Clinical trials: Graft Occlusion, Vascular
Prevention & Control
Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease
The primary objectives of this study are: To determine whether rivaroxaban 2.5 mg twice daily (bid) + aspirin 100 mg once daily (od) compared with aspirin 100 mg od reduces the risk of a composite of myocardial infarction…
- Trial name
- COMPASS (NCT01776424)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Aspirin, Pantoprazole
- Where
- 565 sites in United States, Argentina and 31 more
- Volunteers
- 27,395 people
- Sponsor
- Bayer
Coronary Artery Disease
The Effect of Resistance Training on Proprotein Subtilisin Convertase Kexin 9 Level After Coronary Bypass Surgery
This research add resistance training to patients who undergo cardiac rehabilitation program after coronary bypass surgery, comparing the level of PCSK9 level on that group to another group who receives conventional…
- Trial name
- NCT02674659
- Testing
- resistance training, aerobic training
- Volunteers
- 87 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Percutaneous Coronary Intervention, Coronary Artery Bypass Graft Surgery, With or Without Valve Surgery
Cardiac Rehabilitation Peer Mentorship
The current study is a randomized controlled trial, being conducted at two hospitals in Toronto, Ontario, Canada, involving the randomization of cardiac inpatients into an intervention group, in which they will receive mentorship…
- Conditions
- Percutaneous Coronary Intervention, Coronary Artery Bypass Graft Surgery, With or Without Valve Surgery, Acute Coronary Syndrome, Chronic Stable Heart Failure
- Trial name
- NCT02204449
- Testing
- Cardiac Rehabilitation Peer Mentorship
- Where
- 2 sites in Canada
- Volunteers
- 94 people
- Sponsor
- University Health Network, Toronto
Peripheral Arterial Occlusive Disease (PAOD)
Evaluation of FUSION™ Vascular Graft for Above Knee Targets
The purpose of the post-market study was to evaluate the safety and performance of the FUSION Vascular Graft.
- Trial name
- PERFECTION (NCT01601496)
- Testing
- FUSION Vascular Graft
- Where
- 10 sites in Austria, Germany
- Volunteers
- 117 people
- Sponsor
- Maquet Cardiovascular
Thoracic Aortic Aneurysms, and Penetrating Atherosclerotic Ulcers
Phase II Study of the Safety and Efficacy of the Relay Thoracic Stent-Graft
The purpose of this study is to evaluate the safety and efficacy of the Relay thoracic stent-graft system to treat thoracic aortic aneurysms.
- Trial name
- NCT00435942
- Testing
- Relay Thoracic Stent-Graft, Open Repair
- Where
- 27 sites in United States
- Volunteers
- 180 people
- Sponsor
- Bolton Medical
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
Transitional Rehabilitation in CABG Patients
The goal of this research study is to understand whether an at-home exercise program started soon after CABG surgery, and continuing for 4 weeks following discharge from the hospital, can preserve or improve physical function.
- Trial name
- NCT03892460
- Testing
- neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Vermont
Heart Diseases, Coronary Artery Disease
Intraoperative Echocardiography in Low-Risk CABG Surgery
This goal of this study is to better understand when and where intraoperative transesophageal echocardiography (TEE) should (or should not) be used during coronary artery bypass graft (CABG) surgeries.
- Conditions
- Heart Diseases, Coronary Artery Disease, Chest Pain, Stenosis Coronary
- Trial name
- NCT06154265
- Testing
- TEE probe
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Peripheral Arterial Occlusive Disease
Study Comparing Synthetic Vascular Grafts in Patients With Peripheral Artery Disease (PAD) Who Require Artery Bypass.
To demonstrate the patency and safety of vascular grafts: EXXCEL and FUSION Bioline.
- Trial name
- FINEST (NCT01113892)
- Testing
- vascular grafts
- Where
- 25 sites in United States, Czechia and 1 more
- Volunteers
- 207 people
- Sponsor
- Maquet Cardiovascular
Peripheral Arterial Disease
Endothelial Function in Lower Extremity Bypass Grafts
This study will determine whether or not saphenous vein [arterial] bypass grafts in the leg relax in response to increases in blood flow.
- Trial name
- NCT00759707
- Testing
- L-N^G monomethyl arginine (L-NMMA)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Brigham and Women's Hospital
Peripheral Arterial Occlusive Disease
GORE PROPATEN Vascular Graft vs. Disadvantaged Autologous Vein Graft
The primary patency of the GORE PROPATEN Vascular Graft is equivalent to or better than disadvantaged autologous vein graft in an infragenicular peripheral bypass application at 12 months.
- Trial name
- PRODIGY (NCT00617279)
- Testing
- GORE PROPATEN Vascular Graft, Disadvantaged Autologous Vein Graft
- Where
- 17 sites in United States
- Volunteers
- 31 people
- Sponsor
- W.L.Gore & Associates
Peripheral Arterial Disease
A Study of the Gore VIABAHN BX for Treatment of Occlusive Disease in the Iliac Arteries.
Evaluation of the Gore(R) VIABAHN BX for the treatment of arterial occlusive disease in the common and/or external iliac arteries.
- Trial name
- VBXFLEX (NCT02080871)
- Testing
- Stenting of the Common and/or External Iliac Arteries
- Where
- 27 sites in United States, New Zealand
- Volunteers
- 134 people
- Sponsor
- W.L.Gore & Associates
Coronary Artery Disease
Transepicardial With Transseptal Autologous CD 133+ Bone Marrow Cell Implantation in Patient Following CABG Surgery
Heart Failure has several etiologies and one of them is coronary artery disease. Coronary artery bypass grafting (CABG) is one of revascularizations method which has been used for decades in coronary artery disease theraphy.
- Trial name
- NCT02870933
- Testing
- Transepicardial with Transseptal CD 133+ Implantation
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Peripheral Arterial Disease
Belgian Trial Investigating the LifeStream Stent in Complex TASC C and D Iliac Lesions
The BELSTREAM Trial investigates the efficacy of the LifeStream Peripheral Stent Graft System in the treatment of iliac stenotic or occlusive lesions (TASC C and D). An expected total of 70 patients will be treated.
- Trial name
- BELSTREAM (NCT03349996)
- Testing
- LifeStream Peripheral Stent Graft System
- Where
- 7 sites in Belgium
- Volunteers
- 70 people
- Sponsor
- ID3 Medical
Peripheral Arterial Disease
The PQ Bypass Pivotal IDE Intra-arterial Stent Graft Study
The primary objective of the TORUS 2 IDE Clinical Study is to evaluate the safety and effectiveness of the TORUS Stent Graft System in the treatment of obstructive atherosclerotic lesions of the native SFA or the superficial…
- Trial name
- TORUS2 (NCT04130737)
- Testing
- TORUS Stent Graft System
- Where
- 32 sites in United States
- Volunteers
- 188 people
- Sponsor
- Endologix
Venous Stenosis, Venous Occlusion
The Merit WRAPSODY AV Access Efficacy Study (WAVE)
The purpose of the study is to demonstrate the safety and efficacy of the Merit WRAPSODY Endovascular Stent Graft for treatment of stenosis or occlusion within the dialysis access outflow circuit
- Trial name
- WAVE (NCT04540302)
- Testing
- Merit WRAPSODY Endovascular Stent Graft, PTA
- Where
- 43 sites in United States, Brazil and 2 more
- Volunteers
- 357 people
- Sponsor
- Merit Medical Systems, Inc.
Of Bypass Graft of the Extremities, Peripheral Arterial Disease
Standard Versus PICO Dressings in Lower-Extremity Bypass Patients
The objective of this study is to compare the effectiveness of standard moist dressings and PICO single-use negative pressure dressings in post-operative lower extremity bypass patients.
- Conditions
- Of Bypass Graft of the Extremities, Peripheral Arterial Disease, Vascular Diseases, Cardiovascular Diseases
- Trial name
- PICO-LEB (NCT02492854)
- Testing
- PICO Single-Use Negative Pressure Dressings, Sterile Gauze Dressings
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston Medical Center
Aortic Aneurysm, Penetrating Ulcer
TX2® Low Profile TAA Endovascular Graft
The Zenith® TX2® Low Profile TAA Endovascular Graft study is a clinical trial approved by US FDA to evaluate the safety and effectiveness of the Zenith® TX2® Low Profile TAA Endovascular Graft indicated for the treatment of…
- Conditions
- Aortic Aneurysm, Penetrating Ulcer, Vascular Disease
- Trial name
- TX2® LP (NCT01151020)
- Testing
- Zenith® TX2® Low Profile TAA Endovascular Graft
- Where
- 33 sites in United States, Germany and 4 more
- Volunteers
- 110 people
- Sponsor
- Cook Research Incorporated
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Coronary Artery Disease, Edema
The Efficacy and Safety of Hypertonic Saline in Cardiac Surgery Patients.
The organ dysfunction following cardiopulmonary bypass (CPB) occurs frequently in cardiac surgery patients. Systemic inflammatory response initiated by CPB through releasing of several mediators lead to altered endothelial…
- Trial name
- ESHHS (NCT01675453)
- Testing
- 7.2% NaCl plus 6% hydroxyethyl starch 200/0.5, 0.9% NaCl
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease
Effect of an Educational Intervention on Cardiac Patients' Participation Rate in Cardiac Rehabilitation Programs
The main aim of the study is to determine the effectiveness of an educational intervention designed to increase attendance of coronary artery bypass grafting (CABG) patients at Cardiac Rehabilitation Programs (CRPs) on actual CRP…
- Trial name
- MECRIS (NCT00356863)
- Testing
- Increasing awareness to cardiac rehabilitation programs
- Where
- Israel
- Volunteers
- 1,024 people
- Sponsor
- Sheba Medical Center