Clinical trials: H Pylori Eradication
Helicobacter Pylori Infection
The Role of Probiotics in the Eradication of Helicobacter Pylori
All patients will receive quadruple eradication therapy for 10 days with Omerazole 20mg x2, Amoxicilin 1g x2, Clarithromycin 500mg x2 and Metronidazole 500mg x2. The patients will be randomised into two groups.
- Trial name
- NCT04178187
- Testing
- Caps Lactolevure
- Where
- 5 sites in Greece
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
GASTRITIS
Levofloxacin-Doxycycline for Helicobacter Pylori Eradication in Saudi Arabia
Helicobacter pylori (H. pylori) eradication is achieved in 60-80% with first-line therapy. Different second-line therapeutic options are available.
- Trial name
- NCT02884713
- Testing
- Levofloxacin, Doxycycline, Esomeprazole
- Volunteers
- 55 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Oral Helicobacter Pylori
The Effective Treatment of Oral Helicobacter Pylori With the Success Rate of Gastric Eradication
1. Gastric eradication has no effective on oral H. pylori infection. 2. Treatment of oral infection increase success rate of eradication on stomach infection.
- Trial name
- NCT01863823
- Testing
- Amoxicillin and Tetracyclines, Mouth washing
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Ameritek USA
Helicobacter Infections
Dual Therapy With High Doses of Ilaprazole and Amoxicillin for Helicobacter Pylori Infection
This study assessed eradication rate of dual therapy with high doses of Ilaprazole 40mg BID and Amoxicillin 750mg QID for 14 days on Helicobacter pylori infection.
- Trial name
- NCT02401477
- Testing
- Ilaprazole + Amoxicillin
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Il-Yang Pharm. Co., Ltd.
HELICOBACTER PYLORI INFECTIONS
Lignin in Treatment of Helicobacter Pylori Infection
The goal of this clinical trial is to learn if drug hydrolyzed lignin works to treat H pylori infection in adults. It will also learn about the safety of drug lignin n the sitting of H pylori infection, and if it halts the side…
- Trial name
- NCT07246681
- Testing
- Hydrolyzed Lignin
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Zagazig University
Helicobacter Pylori Infection, Compliance, Patient
Comparison of Bismuth Containing Quadruple Therapy and Based Tailored Therapy for H. Pylori Infection
As the antibiotic resistance increases, the eradication rate of triple therapy is decreasing. Recent guideline recommend the use of bismuth-containing quadruple therapy in areas where clarithromycin resistance is greater than…
- Conditions
- Helicobacter Pylori Infection, Compliance, Patient, Drug Resistance, Antibiotics
- Trial name
- NCT03361267
- Testing
- Helicobacter pylori PCR test, CLO test
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Inha University Hospital
Helicobacter Pylori Infection
Study of Levofloxacin-based Concomitant Therapy for H. Pylori Eradication in Diabetic Patients
The study aims to evaluate H. pylori eradication rate in diabetic patients by using novel 10-day levofloxacin-based concomitant therapy compared with conventional 10-day sequential therapy.
- Trial name
- NCT02466919
- Testing
- Pantoprazole, Amoxicillin, Metronidazole
- Volunteers
- 114 people
- Sponsor
- Chung-Tai Wu
Helicobacter Pylori Infection
Efficacy of Vonoprazan in Eradication of Resistant Strain of Helicobacter Pylori
The goal of this Randomized controlled trial is to assessment Efficacy of Vonoprazan versus Proton Pump Inhibitors in Combination with Antibiotics as a triple Therapy for Eradication of Clarithromycin Resistant Strain of…
- Trial name
- NCT06414707
- Testing
- Vonoprazan, Amoxicillin and Levofloxacin, Pantoprazole 40mg, Amoxicillin and Levofloxacin
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Ain Shams University
Helicobacter Pylori Infection
The Effects of a Synbiotic Addition on Eradication Therapy of Helicobacter Pylori Infection in Children
The aim of the study is to evaluate the effects of the synbiotic Bifidobacterium animalis ssp. lactis B94 plus inulin addition to the standard triple therapy on Helicobacter pylori infection eradication rates in children.
- Trial name
- NCT03165253
- Testing
- Bifidobacterium Animalis Oral Product, Amoxicillin Oral Tablet, Clarithromycin Oral Tablet
- Volunteers
- 69 people
- Sponsor
- Bulent Ecevit University
Helicobacter Pylori Infection
Molecular Detection of Antibiotic Resistance and H Pylori Eradication
H pylori eradication failure with recommended triple therapy is mainly related to antibiotic resistance. However,IN VITRO culture of H pylori is uneasy and is not performed in routine practice.
