Clinical trials: Guided Bone Regeneration
Alveolar Bone Resorption
LPRF Block vs. DBBM in Horizontal Bone Reconstruction
split-mouth RCT. 12 patients. horizontal GBR performed. 2 grafts were compared: test was LPRF block, control was 50% autogenous bone and 50% DBBM. 25 months follow-up.
- Trial name
- NCT07584629
- Testing
- guided bone regeneration
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Implant Placement in Maxillary Esthetic Zone
Evaluation of Bone Regeneration Outcomes Following Guided Bone Regeneration in the Anterior Maxillary Region
1. Research background: Guided bone regeneration (GBR), as a bone augmentation technique, is widely used for reconstructing hard tissue defects in implant placement in the anterior esthetic zone.
- Trial name
- NCT07851129
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fuming He
Guided Bone Regeneration, Dental Implant
RCT GBR One Stages Comparing A-Oss and Autogenous Bone Versus A-Oss and LCR-A
The aim of this randomized controlled trial is to evaluate the tridimensional bone stability after horizontal one-stage GBR using collagene membrane (OssMem) with a mix of Bovine Bone Substitute (A-Oss) and autogenous bone (test…
- Trial name
- NCT06286605
- Testing
- A-oss and autogenous bone, A-oss an LCR-A
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Guided Bone Regeneration
Clinical Efficacy Assessment of Digitally Fabricated PEEK Barrier Membranes for Guided Bone Regeneration in Severe Bone Defects
1. Research background: Guided bone regeneration (GBR), as a bone augmentation technique, is widely used for the reconstruction of hard-tissue defects in implant dentistry.
- Trial name
- NCT07918131
- Testing
- PEEK barrier membrane
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Fuming He
Bone Deformity
The Influence of 3D Surgical Template on the Contour of Bone Augmentation, in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation
Evaluate the impact of using 3D surgical template with guided bone regeneration technique on the contour of bone augmentation in patients with horizontal labial ridge defect and simultaneous implantation.
- Trial name
- NCT06312384
- Testing
- 3D Surgical Template on the Contour of Bone Augmentation, in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation, conventional guided bone regeneration,in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Ridge Enlargement, Fenestration
Histological Analysis of Osteogenic Potential of Biphasic Calcium Phosphate
Bone healing after tooth extraction may be affected by defects in the buccal wall of the alveolus, such as fenestrations and dehiscences.
- Conditions
- Alveolar Ridge Enlargement, Fenestration, Dehiscence
- Trial name
- NCT06020092
- Testing
- Bone augmentation with I-BCP, Bone augmentation with BX
- Where
- Croatia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Bone Resorption
Guided Bone Regeneration Using Bovine-derived Xenograft in Combination With or Without Injectable Platelet-rich Fibrin
The aim of the study was to compare the change in augmentation thickness after guided bone regeneration (GBR) using bovine-derived xenograft in combination with or without injectable platelet-rich fibrin (i-PRF).
- Trial name
- NCT04709523
- Testing
- bovine-derived xenograft with i-PRF, bovine-derived xenograft alone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Horizontal Ridge Deficiency
Evaluation of Bone Regenerated With Guided Bone Regeneration (GBR) Using Polymethylmethacrylate (PMMA) Membrane
To evaluate the quantity and quality of bone generated, radiographically and histomorphometrically, after guided bone regeneration (GBR) using a membrane of 3D printed custom made (PMMA) and subsequent stability of delayed…
- Trial name
- NCT06186232
- Testing
- guided bone regeneration (GBR).
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Process
Evaluation of a Synthetic Bone Substitute for Ridge Preservation
Fifteen patients were selected, each presenting at least two jaw front teeth indicated for extraction: in the Test Group (TG), post-extraction sockets was filled by synthetic bone substitute ReproBone, and in the Control Group…
- Trial name
- NCT02894528
- Testing
- BioMend and ReproBone, BioMend without ReproBone
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Alveolar Bone Loss, Pathological Conditions, Anatomical
Comparison of Amnion Chorion Membrane vs. Dense Polytetrafluoroethylene Membrane in Ridge Preservation Procedures
The purpose of this study is to examine if a biologically active commercially available amnion chorion membrane (ACM) is as effective as the commercially available inert dense polytetrafluoroethylene membrane (D-PTFE) in…
- Trial name
- NCT02602223
- Testing
- Placing Amnion chorion membrane over grafted site, Placing d-PTFE membrane over grafted site
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dental Implant, Narrow Implant
Comparison Between Ultra-narrow Diameter Implants (2,75 mm) Without Bone Regeneration Versus Standard Diameter Implants (4,3 mm) in Combination With Bone Regeneration
The main target of the study is to compare ultra-narrow diameter implants (2.75 mm) without bone regeneration versus standard diameter implants (4.3 mm) in combination with bone regeneration.
