Clinical trials: Gynaecologic Cancer
Education, Surgery
Video-based Coaching (VBC) in Gynecologic Surgery
This multi-centre, randomized controlled trial aims to assess the role of video-based coaching (VBC) in residency education in gynecologic and gynecologic oncology surgery.
- Conditions
- Education, Surgery, Gynecologic Cancer
- Trial name
- NCT05086783
- Testing
- Video-based coaching, Standard surgical teaching (master-apprentice model - (MAM))
- Where
- 3 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Surgical Site Infection, Surgical Complication
Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery
The purpose of this study is to investigate whether the use of a preoperative antibiotic bowel regimen is associated with a reduced risk of deep organ/space surgical site infection in gynecologic oncology surgery.
- Conditions
- Surgical Site Infection, Surgical Complication, Gynecologic Cancer
- Trial name
- NCT05210556
- Testing
- Diagnosed with Surgical Site Infection
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Gynecologic Cancer
Assessment of Sexual Dysfunction, Depression and Anxiety in Underserved, Minority Gynecologic Cancers Patients
Objectives: Assess the prevalence and severity of depression and anxiety in underserved and minority women seen in the gynecologic oncology clinic at Lyndon Baines Johnson General Hospital.
- Trial name
- NCT01031602
- Testing
- Surveys
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Gynecologic Cancer
Impact of Cultural and Linguistic Backgrounds on Patient Care and Experience of Women With Gynecologic Malignancies
Purpose of this study to delineate the attitudes and experiences of patients, interpreters and cancer care professionals involved in the care of oncology patients with gynecologic malignancies with cultural and linguistic…
- Trial name
- iCALD-2 (NCT05971303)
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Weight Gain
Efficacy of Olanzapine on Weight Gain in Advanced Gynecologic Cancer with Paclitaxel and Carboplatin: a Double Blind, Placebo-controlled Randomized Trial
Efficacy of olanzapine on weight gain in advanced stage gynecologic cancer Proprotion of pateints in advanced stage gynecologic cancer who recieving paclitaxel and carboplatin chemotherapy gain weight on olanzapine or placebo
- Trial name
- NCT06288854
- Testing
- weight gain each group
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Gynecologic Cancer, Breast Cancer
Web-based Family History Tool
The purpose of this pilot study is to determine if a web-based tool that collects family health history is useful for patients being seen in a gynecologic oncology office setting.
- Conditions
- Gynecologic Cancer, Breast Cancer, BRCA1 Mutation, BRCA2 Mutation
- Trial name
- Progeny (NCT04890327)
- Testing
- Web-based family health history tool
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Emotional Assessment, Nursing
Emotional Assessment and Tiered Individualized Psychological Support of the Artificial Intelligence Robot
To develop the E-MOTE robot and evaluate its effectiveness in addressing psychological distress, physical symptom, stress index, and quality of life, as well as to explore its clinical applicability.
- Conditions
- Emotional Assessment, Nursing, Gynecological Cancers
- Trial name
- NCT07365761
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Gynecologic Surgical Procedures, Enhanced Recovery After Surgery
Prehabilitation Plus ERAS vs ERAS in Gynecological Surgery
Prospective, interventionist, controlled and randomized study to test the effectiveness of multimodal prehabilitation protocol in patients who will undergo gynecological surgery.
- Trial name
- NCT04505111
- Testing
- Prehabilitation Program + Enhanced Recovery After Surgery, Enhanced Recovery After Surgery
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Controle do Cancer
Anxiety Disorders
Impact of Preoperative Counseling and Education in Reducing Anxiety Levels in Patients With Gynecologic Tumors
The surgical procedure can be considered a transition in the patient's life. The transition can generate instability and produce negative effects, which may be temporary or permanent.
- Trial name
- NCT03574155
- Testing
- Pre-operative Counseling and Education
- Where
- Brazil
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Barretos Cancer Hospital
Breast Cancer, Leukemia
Delayed Effects of Treatment in Cancer Survivors (DETECS)
Hypotheses and Specific Aims: There is limited data on the long-term consequences of cancer therapy on young, reproductively aged cancer survivors.
