Clinical trials: H.Pylori Infection
H. Pylori Gastrointestinal Disease, H.Pylori Infection
CURE-H. Pylori: A Trial on the Combination of Anti-Ulcerants and Levofloxacin-Based Therapy for Helicobacter Pylori Eradication
This study, titled CURE-H. Pylori, is a three-arm, parallel-group, open-label, randomized controlled trial designed to evaluate the effectiveness of Dexlansoprazole, Lansoprazole, and Vonoprazan in combination with Levofloxacin…
- Conditions
- H. Pylori Gastrointestinal Disease, H.Pylori Infection, H.Pylori Eradication Rate
- Trial name
- CURE-H Pylori (NCT07344506)
- Testing
- Arm 1: Dexlansoprazole + Levofloxacin-Based Triple Therapy, Arm 2: Lansoprazole + Levofloxacin-Based Triple Therapy, Arm 3: Vonoprazan + Levofloxacin-Based Triple Therapy
- Where
- Pakistan
- Volunteers
- 942 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
H. Pylori Infection
Efficacy of TAK-438, Amoxicillin and Clarithromycin in the First Line Eradication of H. Pylori
The purpose of this study is to confirm the efficacy of triple therapy with TAK-438, Amoxicillin and Clarithromycin, twice daily (BID) by demonstrating its non-inferiority to triple therapy with Lansoprazole, Amoxicillin and…
- Trial name
- NCT01505127
- Testing
- TAK-438, Lansoprazole, Amoxicillin
- Where
- 35 sites in Japan
- Volunteers
- 650 people
- Sponsor
- Takeda
H.Pylori Infection
RUT vs. Molecular Testing for H. Pylori
The rapid urease test (RUT) is frequently performed for diagnosis of Helicobacter pylori infection in clinical practice. The RUT is a simple and inexpensive method that utilizes a commercial kit containing urea and a pH indicator…
- Trial name
- NCT06684860
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Soonchunhyang University Hospital
Helicobacter Pylori Infection
Effect of Propolis on Patients Infected With H. Pylori
This research aims to contribute to the literature by researching the effect of propolis as an add-on treatment and nutritional education on patients with H pylori and the alleviation of gastrointestinal symptoms.In order to…
- Trial name
- NCT05259007
- Testing
- propolis solved in lactic acid solvent, Amoxicillin-Clarithromycin-Lansoprazole, IV saline 0.9%
- Volunteers
- 96 people
- Sponsor
- Fatma Zehra Arvas
Suspicion of Being Infected With H.Pylori
Show Equivalence of the Modified BreathID Compared to Currently Approved BreathID in H.Pylori Detection
The purpose of this study is to confirm equivalence of a new generation breath analyzer (Modified BreathID) in its ability to detect H. pylori compared to the currently approved BreathID® System.
- Trial name
- NCT01650831
- Testing
- Modified BreathID
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Meridian Bioscience, Inc.
Gastric Cancer
Pilot Study of Stomach Cancer Early Detection and Prevention With Endoscopy
Screening esophagogastroduodenoscopy (EGD )provides three distinct opportunities to decrease gastric cancer (GC) morbidity and mortality.
- Trial name
- NCT05566899
- Testing
- esophagogastroduodenoscopy (EGD)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
H.Pylori Gastrointestinal Disease, H Pylori Infection
Argentinean Registry on the Management of Helicobacter Pylori Infection
Helicobacter pylori (H pylori) is the main cause of chronic gastritis and peptic ulcer disease. In addition, is the main risk factor for gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma.
- Trial name
- ArgReg-Hp (NCT06579365)
- Where
- Argentina
- Volunteers
- 5,000 people
- Sponsor
- University of Buenos Aires
H.Pylori Infection
Tegoprazan and Amoxicillin Dual Therapy
Dual therapy for Helicobacter pylori refers to a treatment regimen that combines two agents: a potent acid suppressor (such as a proton pump inhibitor [PPI] or a potassium-competitive acid blocker [PCAB]) and the antibiotic…
- Trial name
- NCT06950489
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Soonchunhyang University Hospital
Helicobacter Pylori Infection
Lactoferrin in Helicobacter Pylori Eradication Either With Standard Triple Therapy or Sequential Therapy
The investigators aim at evaluating the efficacy of bovine lactoferrin addition to H. Pylori eradication regimens. 400 randomly distributed participants will be assigned to one of four treatment regimens of H.
- Trial name
- NCT04445948
- Testing
- Esomeprazole 40 milligrams Oral Tablet, Amoxicillin 1000 milligrams tablets, Clarithromycin 500 milligrams Tablets
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Alexandria University
Helicobacter Pylori Infection, Acne Vulgaris
Prevalence of H.Pylori in Patients With Acne Vulgaris Acne Vulgaris
The objective of the study is to investigate prevalence of H.Pylori infection among acne vulgaris patients.
