Clinical trials: Gynaecological Cancers
Morbidity, Gynaecologic Cancer
Blood Lactate Level With Paraaortic Lymph Node Dissection
This study was designed as a prospective observational study.
- Trial name
- NCT06648330
- Testing
- Paraaortic retroperitoneal lymph node dissection
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Duygu Akyol
Gynaecologic Cancer
Impact of Peritoneal Gas Drain on Postoperative Pain for Gynaecological Cancer Patients With Minimally Invasive Surgery
This is a phase III, monocenter and randomized study, which evaluates the effectiveness of peritoneal gas drainage on postoperative pain in laparoscopic or robotic laparoscopic gynaecological surgery.
- Trial name
- DRAIN-EXSU (NCT04974125)
- Testing
- Drain, Manual exsufflation
- Where
- France
- Volunteers
- 202 people
- Sponsor
- Centre Oscar Lambret
Prostate Cancer, Gynaecological Cancer
In Vivo Dosimetry for Brachytherapy Study
The main study aim is the investigate the clinical use of in vivo dosimeters (small measurement devices) for brachytherapy (internal radiotherapy).
- Trial name
- NCT06863090
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- East and North Hertfordshire NHS Trust
Peripheral Blocs
Transversus Abdominis Plane Block for Postoperative Pain Management in Gynaecological Cancer Surgery
The aim of this study was to compare the efficacy of transversus abdominis plane block for postoperative analgesia in gynaecological cancer surgery.
- Trial name
- NCT07077863
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Duygu Akyol
Gynecologic Disease, Gynecologic Cancer
Resilience and Quality of Life in Patients With Gynaecological Carcinomas and Chronic Gynaecological Diseases
The intended pilot project aims at evaluating the feasibility and acceptability of questionnaires about resilience and quality of life in two different patient groups (either with a gynaecological carcinoma ora chronic…
- Trial name
- NCT03916445
- Testing
- Connor Davidson Resilience Scale (CD-RISC 10)
- Where
- Switzerland
- Volunteers
- 132 people
- Sponsor
- University Hospital, Basel, Switzerland
Gynaecological Oncology
Survival Outcomes of Gynecologic Oncology Patients at Assiut University
This retrospective cohort study investigates survival outcomes of gynecological oncology patients treated at Assiut University Hospital between 2022 and 2025, comparing them to international benchmarks and assessing factors…
- Trial name
- NCT07232212
- Volunteers
- 200 people
- Sponsor
- Assiut University
ERAS, Compliance
Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study
ERAS (Enhanced Recovery After Surgery) protocols are step-by-step care plans that help patients recover faster after surgery. They focus on keeping the body's normal functions, lowering stress from surgery, and supporting a…
- Conditions
- ERAS, Compliance, Quality of Life (QOL), Excercise
- Trial name
- Pre_ERAS (NCT07210164)
- Testing
- Ocoxin, Structured self-guided exercise
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Gastrointestinal Cancer, Neuroendocrine Tumours
A Phase II Trial of Ipilimumab and Nivolumab for the Treatment of Rare Cancers
The three tumour streams that will be studied in this protocol are: (i) upper GI malignancies (comprising intra-hepatic/extra-hepatic cholangiocarcinomas,gall bladder cancers and duodenal cancers).); (ii) neuroendocrine tumours…
- Conditions
- Gastrointestinal Cancer, Neuroendocrine Tumours, Malignant Female Reproductive System Neoplasm
- Trial name
- NCT02923934
- Testing
- Ipilimumab, Nivolumab
- Where
- 5 sites in Australia
- Volunteers
- 120 people
- Sponsor
- Olivia Newton-John Cancer Research Institute
Ovarian Tumor, Ovarian Cancer
Prospective RegIstration Of the peRformance of the IoTa ADNEX Model in Dutch gYnaecological Practice
Multicenter prospective cohort study in which patients ≥18 years with an ovarian tumor for which an ultrasound has been performed in accordance with IOTA criteria and the IOTA ADNEX model has been applied are included.
- Trial name
- PRIORITY (NCT06103916)
- Testing
- Observational study. Prospective registration of ultrasound data in patients with ovarian tumors for which an ultrasound in according with the IOTA definitions is performed.
- Where
- Netherlands
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Gynecologic Cancer, Endometrial Cancer
3D Printed Custom Applicators for HDR BT (DISCO)
Intracavitary brachytherapy for gynaecological cancer currently use cylinder-type applicators or custom wax moulds to place a radioactive source in close proximity to the treatment area and provide highly conformal dose…
- Conditions
- Gynecologic Cancer, Endometrial Cancer, Vaginal Cancer, Vulva Cancer
- Trial name
- NCT06432478
- Testing
- 3D-printed custom applicator
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Royal North Shore Hospital
Gynecologic Cancer
Rehabilitation of Women Following Treatment for Gynaecological Cancer; a Randomized, Controlled Study
The purpose of the study is to evaluate and compare the effect of: 1 Educational and counselling in groups, 2) Physical training in group with 3) Control group, on global- and health related quality of life and coping in patients…
- Trial name
- NCT01304745
- Testing
- Physical training in group, Educational and counseling in group
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Haukeland University Hospital
Cervix Neoplasms, Ovarian Neoplasms
Diagnostic Imaging of Lymph Nodes in Gynaecologic Oncology
The purpose of the study is to determine the diagnostic accuracy of a new magnetic resonance imaging (MRI) technique, the diffusion weighted imaging with body background signal suppression (DWIBS) in the detection of lymph node…
- Conditions
- Cervix Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Vulvar Neoplasms
- Trial name
- NCT00288821
- Where
- Netherlands
- Volunteers
- 84 people
- Sponsor
- UMC Utrecht
Ovarian Cancer, Endometrial Cancer
Sexual Health Integration in Treatment of Gynecological Oncology
The goal of this cross-section observational and questionary based study is to learn how geological cancer survivors perceive sexual health support given by health care professionals during diagnosis and treatment process.
