Clinical trials: Ground-Glass Opacity, open to volunteers
Lung Ground-Glass Opacity
GGO-dominant PPLs Diagnosis Using CLE and ssRAB-guided Cryobiopsy
The purpose of the study is to evaluate the diagnostic performance and safety of cryobiopsy for ground-glass opacity (GGO)-dominant peripheral pulmonary lesions (PPLs) under the guidance of shape-sensing robotic-assisted…
- Trial name
- NCT06910046
- Testing
- CLE and ssRAB-guided cryobiopsy
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Shanghai Chest Hospital
Lung Ground-glass Opacities, Active Surveillance
Active Surveillance for Limited GGNs
This study is a single-arm, multi-center, phase III trial conducted under the Eastern Cooperative Thoracic Oncoloy Project (ECTOP) .
- Trial name
- NCT06394037
- Testing
- Active surveillance
- Where
- China
- Volunteers
- 387 people
- Sponsor
- Fudan University
Pulmonary Nodules, Lung Neoplasms
Deep Learning Time-Series Prediction of Long-Term Growth Patterns of Pulmonary Ground-Glass Nodules Using Serial CT
Pulmonary ground-glass nodules (GGNs) are commonly found on chest CT scans. Some stay stable for years, while others slowly or rapidly turn into lung cancer.
- Conditions
- Pulmonary Nodules, Lung Neoplasms, Adenocarcinoma of Lung
- Trial name
- GGN-Trajectory (NCT07647692)
- Testing
- Serial Thin-Slice Chest CT
- Where
- China
- Volunteers
- 4,750 people
- Sponsor
- Peking University People's Hospital
Lung Cancer
Osimertinib to Suppress the Progression of GGN(EGFR Mutation-positive)
This study designed to assess the efficacy of osimertinib (80 mg, orally, once daily) to suppress the progression of remaining GGN(s) in other lobes following surgical resection for actionable EGFR mutation-positive stage I lung…
- Trial name
- NCT04591002
- Testing
- Osimertinib 80 MG
- Where
- 2 sites in South Korea
- Volunteers
- 43 people
- Sponsor
- Samsung Medical Center
Lung Cancer, Wedge Resection
Wedge Resection for Ground-glass Opacity-featured Lung Cancer (ECTOP-1020)
This is a clinical trial from the Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1020. The goal of this clinical trial is to confirm the therapeutic effect of Wedge resection for ground-glass…
- Conditions
- Lung Cancer, Wedge Resection, Ground-glass Opacity
- Trial name
- NCT06102161
- Testing
- Wedge resection
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Fudan University
Ground-Glass Opacity
Cryoablation vs Thoracoscopic Surgery for GGN
The aim of this study is to investigate the efficacy and safety of Cryoablation and Thoracoscopic Surgery in the treatment of pulmonary ground-glass nodules.
- Trial name
- NCT06848881
- Testing
- Cryoablation, Thoracoscopic Surgery
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Chest Hospital
Lung Adenocarcinoma
Osimertinib to Suppress the Progression of Remaining GGN for EGFR Mutation-positive Stage IB-IIIA Lung Adenocarcinoma
This is an open label, phase II study to assess the efficacy of osimertinib (80 mg, orally, once daily) to suppress the progression of remaining GGN(s) in other lobes following surgical resection for actionable EGFR…
- Trial name
- NCT05528458
- Testing
- Osimertinib 80Mg Tab
- Where
- South Korea
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Pulmonary Nodules, Ground-glass Opacity
Percutaneous Robotic Navigation Microwave Ablation Versus CT-guided Microwave Ablation in the Treatment of Pulmonary Nodules With Ground-glass Opacity
1. To compare the precision of robot-guided microwave ablation and CT-guided microwave ablation in the treatment of ground-glass nodules. 2.
- Trial name
- NCT07389889
- Testing
- Robot, CT scan
- Volunteers
- 116 people
- Sponsor
- Fujian Medical University Union Hospital
Lung Ground-glass Opacities, Active Surveillance
Surveillance for Multifocal GGNs
This study is a single-arm, multi-center, phase III trial conducted under the Eastern Cooperative Thoracic Oncoloy Project (ECTOP) with the identification number ECTOP-1021.
- Trial name
- NCT06097910
- Testing
- Watchful waiting
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Fudan University