Clinical trials: Growth Disorders
Growth Hormone Deficiency, Traumatic Brain Injury
Charactertizing Growth Hormone Deficiency in Traumatic Brain Injury
The goal of this observational study is to characterize the impact of growth hormone deficiency (GHD) on quality of life, symptom burden, and sleep in adults with traumatic brain injury (TBI), and to evaluate whether these…
- Trial name
- NCT07795736
- Testing
- Not applicable (observational study)
- Where
- 2 sites in Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Prevention of Vitamin Deficiency During and/or Before Pregnancy
A Study to Gather Information About the Progress and Outcomes of Pregnancy in Women Using Various Vitamin Support Plans Before and During Pregnancy
This is an observational study in which data from the participants who will be taking different vitamin supplementation regimes before and during pregnancy.
- Trial name
- NCT05062044
- Testing
- Multivitamins (Elevit, BAY987808), Multivitamins (Elevit, BAY2906300), Multivitamins (Elevit, BAY987386)
- Where
- 3 sites in Kazakhstan, Russia and 1 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Bayer
Autism Spectrum Disorder, Language Development
Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning
The goal of this observational study is to test a reciprocal relationship between statistical learning and the development of language and literacy in first-graders with autism and their non-autistic peers.
- Conditions
- Autism Spectrum Disorder, Language Development, Literacy
- Trial name
- PLAUSL (NCT06332144)
- Testing
- Structural vs. Random sequences of stimuli, Intact vs. Degraded speech, Repeating 5-syllable nonwords or 2-syllable nonwords
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Dental Implant, Bone Loss
Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor
This study will compare two techniques to achieve increase in ridge dimensions as a preparation for dental implants using a resorbable barrier membrane and bone particulate allogenic graft hydrated with saline or a growth factor…
- Trial name
- NCT04954664
- Testing
- Allograft particles hydrated with rhPDGF, Allograft particles hydrated in a conventional way with saline.
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Diarrheal Illnesses, Respiratory Illness
A Trial of Zinc and Micronutrients in Tanzanian Children
A randomized clinical trial of multiple micronutrients, zinc, zinc + micronutrients, or placebo among 2400 children born to HIV-negative Tanzanian mothers.
- Conditions
- Diarrheal Illnesses, Respiratory Illness, Growth Faltering
- Trial name
- NCT00421668
- Testing
- Zinc, Multivitamins
- Where
- Tanzania
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Growth Retardation
Intervention in Minimizing Aflatoxins and Fumonisins Exposure to Children Through Food and Breastfeeding in Tanzania
It has been shown that exposure to mycotoxins through complementary foods and breast milk had profound effects on growth of children from 6 months to 1 year of age.
- Trial name
- NCT02438774
- Testing
- post-harvest intervention package, Routine agriculture extension services
- Where
- 3 sites in Tanzania
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tanzania Food and Drugs Authority
Stillbirth, Infant, Low Birth Weight
UniSA BackOff! Study: Adelaide PrenaBelt Trial
Stillbirth (SB) is a devastating complication of pregnancy and contributes to over 2 million deaths globally every year. Over 20 million infants are born every year with low birth weight (LBW), which is associated with a twenty…
- Conditions
- Stillbirth, Infant, Low Birth Weight, Infant, Very Low Birth Weight, Sleep-Disordered Breathing
- Trial name
- NCT04437407
- Testing
- PB2-1 prototype, PB2-2 prototype, PB2-3 prototype
- Where
- Australia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Pre-Eclampsia, Pre-Term
Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes
Women who had an adverse pregnancy outcome (APO), such as preeclampsia, preterm birth, or gestational diabetes, have a higher risk for heart disease.
- Conditions
- Pre-Eclampsia, Pre-Term, Intrauterine Growth Restriction, Hypertension in Pregnancy
- Trial name
- VIA (NCT04633551)
- Testing
- Anti-inflammatory supplement
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Newborn; Vitality, Sleep
Effects of Kangaroo Care on Circadian Rhythm, Growth and Physiological Effects
This study was planned to investigate the effect of premature babies receiving regular kangaroo care in the NICU on circadian rhythm, growth and physiological parameters, and breast milk cortisol levels
- Conditions
- Newborn; Vitality, Sleep, Preterm Labor, Care Pattern, Maternal
- Trial name
- NCT06589349
- Testing
- Kangaroo Care
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Sibel Küçükoğlu
Alveolar Osteitis, Impacted Tooth
Effect of CGF on Frequency of Alveolar Osteitis Following Partially Erupted Mandibular Third Molar Surgery
The aim of this prospective study was to assess the effectiveness of concentrated growth factors (CGFs) in preventing the development of alveolar osteitis (AO) after the extraction of partially-erupted mandibular third molars.