- Conditions
- Ovarian Cancer, Endometrial Cancer, Cervical Cancers, Vaginal Cancers
- Trial name
- SHIFT-GO (NCT06958068)
- Where
- Poland
- Volunteers
- 324 people
- Sponsor
- Medical University of Silesia
Gynecologic Cancer
To Explore the Benefits of the MonaLisa Touch® System in Gynaecological Cancer Patients Treated by (Chemo)-RT
The increasing survival rate of gynaecological cancer patients highlights the need to improve their Quality of Life (QoL) after treatment.
- Trial name
- SQUAL (NCT05891470)
- Testing
- MonaLisa Touch device, Vaginal dilatators
- Where
- Belgium
- Volunteers
- 136 people
- Sponsor
- Jules Bordet Institute
Endometrial Cancer, Cervical Cancer
Sexual Rehabilitation Programme After Radiotherapy for Gynaecological Cancer
The aim of this randomized controlled trial is to demonstrate that a nurse-led sexual rehabilitation intervention significantly improves sexual recovery and functioning among gynaecological cancer (GC) patients treated with…
- Conditions
- Endometrial Cancer, Cervical Cancer, Vaginal Cancer, Gynecologic Cancer
- Trial name
- SPARC (NCT03611517)
- Testing
- Sexual rehabilitation programme
- Where
- 8 sites in Netherlands
- Volunteers
- 220 people
- Sponsor
- Leiden University Medical Center
Female Genital Diseases, Ovarian Cancer
Prospective Evaluation of Lymphoedema Among Patients With Gynaecological Cancer
This project will conduct a prospective, longitudinal, observational cohort study to assess the onset and incidence of lymphoedema, as well as investigate factors associated with its development among women newly diagnosed with…
- Conditions
- Female Genital Diseases, Ovarian Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- LEGS (NCT00604994)
- Where
- 6 sites in Australia
- Volunteers
- 761 people
- Sponsor
- Queensland Centre for Gynaecological Cancer
D010051, Ovarian Cancer
Validation of ESGO Quality Indicators in Advanced Ovarian Cancer Surgery
This study, organized by the European Society of Gynaecological Oncology (ESGO), evaluates the clinical impact of adherence to ten ESGO-established quality indicators (QIs) in advanced ovarian cancer surgery.
- Conditions
- D010051, Ovarian Cancer, Advanced-stage Ovarian Cancer, FIGO Stages III and IV
- Trial name
- retroESGO ov1 (NCT07567573)
- Testing
- Preoperative Evaluations, Cytoreductive Surgery, Perioperative Management
- Where
- Belgium
- Volunteers
- 11,383 people
- Sponsor
- European Society of Gynaecological Oncology
Ovarian Neoplasms, Breast Neoplasms
Establishment of a Tumor Bank for Tissue Samples
Establishment of a tumor bank, consisting of tissue samples of tumor patients (benign and malign tumors) and healthy people as controls.
- Conditions
- Ovarian Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Neoplasms of the Female Genitalia
- Trial name
- NCT01789229
- Testing
- Tumor tissue collection, Sampling of ascites and pleural effusion, Collecting urine samples
- Where
- 3 sites in Austria, Belgium and 1 more
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Lymphoedema, Breast Cancer
Spa Therapy for Upper or Lower Limb Lymphoedema
THERMOEDEME is a comparative, controlled, randomized, multicenter and simple blinded (investigator) trial. The aim of this study is to evaluate effects of spa therapy in phlebology with a therapeutic education program in daily…
- Conditions
- Lymphoedema, Breast Cancer, Malignant Disease, Gynaecological Cancer
- Trial name
- THERMOEDEME (NCT03580109)
- Testing
- Immediate spa treatment, Late spa treatment
- Where
- 13 sites in France
- Volunteers
- 160 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Malignant Female Reproductive System Neoplasm, Follow-up
Person-centred Support for Women After Treatment for Gynaecological Cancer
Women treated for gynaecological cancer perceive many difficulties in life on the personal, social, and physical levels. Today they are offered a 3 to 5 year follow-up programme at the hospital where the main purpose is to…
- Conditions
- Malignant Female Reproductive System Neoplasm, Follow-up, Supportive Care, Psychosocial Circumstances
- Trial name
- PESU (NCT01784406)
- Testing
- Autonomy supportive counselling
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet