Clinical trials: Gynecomastia
Gynecomastia
Comparison of Endoscopic and Open Surgery for Gynecomastia
The goal of this observational study is to compare the clinical outcomes, safety, and patient satisfaction of endoscopic versus conventional open surgical techniques in adult male patients undergoing surgery for gynecomastia.
- Trial name
- NCT07653152
- Testing
- Endoscopic Nipple-Areola Complex-Preserving Mastectomy, Conventional Open Nipple-Areola Complex-Preserving Mastectomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Antalya City Hospital
Prostate Cancer (Adenocarcinoma)
Determining INdividual Preferences for Gynecomastia avOidance (DINGO) - Stage 1
This study aims to explore the perceptions of men with prostate cancer (PCa) and high-risk biochemical recurrence (BCR) regarding the risk of breast-related side effects, including gynaecomastia, from treatment.
- Trial name
- DINGO (NCT07552922)
- Testing
- Semi-structured Interview
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- St Vincent's Hospital, Sydney
Gynecomastia
Periareolar Excision vs Pull-Through in Gynecomastia
This prospective randomized controlled trial compares periareolar excision and pull-through techniques in 64 patients with Simon Grade I-IIb gynecomastia. Patients were randomized 1:1 and followed for 6 months.
- Trial name
- NCT07485309
- Testing
- Periareolar Excision, Pull-Through Technique
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Kafrelsheikh University
Gynecomastia
To Evaluate the Effectiveness and Safety of Single-port Robotic-assisted Subcutaneous Gland Resection in Males
The new technology of robotic surgery system, as an emerging technology, has shown certain application prospects in breast surgery.
- Trial name
- NCT07353411
- Testing
- Single-port Robotic-assisted Subcutaneous Gland Resection in males
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Gynecomastia
A Clinical Effectiveness Study of Total Laparoscopic Subcutaneous Gland Resection Combined With Nipple-Areola Complex Lift in the Management of Moderate to Severe Gynecomastia in Males
This study aims to evaluate and compare the treatment outcomes of total laparoscopic subcutaneous gland resection combined with nipple-areola complex (NAC) lift surgery against those of isolated laparoscopic surgery in the…
- Trial name
- NCT07314086
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Gynecomastia
Modularities of Management of Severe Grades of Gynecomastia.
Gynecomastia is defined as a benign enlargement of the mammary glands, commonly diffused among men. The prevalence of gynecomastia ranges from 38 to 64 percent in the male population.
- Trial name
- NCT07257445
- Testing
- Group A: circumerolar skin excision, Group B: elliptical skin excision with pedicled flap +_ lateral roll excision., Group C: elliptical skin excision with free nipple areola complex +_ lateral roll excision.
- Volunteers
- 45 people
- Sponsor
- Assiut University
Serratus Anterior Plane Block
Serratus Anterior Plane Block, Ultrasound vs Anatomical Landmark Guided.
This prospective, double-blinded randomized controlled trial aims to compare the efficacy of the serratus anterior plane block (SAPB) ultrasound guided versus anatomical landmark guided for gynecomastia surgery.
- Trial name
- NCT06340880
- Testing
- Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Surgical Managment of Gynecomastia
Evaluation of Feasibility and Aesthetic Outcomes of Benelli Technique for Nipple Sparing Mastectomy in Surgical Treatment of Grade 3 and 4 Gynecomastia
Gynecomastia is the benign proliferation of male breast tissue caused by an increase in the estrogen/androgen activity ratio. It manifests itself physiologically (adolescence, puberty, and old age) as well as pathologically…
- Trial name
- NCT06473064
- Testing
- Benelli technique for nipple sparing mastectomy in surgical treatment of grade 3 and 4 gynecomastia
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Gynecomastia
Renuvion APR System When Used as an Adjunct Procedure In Gynecomastia Surgery
This is a prospective, multi-center, single-blinded, randomized study of up to 10 study subjects undergoing bilateral gynecomastia surgery with Renuvion APR System used as an adjunct procedure on one side.
- Trial name
- NCT05093049
- Testing
- Renuvion APR System, Gynecomastia Correction Surgery
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Apyx Medical
Breast Cancer, Gynecomastia
Effect of Suture Material on Postoperative Nipple Areolar Complex Widening
This will be a single-blinded study where participants are blinded to the suture type but the surgeon will draw a random, unmarked envelope containing the designated suture type at the start of the surgery.
