Clinical trials: HAART-treated
Tuberculosis
Tuberculosis Recurrence Upon Treatment With Highly Active Antiretroviral Therapy
This is a cohort observational study investigating the rate of tuberculosis (TB) recurrence in adult patients who have completed TB therapy for Pulmonary TB (PTB) and are on highly active antiretroviral therapy (HAART).The…
- Trial name
- TRuTH (NCT01539005)
- Where
- South Africa
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
HIV Infection
Residual Replication of HIV-1 in the Gut Associated Lymphoid Tissue (GALT) of Patients on Highly Active Antiretroviral Therapy (HAART): the ANRS EP 44 Study
HIV-1 cannot be eradicated from infected individuals by current antiretroviral regimens. Cellular reservoirs and tissue sanctuary sites allow latent HIV-1 persistence and ongoing low-level virus replication.
- Trial name
- EP 44 (NCT01038401)
- Testing
- GI endoscopy and GALT biopsies, A sample of venous blood will also be collected
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Infection, Osteopenia
Effect of HIV Infection and Highly Active Antiretroviral Treatment (HAART) on Bone Homeostasis
Advances in HAART have been a huge success story in the management of HIV infection. However, serious metabolic complications including osteoporosis and bone fractures are increasingly been seen with HAART, and the responsible…
- Conditions
- HIV Infection, Osteopenia, Osteoporosis
- Trial name
- OPG-2 (NCT01020045)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Infections
Adherence and Risk Behaviour in Patients With HIV Infection Receiving Antiretroviral Therapy
Study Hypothesis: Do certain risk behaviours impact/predict levels of HIV antiretroviral adherence? Objectives: To assess risk behavior in HIV-positive individuals receiving highly active antiretroviral therapy.(HAART) To assess…
- Trial name
- ARB (NCT00511056)
- Where
- Thailand
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
HIV Infections
Durability of Adherence in Self-Management of HIV
Adherence to highly active antiretroviral therapy (HAART) is critical to successful treatment of HIV. This study tested an intervention that helps people infected with HIV take all their medications when and how they were…
- Trial name
- DASH (NCT00991302)
- Testing
- CAP-IT
- Where
- 2 sites in United States, Peru
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Medication Adherence
Effects of a Phone Call Intervention to Promote HAART Adherence
The adherence rate (95%) to HAART in the intervention group which receives a phone call will be higher than that(75%)of control group which does not receive a phone call.
- Trial name
- EPCIPHA (NCT01395771)
- Testing
- Phone call intervention, no phone call intervention
- Where
- 4 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Baoshan Prefecture Center for Disease Control and Prevention
HIV Lipodystrophy
Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome
The purpose of this study is to determine whether patients with HIV lipodystrophy (fat wasting) benefit from taking the combination of two drugs, one insulin sensitizer (either metformin or pioglitazone, both diabetes drugs) and…
- Trial name
- NCT00362440
- Testing
- Leptin, Pioglitazone or metformin
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
HIV Infection
Statin Adjunct Therapy Among ART-treated Adults in Sub-Saharan Africa: Atorvastatin and Rosuvastatin Equivalence Trial
This study will determine whether 36 months of daily atorvastatin or rosuvastatin have equivalent effects in reduction of immune activation, inflammation and immune aging, when given as adjunct therapy among patients receiving…
- Trial name
- STAR (NCT03037372)
- Testing
- ART, Atorvastatin, ART, Rosuvastatin, ART, No statin
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Makerere University
HIV Infections, AIDS
Lactate Metabolism Study in HIV Infected Persons
Lactic acidosis is a potentially life-threatening disease associated with the treatment of chronic HIV infection. Although acidosis is rare, hyperlactatemia is common and may have long term consequences yet to be recognized.
- Conditions
- HIV Infections, AIDS, Lactic Acidosis, Lipodystrophy
- Trial name
- NCT00202228
- Testing
- cofactor supplementation (thiamine, riboflavin, L-carnitine)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen's University
HIV Infections
Phase I/II, Open-Label Trial of Three Monoclonal Antibodies
Monoclonal antibody infusions will prevent rebound of viremia in well-suppressed HAART-treated individuals who began therapy during acute and early HIV-1 infection.
- Trial name
- NCT00219986
- Testing
- Potent HAART during acute or early HIV-1 infection
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
HIV Infections
An Enhanced Adherence Support Programme for Highly Active Antiretroviral Therapy (HAART)
In southern Africa, TB is the most common first AIDS-defining condition. Initiating Antiretroviral therapy (ART) in HIV positive TB patients will lead to the inclusion of the majority of HIV/AIDS patients currently fulfilling the…
- Trial name
- eASP (NCT00408642)
- Testing
- Enhanced adherence support, Standard adherence support
- Where
- South Africa
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Centre for the AIDS Programme of Research in South Africa