Clinical trials: Gum Disease
Tooth Loss, Ceramic Implant
PMCF Study of CeraRoot Ceramic Implants One-piece: 3 Years Follow up
The main objective is to evaluate the success / failure rate of CeraRoot ceramic implants (one piece) during three year follow up.
- Trial name
- NCT04598776
- Where
- Spain
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- CeraRoot SL
Gingivitis
A Follow-Up Survey of Oral Hygiene and Health Outcomes for Women Previously Enrolled in "OHMOM"
The objective of this study is to assess oral health, oral hygiene knowledge, and daily oral hygiene practices of women who participated in a randomized controlled trial (2011001) at University of Alabama Birmingham during the…
- Trial name
- OHBABY (NCT02922010)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Periodontal Diseases, Periodontitis
An Evaluation of the Effect of the Erchonia FX-405 Laser as an Adjunctive Treatment of Periodontitis
The purpose of this clinical study is to determine the effectiveness of the Erchonia® FX-405 (manufactured by Erchonia Corporation (the Company) in providing a noninvasive adjunctive treatment in combination with periodontal…
- Conditions
- Periodontal Diseases, Periodontitis, Gum Disease
- Trial name
- NCT06656325
- Testing
- Erchonia® FX405
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Erchonia Corporation
Peri-implantitis
Long-term Follow-up Observation After Surgical Treatment of Peri-implantitis in Multicenter Post Market Clinical Study
The objective of this non-interventional long-term follow-up observation is to evaluate the long-term sustainability of two surgical treatments of peri-implantitis with and without Geistlich Bio-Oss® and Geistlich Bio-Gide® from…
- Trial name
- NCT03776097
- Testing
- observational study
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Geistlich Pharma AG
Periodontitis
Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis
The purpose of this study is to measure the antimicrobial effects of Arestin in subjects with moderate to advanced periodontal disease
- Trial name
- NCT00371332
- Testing
- Minocycline HCL Microspheres
- Where
- 5 sites in United States
- Volunteers
- 128 people
- Sponsor
- OraPharma
Gingival Diseases
Compare the Clinical Efficacy of Prototype Toothpastes.
Evaluate clinical efficacy of a prototype toothpaste on control of dental plaque gingival inflammation
- Trial name
- NCT00761930
- Testing
- Fluoride, Triclosan and fluoride, Herbal Ingredient and fluoride
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
Clinical Study Examining the Control of Plaque and Gingivitis
The objective of this six-month clinical investigation is to evaluate the efficacy of a silica-free meridol toothpaste versus Colgate Cavity Protection Toothpaste in the control of established dental plaque and gingivitis.
- Trial name
- NCT07842978
- Testing
- Silica Free Meridol, Meridol, Colgate Dental Product
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Demineralization
Impact of Chewing Gum With CPP-ACP on Tooth Mineralisation in Situ
Monocentric, randomised, double-blind, cross-over controlled study with two arms. This study aims to analyse the impact on mineralisation of Sugar Free Gum (SFG) containing CPP-ACP in healthy adults.
- Trial name
- NCT03971084
- Testing
- Sugar free gum without CPP-ACP, Sugar free gum with CPP-ACP
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Gingivitis
Clinical Investigation of PerioGard (Test) Regimen
The objective of this three-month clinical research study is to evaluate the clinical efficacy of the PerioGard (test) regimen (0.45% SnF-HW Toothpaste, CPC-Zinc-Fluoride Mouthwash, Gummy Toothbrush) compared to the control…
- Trial name
- NCT07210138
- Testing
- PeriGuard regimen, Colgate Dental Cream regimen
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Peri Implant Mucositis, Peri Implantitis
Study on the Treatment of Dental Implants Using the AmbiJet System for Peri-implantitis and Peri-implant Mucositis
Inflammation of the tissue surrounding a dental implant (peri-implantitis or peri-implant mucositis) can lead to implant loss in advanced stages.
