Clinical trials: Gynaecological Cancers
Gynecologic Cancers
Alveolar Recruitment in Obese Patients in Major Gynaecological Cancer Surgery
In this study, the investigators planned to evaluate the effect of alveolar recruitment strategy primarily on postoperative pulmonary complications in obese patients undergoing lung protective ventilation in major open…
- Trial name
- NCT06619626
- Testing
- alveolar recruitment strategy applied group, group without alveolar recruitment strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Ovarian Neoplasm Epithelial
The Effects of Hemodilution Methods in Patients Undergoing Primary Debulking Gynaecological Surgery
Primary cytoreductive surgery for ovarian cancer is an ideal setting to evaluate endothelial function under ANH and AHH, as the procedure is associated with moderately high blood loss.
- Trial name
- NCT06103214
- Testing
- acute normovolemic hemodilution (ANH), acute hypervolemic hemodilution (AHH)
- Volunteers
- 144 people
- Sponsor
- Zhejiang Cancer Hospital
Surgery, Mobilization
Using Pedometers for the Assessment and Enhancement of Mobility in Gynaecological and Oncological Patients Following Surgery.
This is a prospective cohort study, planned to study the effects of pedometers (digital step counters) on patient mobility following gynecology and gynecology oncology surgeries.
- Conditions
- Surgery, Mobilization, Gynecologic Cancer
- Trial name
- NCT04711421
- Testing
- 4 VIVOFIT-
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Gynecologic Cancers
Attitudes to Gynae Oncology Care Location - GRACEFUL
Gynaecological oncology (cancer) place of care is often based on evolution of services, along historical professional boundaries, rather than user needs or preferences.
- Trial name
- GRACEFUL (NCT06920342)
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- Somerset NHS Foundation Trust
Gynaecological Disease, Vitamin D Deficiency
Association Between Vitamin D and the Risk of Uterine Fibroids
The aim of this randomised clinical trial study is to evaluate whether supplementation with vitamin D could reduce the risk of uterine fibroids in reproductive stage women.
- Conditions
- Gynaecological Disease, Vitamin D Deficiency, Uterine Fibroids
- Trial name
- ABVDATROUF (NCT03586947)
- Testing
- Vitamin D3 400 UNT Oral Capsule
- Where
- China
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Cancer
Effects of Music Intervention Combined With Progressive Muscle Relaxation in Cancer Patients
Study design A 2-arm, assessor-blinded randomised controlled trial will be conducted. The design will follow the Standard Protocol Items Recommendations for Interventional Trials (SPIRIT)
- Trial name
- NCT05262621
- Testing
- progressive muscle relaxation, Listening to relaxing music once/day
- Where
- Vietnam
- Volunteers
- 84 people
- Sponsor
- The Nethersole School of Nursing
Gynecologic Cancers, Postoperative Pain
Postoperative Chronic Pain in Gynaecological Cancer Surgery
The aim of this study was to determine the incidence of postoperative chronic pain in gynaecological cancer surgery and the analgesia methods used for postoperative analgesia.
- Trial name
- NCT07077889
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Gynaecological Cancer, Chemotherapy
Effects of Symptom Management Education With Mobile Application in Gynecological Cancer Patients Receiving Chemotherapy
Gynaecological cancers, which have an important place among the cancers seen both in the world and in our country. Chemotherapy, which is one of the most commonly used and basic methods in cancer treatment, causes many physical…
- Conditions
- Gynaecological Cancer, Chemotherapy, Nursing Care
- Trial name
- NCT06713122
- Testing
- İntervention Group- Group receiving Symptom Management Training with Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Esra Nur Erdoğan
Cervical Cancer
Strategies to Improve the Experience of Gynaecological Screening
The aim is to evaluate different strategies to improve the experience and effect of the first visit for a cervical screening test (CST). 1.
- Trial name
- NCT05131581
- Testing
- Changed clinical context, Extra time allotted, RLP-information
- Where
- Sweden
- Volunteers
- 206 people
- Sponsor
- Uppsala University
Gynaecological Cancers
Vaginal Fluid Derived Biomarkers in the Early Detection and Evolution of Gynaecological Cancers
This study will investigate vaginal secretions in those patients with cancer versus those who are cancer free and compare changes in specific markers that change when a cancer first develops.
