Clinical trials: Grave's Disease
Multinodular Goitre, Grave's Disease
A Prospective Randomized Equivalence Trial to Evaluate the Safety of the Ligasure in Thyroid Surgery
This is a randomized, prospective equivalence trial on the safety of the Ligasure Vessel Sealing System as used in thyroid surgery.
- Conditions
- Multinodular Goitre, Grave's Disease, Thyroid Nodule
- Trial name
- NCT01163565
- Testing
- Ligasure Device
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of Alberta
Thyroid Associated Ophthalmopathy
Orbital Radiotherapy in Grave's Ophthalmopathy 1 Week vs 2 Weeks (OraGO-1 Trial)
Thyroid ophthalmopathy, also known as thyroid eye disease or Graves' ophthalmopathy, is a condition characterized by inflammation and swelling of the tissues around the eyes, often accompanied by protrusion of the eyeballs.
- Trial name
- NCT06392906
- Testing
- Short course radiation therapy, Standard course radiation therapy
- Where
- Thailand
- Volunteers
- 68 people
- Sponsor
- Janjira Petsuksiri
Graves Disease
Evaluation of Optimal Time of Methimazole Discontinuation Before Radio-iodine Therapy in Hyperthyroid Grave's Patients
Iodine therapy is the best treatment for graves disease.Most patients receive methimozale prior to radio-iodine treatment. This may decrease treatment response to iodine therapy.
- Trial name
- NCT01560299
- Testing
- Methimazole
- Where
- Iran
- Volunteers
- 150 people
- Sponsor
- Mashhad University of Medical Sciences
Autoimmune Thyroid Disease
The Prevalence of Serum Thyroid Hormone Autoantibodies in Autoimmune Thyroid Diseases
Thyroid hormone autoantibodies(THAA) in serum can Interfere radioimmunoassay for the determination of free thyroid hormones. Thyroid function test plays a key role in the diagnosis and treatment of autoimmune thyroid disease…
- Trial name
- NCT04075851
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Hyperthyroidism, Hypothyroidism
Natural History of Thyroid Function Disorders
Participants in this study will be patients diagnosed with or suspected to have a thyroid function disorder. These conditions may include: hypothyroidism, hyperthyroidism, thyroid hormone resistance, Graves' Dermopathy, and…
- Conditions
- Hyperthyroidism, Hypothyroidism, Grave's Disease
- Trial name
- NCT00001159
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Strabismus, Mechanical, Graves Ophthalmopathy
Supramaximal Rectus Recession for Strabismus in Grave's Ophthalmopathy
The purpose of this study is to evaluate supramaximal rectus recession for strabismus in Grave's Ophthalmopathy
- Trial name
- NCT04927468
- Testing
- supramaximal rectus recession, normal rectus recession
- Volunteers
- 60 people
- Sponsor
- Sun Yat-sen University
Graves Ophthalmopathy
Comparison Study Between Two Techniques for Correction of Upper Lid Retraction in Patients With Grave's Orbitopathy
Grave's ophthalmopathy is the most common cause of orbital disease in adults. The clinical presentation may vary between sub clinic symptoms to severe ones.
- Trial name
- NCT01999790
- Testing
- blepharotomy, posterior approach
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Graves' Disease, Graves' Ophthalmopathy
Color Doppler Imaging of Orbital Venous Flow in Grave's Orbitopathy
Orbital Venous flow study in patients with Grave's Orbitopathy in different manifestation forms and stages, made with Color Doppler Imaging
- Trial name
- NCT00697528
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hyperthyroidism, Tomography
Comparison of SUV Using SPECT/CT Between Grave's Disease Patients and Normal Humans
The purpose of this study is to find out the capacity of standardized uptake value (SUV) using single-photo emission computed tomography and computed tomography (SPECT/CT) in diagnosing Grave's Disease (hyperthyroidism).
- Conditions
- Hyperthyroidism, Tomography, Emission-Computed, Single-Photon
- Trial name
- NCT02772705
- Where
- 9 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Graves' Disease
Comparative Study of Different I-131 Doses in Graves' Disease
Radioactive iodine (RAI) administration is an effective and completely established treatment modality in hyperthyroidism including Graves' disease.
- Trial name
- NCT02114619
- Testing
- Low dose of I-131, Intermediate dose, High dose
- Where
- Iran
- Volunteers
- 450 people
- Sponsor
- Mashhad University of Medical Sciences
Graves Ophthalmopathy, Surgery
Modified Orbital Decompression in the Treatment of Moderate-to-severe Grave's Ophthalmopathy
To investigate the efficacy and safety of modified deep lateral wall decompression and/or medial wall decompression for Moderate-to-severe Grave's Ophthalmopathy.
- Trial name
- NCT06588764
- Testing
- modified deep lateral and/or medial wall decompression
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Graves' Disease, Thyroid Disease
Shared Decision Making in Graves Disease - Graves Disease (GD) Choice
The investigators' decision aid for patients with GD, GD Choice, will be the result of a user-centered participatory action research involving) synthesis of the best available evidence from the literature and real-world registry…
- Conditions
- Graves' Disease, Thyroid Disease, Hyperthyroidism
- Trial name
- NCT02107794
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Mayo Clinic
Graves Disease
The Impact of Person Centred Care (PCC) in Grave's Disease
Mental fatigue (MF) is prevalent after Graves' disease (GD), which is the most common form of hyperthyroidism. We have reported that 38% of patients, compared to 11% of control subjects, suffer from MF more than 1 year after…
- Trial name
- NCT06309316
- Testing
- Person-centred care (PCC)
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Vastra Gotaland Region
Graves Disease
Effects of Vitamin D Supplementation on Muscle Function Among Grave's Disease Patients
Introduction: A deficit in vitamin D may be involved in the development and presentation of Graves' disease (GD). Lack of vitamin D and GD are linked to deteriorating quality of life (QoL) and weakening of the muscles.
- Trial name
- NCT06451016
- Testing
- Vitamin D supplements
- Where
- 2 sites in Pakistan
- Volunteers
- 48 people
- Sponsor
- Frontier Medical and Dental College, Abbotabad