- Trial name
- NCT04151147
- Testing
- Concentrated Growth Factor (Test group), Non-Concentrated Growth Factor (Control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ege University
Insulin Resistance, Obesity & Overweight
Effects of Ketone Bodies on Insulin Sensitivity
KETO-SENSE is a clinical research study investigating how ketone bodies affect energy metabolism and insulin sensitivity in humans.
- Conditions
- Insulin Resistance, Obesity & Overweight, Energy Metabolism, Ketone Body Metabolism
- Trial name
- KETO-SENSE (NCT07359625)
- Testing
- Growth Hormone, Human, Oral ketone supplement (KetoAid®, KE4)
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Periodontitis, Periodontal Attachment Loss
T-PRF Provides Advantages on Periodontal Healing: A Split Mouth Clinical Study
It was aimed to evaluate the contributions of T-PRF treatment combined with open flap debridement on biological markers in GCF and periodontal outcomes in chronic periodontitis patients.
- Trial name
- NCT03027050
- Testing
- T-PRF, Open Flap Debridement alone
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Periodontal Diseases
Impact of Periodontal Treatment on Growth Differentiation Factor-15 Levels
In light of the controversy that are already approved but that however still exists regarding the efficacy and influence the management of Periodontitis, the aim of this study was to evaluates, at 6-months follow-up, the…
- Trial name
- NCT05720481
- Testing
- Full mouth Scaling and root planing, Quadrant Scaling and root planing
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Catania
Hashimoto Disease
FGF-21 Levels and RMR in Children and Adolescents With Hashimoto's Thyroiditis (THYROMETABOL)
It is well documented that thyroid hormones (THs) are involved in energy and lipid metabolism, thermogenesis, and body weight control, acting on several tissues.
- Trial name
- THYROMETABOL (NCT02725879)
- Where
- Greece
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Pregnancy, Fetal Macrosomia
Correlation Between Placental Thickness in the Second and Third Trimester and Fetal Weight
The aim of this prospective longitudinal study was to investigate the relationship between placental thickness during the second and third trimesters and placental and birth weights.
- Conditions
- Pregnancy, Fetal Macrosomia, Intrauterine Growth Restriction
- Trial name
- NCT02473991
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Androgenetic Alopecia
A Phase 2a Trial of FOL-005 Topical Formulations to Investigate Hair Growth Potential and Safety in Healthy Male Volunteers
This exploratory phase IIa, double blind, randomized, vehicle controlled, multicenter dose-finding trial will evaluate the safety, tolerability, and efficacy of FOL-005 topical formulation (at 0.1%, 0.5% and 1.5% strength)…
- Trial name
- NCT04774874
- Testing
- Topical formulation
- Where
- Germany
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Follicum AB
Mobile Health, Healthy
A mHealth Based Education Intervention on Maternal, Infant and Young Child Nutrition to Prevent Stunting in Kelantan
This research aimed to develop health module related to nutrition through mobile phone and to access it effectiveness among mother, infant and children (0-2 years old) to prevent stunting in Kelantan, Malaysia.
- Trial name
- stunting (NCT04606706)
- Testing
- Mobile health nutrition education intervention
- Where
- Malaysia
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Growth Hormone Disorder, Healthy
Dose Study in Healthy Japanese Males Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083
This trial is conducted in Europe. The aim of this clinical trial is to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of a NNC126-0083 in healthy male Japanese subjects.
- Trial name
- NCT00722540
- Testing
- NNC126-0083
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Depression, Anxiety
Image Narrative With College Students
The PI developed the Image Narrative Intervention (INI) based on the research using visual images in which visual images and narratives were found to support trauma survivors in narrating their experiences and in meaning making.
- Trial name
- NCT04759313
- Testing
- Image Narrative
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Utah
Infant Development
European Childhood Obesity Project: Early Programming by Infant Nutrition?
Primary hypothesis to be tested: Early protein intake predicts infant growth and later risk of childhood obesity. Childhood obesity is a major public health problem and is an identified priority concern for the health care.
- Trial name
- CHOP (NCT00338689)
- Testing
- Lower protein formula; Higher protein formula
- Where
- 5 sites in Belgium, Germany and 3 more
- Volunteers
- 1,678 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich