Clinical trials: Gynecology
Flumazenil Adverse Reaction, Ambulatory Surgery
Reversal of Remimazolam by a Single Dose of Flumazenil
Remimazolam, a brand-new sedative which has benzodiazepine property. It is an ultra-short acting sedative and regarded as a proper drug for procedural sedation.
- Conditions
- Flumazenil Adverse Reaction, Ambulatory Surgery, Postoperative Nausea, Remimazolam
- Trial name
- NCT05382806
- Testing
- Flumazenil
- Where
- South Korea
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Pelvic Pain, Depression
Psychosocial Treatment for Women With Depression and Pain
Patients with depression and pain have poorer outcomes in response to depression treatments than depressed patients without pain.
- Trial name
- NCT00895999
- Testing
- Interpersonal Therapy for Pain (IPT-P), Enhanced Support and Connection to Counseling
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Breast Neoplasms, Uterine Cervical Neoplasms
Early Detection of Cancers in Low Resource Countries
The purpose of this study is to implement a community-based combined program for early detection of breast, cervical, ovarian and endometrial cancer in low-resource countries delivered through a free standing or a mobile Well…
- Conditions
- Breast Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms
- Trial name
- NCT01178736
- Testing
- Breast Cancer Screening and Diagnosis, Cervical Cancer Screening and Diagnosis, Ovarian Cancer Screening and Diagnosis
- Where
- 3 sites in Brazil, Cambodia and 1 more
- Volunteers
- 36,000 people, healthy volunteers welcome
- Sponsor
- Woman's Cancer Foundation
ERAS
Web-Based Education on ERAS Protocols Applied in Gynecological and Obstetric Surgery
In this research, a pretest-posttest single group quasi-experimental model will be used. The study will be conducted to determine the effect of web-based training given to midwives and nurses on their level of knowledge regarding…
- Trial name
- NCT06066190
- Testing
- Web-Based Training on ERAS Protocols Applied in Gynecological and Obstetric Surgery
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Optic Nerve Sheath Diameter
Anesthesia on Optic Nerve Sheath Diameter
Different amounts of anesthetic gas can be used in the obstetric gynecological surgery operations to be performed with open method.
- Trial name
- NCT04407715
- Testing
- The Effect Of Minimal and High Flow Anesthesia on Optic Nerve Sheath Diamater
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Whey Protein, Postoperative Outcomes
Effect of Whey Protein Supplementation on Postoperative Outcomes After Gynecological Cancer Surgery
Major surgeries including gynecological cancer surgery can make surgical stress that leads to increased burden of postoperative complications, delayed length of hospital stay and increased mortality rate.
- Conditions
- Whey Protein, Postoperative Outcomes, Gynecological Cancer Surgery
- Trial name
- NCT06035510
- Testing
- whey protein supplement
- Where
- Thailand
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Neonate, Maternal Transmission
Phase 3 Maternal Safety & Immunogenicity Trial of MVA-BN® in DRC
This Phase 3 open-label study aims to assess the safety and immune response of the MVA-BN mpox vaccine when administered subcutaneously to pregnant and postpartum women in the Democratic Republic of the Congo (DRC), a population…
- Conditions
- Neonate, Maternal Transmission, Mpox, Vaccination
- Trial name
- PregInPoxVac (NCT06844500)
- Testing
- MVA-BN standard regimen, MVA-BN standard regimen (Administered as PEP)
- Where
- Democratic Republic of the Congo
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- Jean-Pierre Van geertruyden
Postoperative Pain
Administration of Pre-Operative Gabapentin to Patients Undergoing Laparoscopy
The purpose of this study is to prospectively determine the influence of immediate pre-operative gabapentin administration on acute postoperative pain.
- Trial name
- Gabapentin (NCT02359110)
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Anovulation, Amenorrhea
Effects of Gynecological Age on LH Sensitivity to Energy Availability
The purpose of this experiment is to investigate whether the dependence of luteinizing hormone pulsatility on energy availability declines during adolescence.
- Conditions
- Anovulation, Amenorrhea, Infertility, Starvation
- Trial name
- NCT00260286
- Testing
- Energy availability
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ohio University
Intubation
Postoperative Analgesic Requirements for the ProSeal Laryngeal Mask Airway Versus the Tracheal Tube in Females Undergoing Gynecological Laparoscopic Surgery
The ProSeal laryngeal mask airway is a relatively new airway device with a modified cuff to increase the seal and a drain tube to provide a channel for regurgitated fluid, prevention of gastric insufflation and insertion of a…
- Trial name
- NCT00402870
- Testing
- ProSeal LMA, ProSeal LMA, Tracheal Tube
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Problems With Access to Health Care
Quality Assurance of Obstetrics and Gynecology Department
This work aimed to prepare the obstetrics and gynecology department for high education and health care accreditation.
- Trial name
- NCT02101502
- Testing
- Questioner
- Where
- Egypt
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Female Dry Genital Mucosa
Dermal and Gynecological Acceptability (Irritability and Sensitization in the Genital Mucosa) of an Investigational Product and Evaluation of Moisture Efficacy by TEWL and Perceived Efficacy.
To evaluate the safety of an investigational product through the verification of signs of irritability and sensitization of the genital mucosa, as well as the instrumental moisturizing efficacy by TEWL and barrier integrity…
- Trial name
- DERM GYN ACCEP (NCT03007615)
- Testing
- Intimate Lubricant Gel
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Kley Hertz S/A
Laparoscopic Gynecological Surgery
Effects of Standard and Modified Z-Trendelenburg Positions on Cerebral Oxygenation and Optic Nerve Sheath Diameter
The purpose of this study is to compare the effects of the standard Trendelenburg position and the modified Z-Trendelenburg position on cerebral oxygenation and optic nerve sheath diameter (ONSD) in patients undergoing…
- Trial name
- MOD-TREND (NCT07632287)
- Testing
- Standard Trendelenburg Position, Modified Z-Trendelenburg Position
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Prevention
Intravenous Versus Intraperitoneal Instillation of Ondansetron for Decreasing Incidence of Nausea and Vomiting After Laparoscopic Gynecological Surgeries.
Study the effect of intraperitoneal instillation vs intravenous ondansetron on PONV added to intraperitoneal bupivacaine for enhanced recovery and to decrease incidence of PONV after laparoscopic surgeries.
- Trial name
- NCT05317611
- Testing
- Intraperitoneal instillation of ondansetron and bupivacaine, Intravenous ondansetron and intraperitoneal instillation of bupivacaine, Intraperitoneal instillation of bupivacaine
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Anesthetic Regional Techniques for Vaginal Surgeries
Regional Anesthesia
Both techniques are efficacious for sacral anesthesia during vaginal surgeries. Dural puncture epidural technique allows partial confirmation of epidural catheter placement.
- Trial name
- NCT04933500
- Testing
- Whitacre spinal needle
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Pregnancy
Clinical Data Collection for Obstetric Ultrasound Algorithms
The goal of this clinical trial is to Collect ultrasound data from pregnant and non-pregnant individuals presenting to multiple study sites.
- Trial name
- MOBUS (NCT06742229)
- Testing
- Research Ultrasound scan
- Where
- 3 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Caption Health, Inc.
Gynecologic Operations, Anti-Mullerian Hormone
The Impact of Gynecological Surgery on Ovarian Function in Women of Reproductive Age: Postoperative Changes of Serum Anti-Müllerian Hormone (AMH)
Besides the removal of lesions, the purpose of surgeries has been extended to the improvement of quality of life after procedures. Minimally invasive surgeries enabled women to experience less pain, less hospital days.
- Conditions
- Gynecologic Operations, Anti-Mullerian Hormone, Ovarian Reserve
- Trial name
- NCT00928044
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Search MeSH
Investigating the Correlation Between Pre-Treatment Imaging-Derived Body Composition, Chemotherapy Dose Adjustment, and Treatment Efficacy in Gynecological Cancer Patients "
The dosage of paclitaxel, an adjuvant chemotherapy agent for endometrial and ovarian cancer, is typically calculated based on the patient's body surface area (BSA).
- Trial name
- NCT07144618
- Testing
- National Cheng Kung University Abdominal Muscle Group Medical Imaging Analysis Software
- Where
- Taiwan
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Vaginal Hysterectomy
Effect of Validated Skills Simulation With the Miya Model
Simulation training with the Miya Model will improve Operating Room performance of Vaginal Hysterectomy (VH) in novice surgeons and this phase of the study is designed to test that.
- Trial name
- NCT05418764
- Testing
- Miyamodel Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Gynecologic Cancer, Hereditary Cancer Syndrome
Chatbot to Maximize Hereditary Cancer Genetic Risk Assessment
In this study, the investigators aim to compare a mobile health platform, known as a 'chatbot,' that leverages artificial intelligence and natural language processing to scale communication, to 'usual care' that patients would…
- Trial name
- NCT05562778
- Testing
- Chatbot
- Where
- 4 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University