- Trial name
- VIOLET (NCT07622953)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Digestive Cancer, Gynaecological Cancer
Surgical Activity During the Covid-19 Pandemic: Results for 112 Patients in a French Tertiary Care Center
Background After the emergence of Covid-19 in China, Hubei Province, the epidemic quickly spread to Europe. France was quickly hit and the Croix-Rousse hospital at the Hospices Civils de Lyon was one of the first French…
- Conditions
- Digestive Cancer, Gynaecological Cancer, Head and Neck Cancer
- Trial name
- SurgiCovid (NCT04379232)
- Testing
- Screening test for covid ( RT PCR and CT Chest)
- Where
- France
- Volunteers
- 112 people
- Sponsor
- Hospices Civils de Lyon
Empowerment, Cervical Cancer, Endometrial Cancer, Follow-up, Nurse-led, PROM
An Individualised and Patient-centred Follow-up Program for Women With Gynaecological Cancer
This randomized controlled trial is testing the hypothesis that an individually focused and need-based nurse led follow-up program supported by electronic Patient Reported Outcome Measures for women with gynecological cancer will…
- Trial name
- NEMO (NCT03838861)
- Testing
- NEMO: NEw MOdel of follow-up
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- University of Southern Denmark
Gynaecological Cancer
Palliation in Gynae-oncology: Patients Expectations and Assessment of Care (PEACE)
The overall aim is to assess the feasibility and acceptability of collecting data on the patients and carers perception of care as well as to prospectively monitor end of life care.
- Trial name
- PEACE (NCT05142150)
- Testing
- Questionaire
- Where
- Norway
- Volunteers
- 73 people
- Sponsor
- Nordic Society of Gynaecological Oncology - Clinical Trials Unit
Gynecological Cancers
Study to Assess the Safety and Effects of Porphysome Nanoparticles for Imaging in Gynaecological Cancers
This is an open-label, first-in-human, dose escalation study evaluating investigational drug PORPHYSOSMES (PS, pegylated porphyrin-lipid conjugate-containing nanoparticle suspension) and 64Cu-PORPHYSOMES (64Cu-PS, pegylated…
- Trial name
- NCT06977126
- Testing
- PORPHYSOMES, 64Cu-PORPHYSOMES
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Postoperative Pain, Postoperative Complications
Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery
The aim of this prospective randomized study was to compare the effectiveness of subcostal transversus abdominis plane block or rectus sheath block applied in addition to posterior transversus abdominis plane block for…
- Conditions
- Postoperative Pain, Postoperative Complications, Analgesia, Regional Anesthesia Morbidity
- Trial name
- NCT06342076
- Testing
- Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block, Patients undergoing rectus sheat block and posterior transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Pelvic Cancer
A Review of Functional and Surgical Outcomes of Gynaecological Reconstruction in the Context of Pelvic Exenteration
Patients with locally advanced pelvic malignancy undergo radical procedures, necessitate organ reconstruction. Little is known about the preferred methods of gynaecological organ reconstruction in the context of pelvic…
- Trial name
- NCT05074069
- Testing
- Gynaecological reconstruction
- Where
- Ireland
- Volunteers
- 334 people
- Sponsor
- St Vincent's University Hospital, Ireland
Gynaecologic Cancer
More Representative Vaginal Temperature Measurements With a Hyperthermia Pelotte During Hyperthermia Treatments for Gynaecological Cancer.
The goal of this comparative, cross over single centre study is to to determine whether the average measured vaginal temperature during hyperthermia treatment is (clinically) significant different with the use of a pelotte than…
- Trial name
- ORIENTATE (NCT07235540)
- Testing
- Pelotte
- Where
- Netherlands
- Volunteers
- 27 people
- Sponsor
- Dr. G.H. (Henrike) Westerveld
Prebiotics, Microbiota
Mixture of Prebiotics on Intestinal Microbiota of Patients Receiving Abdominal Radiotherapy.
Abdominal and pelvic radiotherapy (RT) reduces the renewal capacity of the epithelium. Rectal biopsies obtained from patients receiving pelvic RT have revealed atrophy of surface epithelium, acute cryptitis, crypt abscesses…
- Conditions
- Prebiotics, Microbiota, Radiation Therapy Complication, Endometrial Neoplasms
- Trial name
- NCT01549782
- Testing
- Inulin and Fructo-oligosaccharide, Maltodextrine
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Cervical Cancer, Gynecologic Cancer
Spatially Fractionated Radiation Treatment for Gynaecological Cancers
This is a prospective study to evaluate in-field disease control, survival and late toxicity in patients with cervical cancer or pelvic recurrence treated with spatially fractionated RT.
- Conditions
- Cervical Cancer, Gynecologic Cancer, Recurrent Cancer
- Trial name
- NCT06644846
- Testing
- Spatially fractionated radiation therapy
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Tata Memorial Hospital
Epithelial Ovarian Cancer, Peritoneal Cancer
LCC-CARIS-01: Molecular Profiling in Gynaecological Cancer
This is a pilot feasibility study assessing the use of a commercial molecular profiling service in the UK's National Health Service (NHS).
- Conditions
- Epithelial Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer, Gynaecological Malignancy
- Trial name
- NCT02668913
- Testing
- Diagnostic analysis
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- Geoff Hall