- Conditions
- Dental Implant, Narrow Implant, Implant Fracture, Guided Bone Regeneration
- Trial name
- NCT03225495
- Testing
- Standard implant, Ultra-narrow implant
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Guided Bone Regeneration
Impact of Gingival Phenotype on Guided Bone Regeneration in the Maxillary Anterior Region
Research background: Guided bone regeneration (GBR), as a bone augmentation technique, is widely used for reconstructing hard tissue defects in implant placement in the anterior esthetic zone.
- Trial name
- NCT07918118
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fuming He
Missing Tooth, Fractured Tooth
Radiographic and the Esthetic Outcome of Two Different Bone Grafting Techniques in Early Implant Placement
Total of 48 subjects were randomly assigned to treatment groups: UT Health Science Center at San Antonio Chi Mei Medical Center, Tainan, Taiwan Patients require a maxillary non-molar extraction site that is planned to be replaced…
- Trial name
- NCT03302143
- Testing
- Guided bone regeneration with Bovine Bone Mineral, Guided bone regeneration with freeze dried bone allograft
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Peri-Implantitis
Guided Bone Regeneration of Peri-implant Defects Comparing Submerged Versus Non-submerged Healing
Objective: the objective of the present randomized clinical trial is to compare changes in radiographic peri-implant bone defect fill after regeneration of peri-implant intrabony defects with a submerged versus a non-submerged…
- Trial name
- NCT03900741
- Testing
- Submerged healing, Non-submerged healing
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ana Molina Villar
Periodontal Diseases, Periodontal Bone Loss
3D Printed Customized Bone Graft for Alveolar Regeneration: Longitudinal Cohort Evaluation
This study will evaluate the behavior of the implant-supported restorations (prosthesis) placed into the areas grafted with the 3D printed customized bone (personalized graft produced to fit a specific bone defect), as well as…
- Trial name
- NCT07405918
- Testing
- Clinical evaluation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Alveolar Ridge Augmentation
Lateral Ridge Augmentation Using Allograft Blocks and GBR for Implant Sites
Clinicians are increasingly faced with the challenge of reconstructing the alveolar ridge as more patients desire fixed implant-supported restorations.
- Trial name
- NCT03879967
- Testing
- Allograft block graft
- Where
- Switzerland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Bern
Alveolar Process Defect
Ridge Augmentation Comparing a Block Allograft to a Demineralized Bone Matrix Allograft.
This study with compare the ridge dimension changes for a block allograft vs. a demineralized bone matrix moldable allograft.
- Trial name
- NCT02127112
- Testing
- Block Allograft plus Matrix Allograft, Moldable Matrix Allograft
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Ridge Splitting, Simvastatin
The Effect of Simvastatin With Guided Bone Regeneration in Ridge Splitting and Simultaneously Implantation
Ridge split augmentation technique, with immediate implant placement, reduces the time of the treatment and the time of the final prosthetic reconstruction. Furthermore, compression of the bone increases its density.
- Conditions
- Ridge Splitting, Simvastatin, Immediate Implant
- Trial name
- NCT05020405
- Testing
- Immediate implant placement and ARS with GBR and SMV, Immediate implant placement and ARS with GBR
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Ridge Preservation
Impact of PTFE-d Barrier Intentionally Exposed to Bucal Environment in Guided Bone Regeneration to Ridge Preservation
The aim of this clinical-laboratorial, paralel, randomized, prospective and controlled study was determine the impact of of PTFE-d barrier intentionally exposed to bucal environment in guided bone regeneration to ridge…
- Trial name
- NCT04329351
- Testing
- Guided Bone regeneration
- Where
- 2 sites in Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fernanda Vieira Ribeiro
Dental Implant, Immediate Implant
Artificial Intelligence-Guided Versus Manual CBCT Planning for Immediate Implant Placement
This study evaluates whether artificial intelligence (AI)-based analysis of cone-beam computed tomography (CBCT) scans can support clinical decision-making for immediate dental implant placement in molar extraction sites.
- Conditions
- Dental Implant, Immediate Implant, Guided Bone Regeneration
- Trial name
- AI (NCT07459036)
- Testing
- AI assisted CBCt, Manual CBCT segmentation
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shalash Dental education