Clinical trials: H Pylori Infection
Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
POCone-UBiT-IR300 Pediatric Comparison Study
The purpose of this study is to compare between the POCone® to the UBiT®-IR300 in measuring 13CO2/12CO2 ratio in breath samples when used together with the BreathTek® UBT (urea breath test) Kit and the pUHR-CA web-based software…
- Trial name
- NCT01623154
- Testing
- Pranactin citric solution
- Where
- 3 sites in United States
- Volunteers
- 99 people
- Sponsor
- Otsuka America Pharmaceutical
Helicobacter Infections
Endofaster Test for Helicobacter Pylori Detection in Patients on Proton Pump Inhibitor Therapy
H. pylori infection is the most important causative agent of gastritis, and subsequent atrophic gastritis. The endoscopic diagnosis of H. pylori infection relies on urease tests such as the Clo test.
- Trial name
- NCT02126722
- Testing
- Gastroscopy, EndoFaster test, Clo test
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Niso Biomed S.R.L.
Helicobacter Pylori Infection
A Phase 3 Study to Evaluate the Efficacy and Safety of Triple Therapy With CJ-12420 in H. Pylori Positive Patients
The current study is designed to demonstrate the non-inferiority of CJ-12420-based triple therapy (CJ-12420, amoxicillin and clarithromycin) versus lansoprazole-based triple therapy (lansoprazole, amoxicillin and clarithromycin)…
- Trial name
- NCT03317223
- Testing
- CJ-12420/Clarithromycin/Amoxicillin
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- HK inno.N Corporation
Helicobacter Pylori Infection
Oral H. Pylori Prevalence in Intellectually & Developmentally Disabled Adults
The purpose of this study is to determine if the bacteria that cause gastric infections can be found in the mouths of intellectually and developmentally disabled persons.
- Trial name
- NCT00841490
- Where
- 2 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Helicobacter Pylori Infection
Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection
To compare the efficacy of Helicobacter pylori (HP) eradication with vonoprazan dual and triple therapy regimens versus lansoprazole triple therapy regimen in participants with HP infection, excluding participants who had a…
- Trial name
- NCT04167670
- Testing
- Vonoprazan, Amoxicillin, Clarithromycin
- Where
- 153 sites in United States, Bulgaria and 4 more
- Volunteers
- 1,046 people
- Sponsor
- Phathom Pharmaceuticals, Inc.
Helicobacter Pylori Infection
Efficacy of Acetylcysteine-containing Triple Therapy in the First Line of Helicobacter Pylori Infection
Helicobacter pylori infection has been shown to be associated with the development of gastric cancer and peptic ulcer diseases. Eradication of H. pylori infection could reduce the occurence or recurrence of these diseases.
- Trial name
- NCT02249546
- Testing
- N-acetylcysteine + PPI-amoxicillin-clarithromycin, PPI-amoxicillin-clarithromycin
- Where
- 2 sites in Taiwan
- Volunteers
- 654 people
- Sponsor
- National Taiwan University Hospital
Helicobacter-associated Gastritis
Detection of Helicobacter Pylori Infection by High Resolution Endoscopy
Although endoscopic findings of H. pylori have been reported in the literature, there is still some debate over whether H. pylori-related gastritis can be diagnosed via endoscopic features alone.
- Trial name
- NCT01434992
- Where
- South Korea
- Volunteers
- 585 people
- Sponsor
- Kyunghee University Medical Center
Dyspepsia
Effect of Triple Versus Quadruple Therapy for Treating Helicobacter Pylori Infection
The Goal of this this clinical trial is to assess and compare the eradication rate of triple and quadruple therapy during treating helicobacter pylori infection among patients presented with dyspepsia.
- Trial name
- NCT07010744
- Testing
- Triple drug regimen, Quadruple therapy
- Where
- Bangladesh
- Volunteers
- 66 people
- Sponsor
- Akil Al Islam
Helicobacter Pylori Infection
Intragastric pH and Bismuth Effect for H. Pylori Eradication
Gastric cancer is one of the leading causes of cancer-related deaths worldwide. In Taiwan, there are around 3800 fresh cases annually, with about 5% of total cancers cases.
- Trial name
- NCT02894892
- Testing
- (A)Bismuth, (B)Bismuth, (C)Bismuth
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- National Taiwan University Hospital
Acute Bacterial Infections, Acute Viral Infections
300 Antibody Diagnostic Test Kit
For the development of a Point of Care IVD test kit for acute phase disease detection against a variety of bacterial and viral infections.
