Clinical trials: Gynecological Surgeries
Postoperative Nausea and Vomiting (PONV)
Dexamethasone for Prevention of Postoperative Vomiting After Laparoscopic Gynecologic Surgery
Postoperative nausea and vomiting (PONV) are common and distressing complications following laparoscopic gynecologic surgery. This randomized controlled trial evaluated whether a single preoperative intravenous dose of…
- Trial name
- PONV-DEX-GYN (NCT07421817)
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Rawalpindi Medical College
Anesthesia
TEAS to Improve Outcome During Emergence From General Anesthesia After Robotic Surgery
This study is to observe whether transcutaneous electrical stimulation at specific acupoints could improve the quality of emergence in patients undergoing robotic laparoscopic gynecologic surgery.
- Trial name
- TIGER (NCT02323958)
- Testing
- acupoint stimulation, non-acupoint stimulation, electrode attached
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Air Force Military Medical University, China
Postoperative Nausea and Vomiting
The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
This study was designed to compare the effects of gabapentin and ramosetron on PONV in patients undergoing laparoscopic gynecologic surgery.
- Trial name
- PONV (NCT02617121)
- Testing
- Gabapentin, Ramosetron, Gabapentin and Ramosetron
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Pain, Postoperative, Pain, Acute
Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine
The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT04858711
- Testing
- ketamine-lidocaine-dexmedetomidine, fentanyl
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Vaginal Fistula
Non-inferiority of Short-term Catheterization Following Fistula Repair Surgery
This facility-based, multi-center randomized controlled trial (RCT) will test the non-inferiority of short-term (7 day) urethral catheterization compared to longer-term (14 day) urethral catheterization in terms of predicting…
- Trial name
- NCT01428830
- Testing
- 7-day catheterization following fistula repair surgery, 14 day catheterization
- Where
- 8 sites in Democratic Republic of the Congo, Ethiopia and 6 more
- Volunteers
- 524 people
- Sponsor
- EngenderHealth
Monitoring, Intraoperative
Effects of IV Administration of Ketamine on the Analgesia Nociception Index (ANI) Measured With the PhysioDoloris
This study evaluates effects of the analgesic ketamine on ANI measurements (Anti Nociceptive Index)
- Trial name
- NCT01717521
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Gum Chewing
Effect of Chewing Gum on Gastrointestinal Function Recovery After Surgery of Gynecological Cancer Patients
A total patients undergoing abdominal complete surgical staging for various gynecological cancers were randomized into a gum-chewing group or a control group.
- Trial name
- NCT03669107
- Testing
- Gum
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Gynecologic, ERAS
ERAS and Postoperative Recovery in Gynecologic Patients: A QoR-15 Study
The Quality of Recovery-15 (QoR-15) questionnaire is a widely used Patient-Reported Outcome Measure (PROM) for evaluating postoperative recovery, including pain, physical function, and emotional well-being.
- Trial name
- NCT06878079
- Volunteers
- 130 people
- Sponsor
- National Taiwan University Hospital
Optic Nerve Sheath Diameter
Anesthesia on Optic Nerve Sheath Diameter
Different amounts of anesthetic gas can be used in the obstetric gynecological surgery operations to be performed with open method.
- Trial name
- NCT04407715
- Testing
- The Effect Of Minimal and High Flow Anesthesia on Optic Nerve Sheath Diamater
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Uterine Myoma, Ovarian Cyst
The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing Gynecologic Laparoscopic Surgery With Trendelenburg Position
In patients undergoing gynecologic laparoscopic surgery with trendelenburg position, the disturbance of pulmonary gas exchange frequently occurs due to high intra-abdominal pressure.
