Clinical trials: H Pylori Infection
Helicobacter Pylori
Association of Oral Helicobacter Pylori Infection With Gastric Helicobacter Pylori Infection
The aim of this study was to investigate the association between oral Helicobacter pylori infection and gastric Helicobacter pylori infection.
- Trial name
- NCT05790512
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori Infection
Eradication of Helicobacter Pylori With a Lactobacillus Reuteri Strain Plus Proton Pump Inhibitor
Meta-analyses involving >4000 subjects with probiotics added to antimicrobial Helicobacter pylori eradication therapy in populations with antibiotic resistance have reported a mean increase in eradication rate of 12.2%.
- Trial name
- NCT03404440
- Testing
- L.Reuteri
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- University of Bari
Helicobacter Infection
Keverprazan-Minocycline Dual Therapy of Different Durations Versus Bismuth Quadruple Therapy for Helicobacter Pylori Eradication.
This study aims to compare the efficacy and safety of keverprazan-minocycline dual therapy versus bismuth-based quadruple therapy for Helicobacter pylori eradication, focusing on eradication rates, patient adherence, and the…
- Trial name
- NCT07904429
- Testing
- Minocycline, Keverprazan, Amoxicillin
- Where
- China
- Volunteers
- 612 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
H Pylori Infection, Atherogenic Plasma Index
H. Pylori Infection and AIP Levels
Helicobacter pylori is a common bacterial infection of the stomach that can cause ulcers and other digestive problems. Recent studies suggest that this infection may also affect metabolism and blood fats (lipids), which are…
- Trial name
- HP-AIP (NCT07306377)
- Testing
- urea breath test
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tanta University
Helicobacter Pylori Infection
Comparison Between Ten Days Sequential Treatment and Traditional Three Combined Treatment of Helicobacter Pylori
The purpose of this study is to compare the eradication efficacy of 10-day triple therapy with 10-day sequential therapy with tetracycline or metronidazole.
- Trial name
- NCT01573975
- Testing
- 5RA-5RCM, 5RA-5RCT, 10RCA
- Where
- Taiwan
- Volunteers
- 345 people
- Sponsor
- Buddhist Tzu Chi General Hospital
HELICOBACTER PYLORI INFECTIONS
Optimizing H. Pylori Eradication Regimen Under Intensified Acid Suppression
Background: Helicobacter pylori (H. pylori) infection affects approximately 50% of the global population and is closely associated with chronic gastritis, peptic ulcer disease, and gastric cancer. Eradication of H.
- Trial name
- NCT07750938
- Testing
- Keverprazan Hydrochloride 20 mg TID, Minocycline 100 mg (10-Day Regimen), Keverprazan Hydrochloride 20 mg BID
- Volunteers
- 316 people
- Sponsor
- Qilu Hospital of Shandong University
Helicobacter Pylori Infection
Comparing the Efficacy of Reverse Hybrid Therapy and Bismuth Quadruple Therapy
Reverse hybrid therapy achieves a higher eradication rate than bismuth quadruple therapy remained unanswered.
- Trial name
- NCT02547038
- Testing
- pantoprazole+bismuth+tetra+metro, (panto+amox+clar+metr)+(panto+amox)
- Where
- Taiwan
- Volunteers
- 352 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Helicobacter Pylori Infection, Renal Transplant Infection
Helicobacter Pylori Infection in Renal Transplant Patients
Upper gastrointestinal (GI) symptoms are frequent in organ transplant recipients. Peptic ulcers and related pathologies such as gastritis and duodenitis are known to occur with increased frequency (20-60%) and severity in renal…
- Trial name
- NCT03310255
- Testing
- H pylori Faecal Antigen
- Volunteers
- 86 people
- Sponsor
- Assiut University
Acute Coronary Syndrome
Helicobacter Pylori Infection in Acute Myocardial Infarction Patients
This study aims to investigate the association between H.Pylori and ACS .
- Trial name
- NCT05788055
- Testing
- Stool Analysis
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Helicobacter Pylori Infection
14-day Double Therapy Versus Bismuth Quadruple Therapy in First-line Treatment of Helicobacter Pylori Infection
The researchers collected untreated H. pylori positive patients from outpatient clinics. Subjects were randomized to 14 days of dual therapy with Tegoprazan or 14 days of quadruple therapy with bismuth for eradication.
- Trial name
- NCT05438550
- Testing
- 14-day high-dose Tegoprazan Dual Therapy (HDDT)
- Where
- China
- Volunteers
- 258 people
- Sponsor
- Shandong University
Migraine in Children
Association of Helicobacter Pylori Infection and Migraine
The study aims to assess the relation between migraine and H pylori infection in children and adolescent.
- Trial name
- NCT06558578
- Testing
- Helicobacter pylori antigen in stool
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Helicobacter Pylori Infection
The Impact of Antibiotics MIC Value on the Efficacy of Treatment Regimens for Helicobacter Pylori Infection.
Clarithromycin (CLA)、amoxicillin (AMO)、metronidazole (MET)、levofloxacin (LEV) and tetracycline (TET) are commonly used antibiotics for Helicobacter pylori (Hp) therapy.
- Trial name
- NCT03583476
- Testing
- Proton pump inhibitor,clarithromycin,amoxicillin or metronidazole
- Where
- Taiwan
- Volunteers
- 1,821 people
- Sponsor
- National Taiwan University Hospital
H.Pylori Infection, H.Pylori Gastrointestinal Disease
Concomitant Versus Hybrid Regimen for H. Pylori Eradication
10 day concomitant versus 14 day hybrid regimen as first line H. pylori eradication treatment in a high clarithromycin resistance area. A multicenter, randomized, equivalence trial.
- Conditions
- H.Pylori Infection, H.Pylori Gastrointestinal Disease, H. Pylori Associated Phlegmonous Gastritis
- Trial name
- NCT03592069
- Testing
- 10 day concomitant regimen, 14 day hybrid regimen
- Where
- Greece
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Alexandra Hospital, Athens, Greece
H.Pylori Infection
Comparison of Twice- and Four-times-daily Amoxicillin Administration in 2-week Tegoprazan-based H. Pylori Eradication
Gastric acid depressant play a major role in an H. pylori eradication therapy by (1) increasing the intragastric pH, which improves antibiotic stability and bioavailability; (2) increasing the intragastric pH to 6 or more, which…
- Trial name
- NCT06431737
- Testing
- Amoxicillin
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Soonchunhyang University Hospital
HELICOBACTER PYLORI INFECTIONS
Efficacy of a 14-Day Bismuth-Containing Quadruple Therapy Guided by Drug Susceptibility Testing in Patients with Extremely Refractory Helicobacter Pylori Infection: an Exploratory Study
Helicobacter pylori (H. pylori) infection, a prevalent global infectious disease, is a significant contributor to gastric cancer and other morbidities, imposing a substantial disease burden.
- Trial name
- NCT06731023
- Testing
- Bismuth, Vonoprazan, Amoxicillin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xiuli Zuo
Helicobacter Pylori Infection
Study of Nitazoxanide (NTZ) for Helicobacter Pylori in Children
Study of Nitazoxanide (NTZ) based therapeutic regimens for Helicobacter pylori in children
- Trial name
- NCT04415983
- Testing
- Nitazoxanide, Clarithromycin, Metronidazole
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Helicobacter Pylori Infection
Comparing the Efficacy of Reverse Hybrid Therapy and Concomitant Therapy
Reverse hybrid therapy achieves a higher eradication rate than concomitant therapy remains unanswered.
- Trial name
- NCT02646332
- Testing
- (dexlan+amox+clar+metr)+(dexlan+amox), dexlan+clarith+amox+metro
- Where
- Taiwan
- Volunteers
- 248 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Helicobacter Pylori Infection, Chronic Gastritis
Study on The Efficacy and Safety of Berberine-containing Triple Therapy in Helicobacter Pylori First-Line Eradication
The purpose of this study is to assess the efficacy and safety of berberine, amoxicillin and vonoprazan containing triple therapy in Helicobacter Pylori first-line eradication.
- Trial name
- NCT05014334
- Testing
- Berberine, Vonoprazan, Amoxicillin
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Helicobacter Pylori Infection
Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori Infection
Non-bismuth quadruple therapies have been proposed as potential strategies in improving the efficacy of first-line treatments. The non-bismuth quadruple therapy in its concomitant variant consists of proton pump inhibitor…
- Trial name
- NCT04621487
- Testing
- Amoxicillin, Metronidazole, Clarithromycin
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Helicobacter Pylori Infection
LOAD VS Levofloxacine Concomitant
Comparison Efficacy of two weeks Therapy with Doxycycline,levofloxacine,Tinadizole Versus Levofloxacine,Tinadizole,Amocillin on Eradication of Helicobacter Pylori in Syrian population.
- Trial name
- NCT04626193
- Testing
- Doxycycline, Levofloxacin 500mg
- Where
- Syria
- Volunteers
- 80 people
- Sponsor
- Damascus Hospital