- Trial name
- AmbiJet-FIH (NCT07722715)
- Testing
- AmbiJet cold plasma system, Standard Mechanical Debridement (S3 Guideline)
- Where
- Ukraine
- Volunteers
- 26 people
- Sponsor
- Freiburger Medizintechnik GmbH
Dental Plaque
Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals
The purpose of the study is to assess the effect of enzyme containing lozenges on dental plaque accumulation in healthy adults.
- Trial name
- NCT05082103
- Testing
- Enzyme lozenge 1, Enzyme lozenge 2
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Osteoarthritis, Knee
FiH Safety and Feasibility Study Assessing Intra-articular Administration of aeGF in Patients With Knee Osteoarthritis
The company funding this study has developed an advanced therapy medicinal product (a cell therapy) from human donor cells which it wants to assess as a possible treatment for knee osteoarthritis (OA).
- Trial name
- NCT06690710
- Testing
- allogeneic engineered Gingival Fibroblasts (aeGF)
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Scarcell Therapeutics S.A.S.
Gingivitis
A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers
The purpose of this study is to investigate the effectiveness of usage of a range of oral products (toothpaste, mouth rinse, denture cleanser) on the oral health of partial denture wearers compared to existing oral hygiene…
- Trial name
- NCT04290624
- Testing
- Experimental Dentifrice: Stannous Fluoride, COREGA Denture Foaming Cleanser, Mouth rinse: Sodium Fluoride
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- HALEON
Gingivitis
Meta-analysis of Stannous Fluoride and the Effects on Gingival Health
The aim of this 18 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) dentifrices when used up to 3 months on gingivitis relative to a positive or negative control dentifrice.
- Trial name
- NCT03970759
- Testing
- Stannous Fluoride Dentifrice, Positive control dentifrice, Negative control dentifrice
- Where
- United States
- Volunteers
- 2,890 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Tooth Loss
A Clinical Study of the TSX Dental Implant System (Xpresso)
A prospective, observational, multicenter study where 62 patients needing implants in the maxilla or mandible will be enrolled. The patients will be restored with a final prosthesis no later than 4 months following implant…
- Trial name
- Xpresso (NCT06571812)
- Testing
- TSX
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- ZimVie
Dental Calculus
Testing if Tartarase Can Remove Dental Tartar
This study was designed to find our whether a novel toothpaste containing safe digestive enzymes (Tartarase) was able to remove pre-existing dental tartar when compared to a well-known toothpaste (Crest).
- Trial name
- NCT06139835
- Testing
- Tartarase
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pontis Biologics, Inc.
Plaque, Dental, Gingivitis
Evaluation of Toothbrush Bristles in Plaque Reduction
The purpose of this cross-over clinical research is to evaluate the cleaning efficacy of toothbrushes tufted with two types of tapered bristles and end rounded bristles in removal of interdental plaque with clinical measurement…
- Trial name
- NCT04681885
- Testing
- Tapered bristles A, Tapered bristles B, End rounded bristles
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sunstar Americas
Periodontitis, Dental Plaque
At-Home Care for Subjects With Periodontitis
The effect of use of powered toothbrushing in patients exhibiting periodontal inflammation has been observed repeatedly in clinical studies conducted over a 20+ year period.
- Trial name
- NCT04254770
- Testing
- ADA approved Manual Toothbrush, Marketed Power Toothbrush
- Where
- United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Tooth Loss
A Comparative, Randomized, Prospective, Performance Evaluation of Abutments in Single Tooth Gaps
Immunologically evaluation of myeloperoxidase level as indicator for inflammatory reactions on modified surface abutments compared to machined surface abutments.
- Trial name
- NCT02219139
- Testing
- ESTA abutment Roxolid
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Institut Straumann AG
Peri-Implantitis
Comparing Two Treatment Modalities of Peri-implantitis - Blue Laser (445 nm) and Conventional Flap Surgery
A clinical trial comparing laser treatment and conventional mucosal flap surgery for treatment of peri-implantitis. The main aim of the study is to evaluate if treatment of peri-implantitis with a novel blue laser (445 nm)…
- Trial name
- NCT03624257
- Testing
- Laser treatment, Mucosal flap surgery
- Where
- 2 sites in Sweden
- Sponsor
- Sirona Dental Systems GmbH