- Trial name
- HELICOSTIC (NCT01168063)
- Testing
- Molecular detection of antibiotic resistance, standard triple therapy (PPI, amoxicillin, clarithromycin, metronidazole)
- Where
- France
- Volunteers
- 1,386 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastric Cancer, Helicobacter Pylori Infection
Helicobacter Pylori Eradication With Different Bismuth Quadruple Therapies
This study aims to compare efficacy and safety of bismuth-containing quadruple therapy（with rabeprazole amoxicillin clarithromycin）of different kinds of bismuth（Bismuth potassium citrate, pectin bismuth capsules, pectin bismuth…
- Conditions
- Gastric Cancer, Helicobacter Pylori Infection, Bismuth
- Trial name
- NCT04209933
- Testing
- Bismuth potassium citrate containing quadruple therapy, Colloidal pectin bismuth capsules containing quadruple therapy, Colloidal pectin bismuth particles A quadruple therapy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori Infection
Comparison of Two Rescue Therapies for Helicobacter Pylori Infection
From the profiles of antibiotic susceptibility data following eradication therapy, tetracycline, amoxicillin and levofloxacin are all good candidates of antibiotics used in the rescue treatment.
- Trial name
- NCT02547012
- Testing
- esomeprazole+amox+levo+tetra, esomeprazole+amox+levo
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Helicobacter Pylori Eradication
Serum Pepsinogen After H. Pylori Eradication
Helicobacter pylori has been recognized as a major pathogen in gastric carcinogenesis. Current guidelines recommend the H. pylori "test-and-treat" strategy for the purpose of primary and secondary gastric cancer prevention.
- Trial name
- NCT03924375
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Soonchunhyang University Hospital
Helicobacter Pylori Infection
Tegoprazan-containing Sequential for H. Pylori
As H. pylori eradication, the investigators prepared a randomized controlled clinical trial whether tegoprazan-containing 10-day sequential treatment was effective compared to conventional PPI-containing 10-day sequential…
- Trial name
- NCT06382493
- Testing
- Tegoprazan-containing sequential H. pylori eradication therapy, Esomeprazole-containing sequential H. pylori eradication therapy
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Helicobacter Pylori Infection
A Clinical Trial on the Efficacy of Gastric Probiotics in the Treatment of Helicobacter Pylori Infection
The purpose of this study is to assess the safety and efficacy of Lactobacillus plantarum, Bacillus coagulans and Lactobacillus plantarum + Bacillus coagulans for eradication of Helicobacter Pylori, as well as the efficacy of…
- Trial name
- NCT05483660
- Testing
- Lactobacillus plantarum, Bacillus coagulans, Lactobacillus plantarum + Bacillus coagulans
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
HELICOBACTER PYLORI INFECTIONS, Metabolic Syndrome
Eradication of Helicobacter Pylori Improves Metabolic Syndrome Through Modulation of Gut Microbiota.
The Role of Gut Microbiota in the Mechanism of Helicobacter pylori Eradication-Induced Amelioration of Metabolic Syndrome-Related Parameters Study Sponsor: Nanjing First Hospital Principal Investigator: Dr.
- Trial name
- NCT07306988
- Testing
- Vonoprazan-Amoxicillin Dual Therapy, Vonoprazan-Amoxicillin with Bifidobacterium tetravaccae, Vonoprazan-Amoxicillin with Berberine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Helicobacter Pylori Infection
Metronidazole- Versus Tinidazole-Based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication
This randomized, open-label clinical trial will compare two bismuth-containing quadruple therapies for the first-line treatment of Helicobacter pylori infection. Adults aged 18 years or older with confirmed H.
- Trial name
- NCT07746934
- Testing
- Metronidazole, Tinidazole 500mg, tetracyline
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Helicobacter Pylori Infection
Tailored Therapy for Helicobacter Pylori in Children
This study is designed to compare the eradication rates，safety and compliance of tailored therapy to those of standard triple therapy in children with H. pylori infection.
- Trial name
- NCT02635191
- Testing
- Tailored Group, Standard group
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Children's Hospital
H Pylori Infection
Genotypic Resistance Guided Therapy for Refractory H. Pylori Infection
The inviestigators aimed to compare the efficacy of genotypic resistance guided versus susceptibility testing guided therapy in the third line treatment for refractory H. pylori infection.
- Trial name
- NCT03555526
- Testing
- Esomeprazole 40mg, Amoxicillin, metronidazole
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Helicobacter Pylori Infection
Comparison of Helicobacter Pylori Eradication Effect Before and After Training of Gastroenterologists
The researchers recruited gastroenterologists. Physician subjects recruited Helicobacter pylori-positive patients before and after receiving standardized training on Helicobacter pylori eradication.
- Trial name
- NCT05065138
- Testing
- Standardized training on Helicobacter pylori eradication treatment
- Where
- China
- Volunteers
- 1,025 people, healthy volunteers welcome
- Sponsor
- Shandong University