- Conditions
- Uterine Myoma, Ovarian Cyst, Laparoscopic Gynecologic Surgery
- Trial name
- NCT01379313
- Testing
- conventional I:E ratio, 1:1 ratio, 2:1 group
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Shivering
Prophylactic Mirtazapine or Dexamethasone for Post-spinal Anesthesia Shivering
This study was conducted to evaluate the effect of a prophylactic dose of oral mirtazapine on shivering compared with prophylactic intravenous infusion (IVI) dexamethasone in patients undergoing gynecological surgeries under…
- Trial name
- NCT03675555
- Testing
- Mirtazapine, Dexamethasone phosphate
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Ain Shams University
Intraocular Pressure, Oncology
Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients
Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in…
- Trial name
- NCT04281017
- Testing
- TIVA, Balanced anesthesia
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Analgesia
Comparison of Standard Epidural and Dural Puncture Epidural Analgesia in Open Gynecological Surgery Techniques
The aim of this study is to compare the effectiveness of standard epidural and dural puncture epidural analgesia techniques used under NOL guidance.
- Trial name
- NCT05408052
- Testing
- Dural Puncture Epidural (DPE), Standart Epidural
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Endometriosis (Diagnosis)
Observational Study on the Use of Ultrasound to Recognize Superficial Endometriosis in a Specific Area of the Pelvis (the Uterosacral Ligaments)
An observational, prospective, multicenter study conducted on patients of childbearing age undergoing laparoscopic surgery for early-stage benign or malignant gynecological disease.
- Trial name
- LUS (NCT07427849)
- Testing
- laparoscopic surgery for gynecological pathology
- Where
- 4 sites in Italy
- Volunteers
- 64 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Influence of Perioperative Fluid Regime on Intraocular Pressure During Laparoscopic Gynecologic Surgery
Influence of Perioperative Fluid Management on Intraocular Pressure During Hynecologic Laparoscopic Pelvic Surgery
The aim of this study was to quantify the Intraocular Pressure (IOP) changes in patients undergoing laparoscopic hysterectomy at different time points and body positions throughout the procedure, and to explore the influence of…
- Trial name
- NCT01676064
- Testing
- ringer lactate solution, restrictive fluid regime
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ziv Hospital
Length of Stay, Postoperative Complications
Fast-track Surgery After Gynecological Oncology Surgery
Fast-track surgery (FTS) pathway, also known as enhanced recovery after surgery (ERAS), FTS is a multidisciplinary approach aiming to accelerate recovery, reduce complications, minimize hospital stay without an increased…
- Conditions
- Length of Stay, Postoperative Complications, CRP
- Trial name
- NCT02687412
- Testing
- pre-operative assessment, counseling and education, Preoperative nutritional drink up to 4 h prior to surgery, bowel preparation
- Where
- China
- Volunteers
- 107 people
- Sponsor
- Ling Cui
Gynecologic Disease
To Evaluate Anti-adhesive Effect and Safety of a Mixed Solid of Poloxamer, Gelatin and Chitosan(Mediclore®)
The purpose of this study is to evaluate the efficacy and safety of Mediclore®, as an antiadhesive barrier, which is made of Poloxamer, Gelatin and Chitosan.
- Trial name
- antiadhesion (NCT02957500)
- Testing
- Mediclore® (adhesion barrier)
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- CGBio Inc.
Gynecologic Disease, Postoperative Ileus
Postoperative Chewing Gum and Gynecological Laparoscopic Surgery
The authors aimed to evaluate the effects of postoperative gum chewing on laparoscopic gynecological surgery, gastrointestinal function-intestinal mobility and early postoperative recovery.
- Conditions
- Gynecologic Disease, Postoperative Ileus, Paralytic Ileus
- Trial name
- NCT03884244
- Testing
- chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Postoperative Complications
Effect of Low-Dose Dexamethasone on the Incidence of Hyperglycemia Following Surgery
The question of a possible hyperglycemic effect from single-dose dexamethasone is an important issue for clinicians managing patients in the intraoperative and postoperative periods.
- Trial name
- NCT01545700
- Testing
- Control-saline, Dexamethasone 4 mg, Dexamethasone 8 mg
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Endeavor Health