- Trial name
- Antibody 300 (NCT01646411)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Plasma Source
Acute Coronary Syndrome, Helicobacter Pylori Infection
The Effect of Dual Eradication Therapy vs PPI on Gastrointestinal Bleeding in ACS Patients
Patients with acute coronary syndrome (ACS) after Percutaneous Coronary Intervention (PCI) require routine treatment with dual antiplatelet (DAPT) treatment, but with the high risk of bleeding, gastrointestinal bleeding is the…
- Trial name
- NCT04728516
- Testing
- Vonoprazan-based dual eradication therapy for two weeks, amoxicillin, Pantoprazole
- Where
- 42 sites in China
- Volunteers
- 2,600 people
- Sponsor
- Qilu Hospital of Shandong University
Immune Thrombocytopenic Purpura, Helicobacter Pylori Infection
Helicobacter Pylori Treatment in Immune Thrombocytopenic Purpura (ITP) Patients
The purpose of this study is to determine whether eradication of Helicobacter pylori infection is effective in the improvement of platelet counts in children and adolescents with chronic ITP.
- Trial name
- NCT01730352
- Testing
- H. pylori triple therapy
- Where
- 4 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of São Paulo
Helicobacter Pylori Infection
Efficacy of High-dose Dual Therapy vs Bismuth-containing Quadruple Therapy for First-line Treatment of Hp Infection
Up to now, there is few randomized, large scale study prospectively and simultaneously comparing the efficacy, adverse effects and patient adherence of high-dose dual therapy (HDDT) and bismuth-containing quadruple therapy (BQT)…
- Trial name
- NCT02483715
- Testing
- High-dose dual therapy (rabeprazole, amoxicillin), Bismuth-containing quadruple therapy (rabeprazole, tripotassium dicitrate bismuthate, metronidazole, tetracycline)
- Where
- Taiwan
- Volunteers
- 589 people
- Sponsor
- National Taiwan University Hospital
Helicobacter Pylori Infection
Tailored Therapy for Helicobacter Pylori Treatment in Patients With Penicillin Allergy
Increasing drug resistance presents a significant challenge to the efficacies of common empiric eradication regimens for Helicobacter pylori treatment in the mainland of China.
- Trial name
- NCT03708848
- Testing
- Esomeprazole, Bismuth Potassium Citrate, Clarithromycin
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Helicobacter Pylori Infection
Study on the Effect of Fecal Microbiota Transplantation on Eradication of Refractory Helicobacter Pylori Infection
To determine whether regulating the gut microbiota can contribute to the eradication of refractory H. pylori infection.
- Trial name
- NCT07704255
- Testing
- transanal fecal bacteria transplant
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Sichuan Provincial People's Hospital
Bowel Dysfunction, Helicobacter Pylori Infection
The Clinical Evaluation of Probiotics Product in Patients With Various Functional Bowel Disorders and Helicobacter Pylori Infection
People nowadays tend to have irregular diet and routine due to the stress at work. This condition may cause intestinal microflora imbalance, and in the long term may lead to constipation, diarrhea, gastroenteritis, gastric ulcer…
- Trial name
- NCT04319991
- Testing
- Probiotics product
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Fooyin University
Helicobacter Pylori Infection
Comparing Different Regimens for Eradication of Helicobacter Pylori in Kuwait
Eradication of H. pylori reduces morbidity in patients with chronic gastritis and can prevent gastric cancer. We aimed to evaluate the efficacy of clarithromycin-based triple therapy and non-bismuth based quadruple therapy for…
- Trial name
- NCT04617613
- Testing
- Omeprazole, Amoxicillin, Metronidazole and Clarithromycin, Omeprazole, Amoxicillin and Clarithromycin
- Volunteers
- 603 people
- Sponsor
- Al-Azhar University
Helicobacter Pylori Infection
Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication: A Randomized Clinical Trial of 10 and 14 Days
The researchers collect treatment-naive H.pylori-positive patients from the outpatient clinic. The subjects were randomized to receive a 10-day or 14-day course of quadruple eradication therapy.
- Trial name
- NCT04901117
- Testing
- Amoxicillin, Clarithromycin, Tetracycline
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection
The Role of Probiotics in the Eradication of Helicobacter Pylori
All patients will receive quadruple eradication therapy for 10 days with Omerazole 20mg x2, Amoxicilin 1g x2, Clarithromycin 500mg x2 and Metronidazole 500mg x2. The patients will be randomised into two groups.
- Trial name
- NCT04178187
- Testing
- Caps Lactolevure
- Where
- 5 sites in Greece
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Helicobacter Pylori Infection, Gastritis
Comparison Between High-dose Amoxicillin Dual Therapy and Pylera Quadruple Therapy in the Treatment of Helicobacter Pylori Infection
Helicobacter pylori is a pathogenic bacteria transmitted from individual to individual, being scientifically recognized as an agent who causes persistent inflammatory activity on the gastric mucosa.
- Conditions
- Helicobacter Pylori Infection, Gastritis, Gastric Cancer
- Trial name
- NCT05100446
- Testing
- Amoxicillin - high dose dual therapy, Pylera, Esomeprazole 40mg
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE