Clinical trials: Growth Disorders
Chronic Periodontitis
To Study the Healing Effect of 0.25% Lemongrass Oil Mouthwash on Chronic Periodontitis Patients.
Periodontitis is the inflammation of the tissues supporting the teeth. Lemongrass (Cymbopogon Citratus) oil mouthwash can be used with subgingival scaling in the treatment of periodontal diseases.
- Trial name
- NCT05502627
- Testing
- 0.25% lemon grass oil mouthwash
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Medical Institute, Lahore
Stunting
Effectiveness of SNF, Cash and BCC to Prevent Stunting Among Children 6-24 Months in Rahim Yar Khan, Pakistan
Malnutrition is a public health problem, with long-lasting physiological consequences and increased risk of morbidity and mortality.
- Trial name
- NCT03299218
- Testing
- SNF (Wawamum), Social and behaviour change communication (SBCC), Cash
- Where
- Pakistan
- Volunteers
- 2,179 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Gestational Diabetes, High Blood Pressure
Social Deprivation and Pregnancy
Social deprivation during pregnancy is associated to adverse perinatal outcomes. However, prenatal screening of social deprivation by reliable measurement is not performed.
- Conditions
- Gestational Diabetes, High Blood Pressure, Prematurity, Fetal Growth Restriction
- Trial name
- NCT03121196
- Testing
- Epices score
- Where
- France
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Fetal Growth Retardation
Arginine + Citrulline as a Supplement for Weight Gain in Fetus With a Decrease in Their Growth Curve
Introduction: The high incidence of intrauterine growth restriction is a public health problem; in this pathology, newborns present weight below the 10th percentile, this implies an increase in morbidity in the short term…
- Trial name
- NCT05029778
- Testing
- L-arginine 3g + L-Citruline 2 g
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hospital Civil de Guadalajara
Body Weight, Obesity & Overweight
Breastmilk and the Link to Overweight/Obesity and Maternal Diet in the Mother-breastmilk-child Triad
The prospective 5-month follow-up study will involve 150 mother-infant dyads grouped based on maternal baseline BMI category (normal weight, overweight, obesity).
- Conditions
- Body Weight, Obesity & Overweight, Human Milk/Breastfeeding, Body Composition
- Trial name
- BLOOM-Triad (NCT07457515)
- Where
- 4 sites in Canada, Poland
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Warsaw University of Life Sciences
Zika, Neurodevelopmental Abnormality
International Cohort Study of Children Born to Women Infected With Zika Virus During Pregnancy
The International Cohort Study of Children Born to Women Infected with Zika Virus (ZIKV) During Pregnancy study is a prospective, observational, international cohort study of children previously enrolled in the ZIP study or other…
- Conditions
- Zika, Neurodevelopmental Abnormality, Hearing Loss, Growth Delay
- Trial name
- NCT04118738
- Where
- 5 sites in Brazil, Colombia and 2 more
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Westat
Irritable Bowel Syndrome
A Phase 1, First Time in Human (FTIH) Study to Evaluate GSK3352589, a REarranged During Transfection (RET) Growth Factor Receptor Tyrosine Kinase Inhibitor, in Healthy Volunteers
This FTIH study is designed to assess the safety, tolerability and pharmacokinetic (PK) of escalating single and repeat oral doses of GSK3352589 in normal healthy volunteers.
- Trial name
- NCT03154086
- Testing
- GSK3352589
- Where
- Australia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Bronchopulmonary Dysplasia
MRI in BPD Subjects
The investigators are wanting to learn more about early development of the lungs and to help them better understand prematurity and the development of a breathing disorder call BPD (Bronchopulmonary Dysplasia)
- Trial name
- NCT03657693
- Testing
- NICU MRI, Polysomnography
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Sleep Apnea, Pregnancy
Pregnancy, Sleep Disordered Breathing and Peripartum Complications
Sleep disordered breathing (SDB) during pregnancy is a modifiable risk factor for poor maternal and fetal outcomes. The investigators propose a prospective observational study to assess the utility of continuous positive airway…
- Trial name
- NCT02651649
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Alzheimer's Disease, Mild Cognitive Impairment
System-IGF-1 Pathway and Alzheimer's Disease
The aim is to assess the relationship between levels of IGF-I system components and cognitive status in patients with Alzheimer's disease (AD), in elderly subjects with normal cognitive function, and in patients with mild…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Cognitive Function 1, Social, Control With Normal Activities of Daily Living
- Trial name
- SIGAL (NCT00647478)
- Where
- France
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preeclampsia
Gene Expression In Pregnancies Complicated by Preeclampsia
The purpose of this study is to figure out some of the differences in bodily function between women who have preeclampsia and those who do not. This may eventually lead to an understanding of its cause.
- Trial name
- NCT00919360
- Testing
- collection of maternal blood specimen prior to delivery, collection of placental cord blood after delivery, collection of placental tissue
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Concentrated Growth Factors, Periodontal Regeneration
Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans
Objective: To compare the effect of guided tissue regeneration (GTR) + concentrated growth factors (CGF) + bone graft and CGF + bone graft in the treat of II° furcations of human mandibular molars.
- Conditions
- Concentrated Growth Factors, Periodontal Regeneration, Furcation Defects
- Trial name
- NCT03180658
- Testing
- GTR + CGF + bone graft, CGF + bone graft
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jing Qiao
Stunting
Gut Microbiota Stunted Children NTT
NTT Province is on the list of priority areas of high prevalence of stunting, Southwest Sumba, South Middle East, and Kupang district have a stunting prevalence of 36.2%, 34.5% and 48.1% respectively in 2020.
- Trial name
- NCT05119218
- Testing
- No Intervention
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bina Nusantara University
Stunting, Environmental Enteric Dysfunction
The Effect of Bovine Colostrum/ Egg Supplementation in Young Malawian Children
The trial will consist of adding either a supplement of 4.3g egg powder + 5.7g bovine colostrum or a control flour along with a multiple micronutrient powder to the diets of healthy Malawian children 9 months of age.
- Trial name
- NCT03801317
- Testing
- BC/ egg, Control, multiple micronutrient
- Where
- Malawi
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Osteopenia
Study of Growth Hormone and Bone in Obesity
Obesity is an important risk factor for osteoporosis and fractures. With the growing prevalence of obesity in the U.S., understanding the pathophysiology of bone loss in this population is of importance to public health.
- Trial name
- NCT01724489
- Testing
- Growth hormone
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Premature Birth
Feeding and Transition to Home for Preterms at Social Risk
Premature infants are at high risk of suboptimal health and development. This randomized clinical trial evaluated the impact of a developmentally based intervention, H-HOPE (Hospital-home transition: optimizing prematures'…
- Trial name
- H-HOPE (NCT02041923)
- Testing
- H-HOPE, Attention Control
- Where
- 2 sites in United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Growth Failure, Adiposity
Optimal Growth of Preterm Infants With Growth Restriction
In this prospective randomized controlled multi center trial the investigators stratify "Very Low Birthweight " (VLBW)-infants with growth retardation in small for gestational age (SGA) or intrauterine growth restricted (IUGR) …
- Conditions
- Growth Failure, Adiposity, Diabetes, Neurologic Deficits
- Trial name
- OPTIGROW (NCT02999945)
- Testing
- SGA-enhanced nutrients, IUGR-enhanced nutrients, SGA-standard nutrients
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Periodontal Disease
Endocan, VEGF and TNF-alpha Levels in Periodontal Disease and After Treatment
The primer aim of the study was to determine serum and gingival crevicular fluid (GCF) endocan levels in periodontal diseases pathogenesis supported with vascular endothelial growth factor (VEGF) and tumor necrosis factor alpha…
- Trial name
- NCT02750956
- Testing
- Non-surgical periodontal treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Growth Hormone Deficiency With Pituitary Anomalies
Validation of Macimorelin as a Test for Adult Growth Hormone Deficiency
The Macimorelin Growth Hormone Stimulation Test (GHST) will be compared with the Insulin Tolerance Test (ITT) in an open-label, randomized, 2-way crossover Trial.
- Trial name
- NCT02558829
- Testing
- Macimorelin, Insulin
- Where
- 27 sites in United States, Austria and 7 more
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- AEterna Zentaris
Infant Malnutrition, Cognitive Change
Integrating Infant Feeding Counselling With Psychosocial Stimulation to Improve Child Growth and Development in Urban Slum of Bangladesh
Undernutrition and poor cognitive development affect many children under 5 in developing countries, who are exposed to multiple risk factors including poverty, malnutrition, poor health, and unstimulating home environments.
- Trial name
- NCT03040375
- Testing
- Peer counselling
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh