effectiveness of Lumbar Spinal Decompression in patients with acute vs chronic lumbar radiculopathy. Study design will be Randomized control trial and sample size will be 30.
- Trial name
- NCT04674917
- Testing
- Decompression + Hot pack, TENS, Mobilization, Exercise Therapy, Decompression + Hot pack , TENS , Mobilization , Exercise Therapy, Hot pack , TENS, Mobilization, Exercise therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Kidney Transplant, Kidney Failure
Preventing Delayed Graft Function in Kidney Transplant Patients
The health and quality of life benefits of kidney transplantation are reduced by delayed graft function (DGF). There are a number of modifiable risk factors associated with DGF, such as intraoperative hypotension, the type of…
- Conditions
- Kidney Transplant, Kidney Failure, Kidney Injury
- Trial name
- PDF (NCT06724211)
- Testing
- Treatment bundle of care, Control Group
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Deceased Organ Donor, Mild Hypothermia
The Effect of Therapeutic Hypothermia on Deceased Donor Renal Graft Outcomes - a Randomized Controlled Trial From the Region 5 Donor Management Goals Workgroup
To protect kidney function during the transplantation process by inducing mild hypothermia in the deceased organ donor before organs are recovered
- Conditions
- Deceased Organ Donor, Mild Hypothermia, Renal Function
- Trial name
- NCT01680744
- Testing
- Hypothermia
- Where
- United States
- Volunteers
- 370 people
- Sponsor
- University of California, San Francisco