- Trial name
- NCT03411733
- Testing
- Blood and stool samples collection
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cholelithiasis
Gallstones and Concomitant Gastric Helicobacter Pylori Infection
In this study, the presence of H.Pylori in the gallbladder mucosa of patients with symptomatic gallstones undergoing cholecystectomy was investigated.
- Trial name
- NCT01810081
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Marmara University
Dyspepsia, H. Pylori Infection
Supplementation With L. Reuteri in H. Pylori Infected Adults
To determine whether simultaneous use of L. reuteri ProGastria and proton pump inhibitors can eradicate H. pylori in humans in the absence of antibiotics.
- Trial name
- NCT01449500
- Testing
- L. reuteri
- Where
- Slovakia
- Volunteers
- 56 people
- Sponsor
- Lama Medical Care s.r.o.
H.Pylori Infection
Comparative Anti Helicobacter Pylori Efficacy Assessment of Unani Formulation and Quintuple Regimen
Helicobacter pylori (H. pylori) is a bacterium its infection is regarded the most common medical condition associated with gastritis1 more over peptic ulcer disease2, gastric adenocarcinoma3 and lymphoma.4control of H pylori…
- Trial name
- NCT03837210
- Testing
- Pylorin
- Volunteers
- 300 people
- Sponsor
- Hamdard University
Persistent Helicobacter Pylori Infection
Effect of Probiotics on Eradication of Persistent H.Pylori Infection
This study aims to investigate the possible safety and efficacy of probiotics (Bifidobacterium Infants, Enterococcus Feacium, and Lactobacillus Acidophilus) on the eradication rate of Helicobacter pylori and the incidence of…
- Trial name
- NCT05674864
- Testing
- Bifidobacterium Infants plus Enterococcus Feacium plus Lactobacillus Acidophilus
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Tanta University
H.Pylori Infection
Frequency of h.Pylori in Children With Dyspeptic Symptoms
The current work aim to: Estimation of prevalence, Estimation of risk factors, Estimation of endoscopic picture of H. pylori infection in children presented with chronic or recurrent dyspeptic symptoms and/or non variceal…
- Trial name
- NCT05951998
- Volunteers
- 100 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
Efficacy of Clarithromycin and Flouroquinolones Based Regimens in H.Pylori Eradication in Covid-19 Era
Era of COVID-19 and the related panic lead to widely spread antibiotics misuse especially for azithromycin. Cross sensitivity between azithromycin and clarithromycin can impact success rates of H.
- Trial name
- NCT05035186
- Testing
- Amoxicillin
- Where
- Egypt
- Volunteers
- 233 people
- Sponsor
- Alexandria University
Helicobacter Pylori Infection
One vs Two Weeks Treatment for H.Pylori Eradication A RANDOMIZED NON-INFERIORITY PLACEBO CONTROLLED TRIAL
1. To assess the efficacy of the duration of Vonoprazan based triple regimen (one versus two weeks), in the eradication of H-pylori among patients attending gastroenterology clinics of Karachi, Pakistan. 2.
- Trial name
- NCT05728424
- Testing
- Vonoprazan, Amoxicillin, Levofloxacin
- Where
- Pakistan
- Volunteers
- 246 people
- Sponsor
- Aga Khan University
H.Pylori Infection
Safety and Efficacy of Triple and Quadruple Regimens as First Line Therapy for Management of Helicobacter Pylori Infection in Egyptians
Our study aimed to investigate the efficacy and safety of hybrid regimen as a first line therapy for H. pylori eradication compared to triple and quadruple regimens in attempt to overcome antibiotic resistance
- Trial name
- NCT06315478
- Testing
- Omeprazole 20 MG Oral Tablet, Amoxicillin 500Mg Tab, Clarithromycin 500Mg Tab
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Helwan University
CYP2C19 Polymorphism, H.Pylori Infection
Effect of the CYP2C19 Polymorphism in Helicobacter Pylori Eradication
Background: Triple therapy efficacy against Helicobacter pylori is low worldwide, thus alternatives must be sought to improve eradication. Aim: To determine CYP2C19 genetic polymorphism effect on H. pylori eradication.
- Conditions
- CYP2C19 Polymorphism, H.Pylori Infection, Therapy
- Trial name
- NCT03650543
- Testing
- amoxicillin clarithromycin omeprazole 1, amoxicillin clarithromycin omeprazole 2
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Javeriana University
Helicobacter Pylori Infection, Susceptibility to
Helicobacter Pylori Infection Among Women With Recurrent Abortion of Unknown Cause
Helicobacter pylori (H. pylori) infection affects approximately one half of the world population and it is more prevalent in developing countries. This microorganism colonizes the stomach.
- Trial name
- NCT07293169
- Testing
- H pylori eradication
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University