- Conditions
- Breast Cancer, Gynecomastia, Transgenderism, Breast Asymmetry
- Trial name
- NCT06070324
- Testing
- Breast surgery, Suturing of surgical incision
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Gynecomastia, Surgical Incision
Modified Benelli Procedure For Subcutaneous Mastectomy
The study included 150 patients with gynecomastia (Grade II and III) for the period between January 2010 and January 2016 who attended private hospitals and Al- Kindy Teaching Hospital.
- Trial name
- NCT04063722
- Testing
- modified Benelli procedure
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Al-Kindy College of Medicine
Gynecomastia, Thoracic Interfascial Plane Block
Thoracic Interfascial Plane Block Versus Thoracic Paravertebral Block in Gynecomastia Surgery
The growing increase in the number of gynecomastia surgeries has resulted in an increased need for anesthetic techniques with improved pain reduction, safety, and fewer complications.
- Conditions
- Gynecomastia, Thoracic Interfascial Plane Block, Thoracic Paravertebral Block, Anesthesia
- Trial name
- NCT04425447
- Testing
- Tumescent local anesthesia, Thoracic paravertebral block, Thoracic interfascial plane block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Gynecomastia, Delayed Wound Healing
Nitropaste in Breast Reduction
The purpose of this study is evaluate the effect of Nitroglycerin paste on wound healing and scarring. Previous research has shown that Nitroglycerin paste can improve the blood flow to a wound, which may be associated with…
- Trial name
- NCT04321967
- Testing
- Nitroglycerin Paste, Dermabond
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gynecomastia, Endocrine System Diseases
Skincare Products and Environmental Health
The purpose of this study is to explore the potential for an association between the development of prepubertal gynecomastia and history exposure to lavender essential oil, tea tree essential oil, and other essential oils.
- Trial name
- NCT04836364
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Nutraceuticals Research Institute
Gynecomastia
Treatment of Mild and Moderate Cases of Gynaecomastia
This study aims to compare liposuction and periareolar surgical excision in mild and moderate cases of gynecomastia as regard cosmosis, complications, patient satisfaction, operation time, and hospital stay.
- Trial name
- NCT04966078
- Testing
- liposuction, surgical excision
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Gynecomastia, Adolescent
Ultrasound Guided Modified Pectoral Plane Block Versus Erector Spinae Plane Block During GA in Gynecomastia Surgery
Pain of breast surgery is due to chest wall scar and arm in some cases like carcinoma or due to nerve injury.It is neuropathic or nociceptive pain.Its severity is depending on the extent of surgery and the radiotherapy if needed.
- Trial name
- NCT04221074
- Testing
- PECS II versus ESP
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Gynecomastia, Male Breast Enlargement
UltraShape Device for Non-Invasive Fat Reduction in the Male Breast (Pseudogynecomastia)
Male volunteers who suffer from Pseudogynecomastia and seek noninvasive breast fat reduction will be enrolled into two arms to receive three biweekly UltraShape treatments.
- Trial name
- NCT02711605
- Testing
- UltraShape focused ultrasound device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Syneron Medical
Gynecomastia
Post-massive Weight Loss Chest Contouring: Inferior Pedicle Technique in Pseudo-gynecomastia Correction
The massive weight loss leads an important excess of skin on thoracic level giving the aspect of a feminine breast with a relatively important ptose.
- Trial name
- NCT03319862
- Testing
- Inferior pédicule gynaecomastia
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Gynecomastia
Targeted Fat Reduction of Pseudogynecomastia in the Male Breast Using the ZELTIQ Coolsculpting System
Protocol is intended for the clinical evaluation of fat reduction in male breasts (pseudogynecomastia) using the ZELTIQ Coolsculpting System.
- Trial name
- NCT01791660
- Testing
- Zeltiq Coolsculpting System
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dermatology, Laser & Vein Specialists of the Carolinas
Gynecomastia
Open Label Arimidex in Gynecomastia
The purpose of this study is to evaluate the safety, effectiveness, pharmacokinetics and pharmacodynamics of anastrozole (ARIMIDEX™) in the treatment of boys with gynecomastia.
- Trial name
- NCT00241436
- Testing
- Anastrozole (ARIMIDEX™)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- AstraZeneca