- Conditions
- Breast Cancer, Leukemia, Lymphoma, Gynecologic Cancer
- Trial name
- DETECS (NCT02067637)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Gynecologic Cancer
Evaluation of a Brachytherapy Discharge Education Program to Improve Patient Care
Although brachytherapy is an effective treatment modality for gynecological cancer, a significant proportion of patients develop late treatment-related vaginal toxicity, negatively impacting their quality of life and limiting…
- Trial name
- BrachDEP (NCT04707937)
- Testing
- Online education, Regular standard of care education
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Paralytic Ileus, Nausea
The Impact of Preoperative Bowel Exercise on Postoperative Bowel Functions in Gynecologic Malignancies
Gastrointestinal dysfunction is a common complication after abdominal gynecologic oncology surgery. There are numerous studies in the literature addressing the management of bowel function in the postoperative period.
- Conditions
- Paralytic Ileus, Nausea, Defecation Disorder
- Trial name
- IPBEPOBF (NCT06113718)
- Testing
- Abdominal Exercise (digital rectal stimulation, abdominal massage)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Ovarian Cancer
Bone Health in Gynecologic Cancers-does FOSAVANCE Help?
Women who undergo bilateral oophorectomy and receive chemotherapy are at risk of increased bone loss. At present, despite having a risk factor profile that fits the indications for assessment and treatment there are no routine…
- Trial name
- FOSAVANCE (NCT00593580)
- Testing
- alendronate/cholecalciferol
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Financial Burden, Financial Toxicity
Proactive Costs of Care Study
The Proactive Costs of Care intervention is an educational intervention designed to help patients deal with the cost of cancer care.
- Conditions
- Financial Burden, Financial Toxicity, Financial Stress, Financial Navigation
- Trial name
- PCOC (NCT07217262)
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Cancer, Cancer Metastatic
The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors
The purpose of this prospective, interventional, single-arm pilot study is to evaluate whether virtually delivered group-based physical activity is feasible for adolescent and young adult (AYA) cancer survivors.
- Conditions
- Cancer, Cancer Metastatic, Neoplasms, Breast Cancer
- Trial name
- NCT05131815
- Testing
- Virtual group based physical activity (BurnAlong) and Social Media Discussion Board
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Gynecologic Disease, Gynecologic Cancer
Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology
GynRAN is an international, multicentre, transversal, diagnostic and non-interventional study carried out in gynecology-obstetrics/gynecological oncology departments that aims to identify a diagnostic signature for gynecological…
- Conditions
- Gynecologic Disease, Gynecologic Cancer, Endometriosis, Ovarian Cancer
- Trial name
- GynRNA (NCT06392997)
- Testing
- Saliva sample
- Where
- 13 sites in France
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- ZIWIG
Intraocular Pressure, Oncology
Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients
Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in…
- Trial name
- NCT04281017
- Testing
- TIVA, Balanced anesthesia
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Postoperative Pain, Postoperative Nausea and Vomiting
Surgical Site Infiltration of Exparel vs TAP Block With Exparel in Patients Undergoing Laparotomy Via Midline Incision
This is a randomized-controlled prospective study to be conducted at Danbury Hospital and Norwalk Hospital to compare postoperative opioid consumption and pain scores of patients with suspected or known gynecologic malignancies…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Opioid Use
- Trial name
- NCT03870685
- Testing
- TAP Block, Surgical Site Infiltration, Exparel
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Danbury Hospital
Nursing, Gynecological Cancers
Effects of a Self-Regulation Based E-MOTE Program Delivered Via an AI-Assisted Robot and Supported by Mobile Platforms for Newly Diagnosed Gynecologic Cancer Patients
To evaluate the effectiveness of the E-MOTE Emotional Care Program, delivered through the Kebbi robot and the LINE Official Account, for patients newly diagnosed with gynecologic cancer undergoing surgery.
- Conditions
- Nursing, Gynecological Cancers, Psycho-Oncology
- Trial name
- NCT07745478
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Digestive System Carcinoma, Genitourinary System Carcinoma
Home Base Telemonitoring in Gastrointestinal, Genitourinary, or Gynecologic Cancer Patients Undergoing Abdominal Surgery
This phase III trial compares a home-based telemonitoring program that collects symptom and daily step information to surgeon only care in improving recovery and stopping complications within 30 days after surgery in patients…
- Conditions
- Digestive System Carcinoma, Genitourinary System Carcinoma, Malignant Female Reproductive System Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04596384
- Testing
- Best Practice, Functional Assessment, Medical Device Usage and Evaluation
- Where
- 3 sites in United States
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center