Clinical trials: Gynaecological Cancer
Pelvic Cancer
A Review of Functional and Surgical Outcomes of Gynaecological Reconstruction in the Context of Pelvic Exenteration
Patients with locally advanced pelvic malignancy undergo radical procedures, necessitate organ reconstruction. Little is known about the preferred methods of gynaecological organ reconstruction in the context of pelvic…
- Trial name
- NCT05074069
- Testing
- Gynaecological reconstruction
- Where
- Ireland
- Volunteers
- 334 people
- Sponsor
- St Vincent's University Hospital, Ireland
Gastrointestinal Cancer, Prostate Cancer
Study to Evaluate the Clinical Benefit Response in Cancer Patients With Advanced Disease With AMT2003 Versus Placebo
The purpose of the study is to evaluate the efficacy and the safety of AMT2003 in cancer patients with advanced disease. The primary evaluation criterion is clinical benefit response.
- Conditions
- Gastrointestinal Cancer, Prostate Cancer, Genital Neoplasms, Female
- Trial name
- NCT00332280
- Testing
- AMT2003
- Where
- 2 sites in Bosnia and Herzegovina, Germany
- Volunteers
- 67 people
- Sponsor
- Auron Healthcare GmbH
Gynecologic Cancer
To Explore the Benefits of the MonaLisa Touch® System in Gynaecological Cancer Patients Treated by (Chemo)-RT
The increasing survival rate of gynaecological cancer patients highlights the need to improve their Quality of Life (QoL) after treatment.
- Trial name
- SQUAL (NCT05891470)
- Testing
- MonaLisa Touch device, Vaginal dilatators
- Where
- Belgium
- Volunteers
- 136 people
- Sponsor
- Jules Bordet Institute
Gynaecological Cancers
ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological Cancers With ARId1A Loss or no Loss
ATARI trial tests the ATR inhibitor drug ceralasertib (AZD6738) alone and in combination with either a PARP inhibitor drug called olaparib, or an anti-PD-L1 immunotherapy called durvalumab (MEDI4736) in patients with relapsed…
- Trial name
- ATARI (NCT04065269)
- Testing
- Ceralasertib, Olaparib, Durvalumab
- Where
- 9 sites in Canada, United Kingdom
- Volunteers
- 174 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Gynecological Cancer
Low-Intensity CBT for Gynaecological Cancer Survivors
There are 21,500 gynaecological cancers diagnosed in the UK each year. These are often diagnosed later than common cancers, which is predictive of low survival and high psychological distress.
- Trial name
- EPELIT (NCT03553784)
- Testing
- Group delivered Low Intensity Cognitive Behavioural Therapy
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Chester
Lymph Node Cancer Metastatic
High Dose SBRT for Abdominal-Pelvic Lymph Nodal Lesions in Oligometastatic Patients
This is a prospective, multicentric, phase II and feasibility study aimed to address early and late side effects of hypofractionated ablative radiotherapy for oligometastatic patients with lymph node metastases for…
- Trial name
- NCT02570399
- Testing
- Oligometastatic patients with abdominal-pelvic lymph nodes
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Lower Extremity Lymphedema
Daphnetin Capsules for Lower Limb Lymphoedema Following Gynaecological Surgery
This clinical trial is designed to learn more about treating patients with lower limb lymphoedema following gynaecological surgery.
- Trial name
- NCT06329167
- Testing
- Daphnetin, Aescuven
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Hospital of Jilin University
Abdominal Hysterectomy (& Wertheim)
Hysterectomy for Benign Gynaecological Conditions With or Without Tubectomy
The purpose of this study is to determine whether a tubectomy during hysterectomy for benign gynaecological conditions does not result into a premature menopause.
- Trial name
- HYSTUB (NCT02281487)
- Testing
- Hysterectomy plus Tubectomy, Hysterectomy, light microscopy
- Where
- 5 sites in Netherlands
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Gynaecologisch Oncologisch Centrum Zuid
Morbidity, Gynaecologic Cancer
Blood Lactate Level With Paraaortic Lymph Node Dissection
This study was designed as a prospective observational study.
- Trial name
- NCT06648330
- Testing
- Paraaortic retroperitoneal lymph node dissection
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Duygu Akyol