Clinical trials: HBP
Sleep Apnea Syndrome
Cardiovascular Consequences of Intermittent Hypoxia in Healthy Subjects
The study is a prospective field evaluation to assess the effects of the chronic Intermittent Hypoxia exposure in 12 healthy humans.
- Trial name
- NCT00746928
- Testing
- Chronic Intermittent Hypoxia
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Portal Hypertension
RCT of Carvedilol Versus Variceal Band Ligation in the Primary Prophylaxis of Oesophageal Variceal Haemorrhage
Aim To compare Carvedilol with variceal band ligation in the prevention of first variceal bleed. End points of trial Primary: Variceal hemorrhage Secondary: Death Study design Randomised controlled clinical trial.
- Trial name
- NCT01070641
- Testing
- Carvedilol, Esophageal variceal band ligation
- Where
- Pakistan
- Volunteers
- 148 people
- Sponsor
- Aga Khan University
Cardiovascular Diseases, Hypertension
U-CHAMP: Urban Cardiovascular Health Assessment and Management Program
High blood pressure, elevated blood glucose and high cholesterol are related to the increased risk of stroke and heart disease. Many studies have shown that this risk can be significantly reduced by lowering blood pressure, blood…
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia, Hyperglycemia
- Trial name
- U-CHAMP (NCT00626041)
- Testing
- participant referral to primary care network physician
- Where
- 2 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Gestational Diabetes, Gestational Hypertension
Preventing Obstetric Complications With Dietary Intervention
The goal of this study is to learn whether access to healthy and fresh food, health coaching, and nutrition support intervention can reduce adverse birth outcomes in pregnant women.
- Conditions
- Gestational Diabetes, Gestational Hypertension, High Risk Pregnancy, Preeclampsia
- Trial name
- PLATE (NCT06320054)
- Testing
- Maternal Health Management Program
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Liver Diseases, Portal Hypertension
Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal
This is an open-label, non-randomized trial that will be conducted at three clinical sites, Thomas Jefferson University (TJU), the Hospital of the University of Pennsylvania (HUP) and University of Bern (UB).
- Trial name
- NCT05470205
- Testing
- SHAPE measurement (Sonazoid ultrasoud contrast agent), SHAPE measurement (Definity ultrasoud contrast agent)
- Where
- 3 sites in United States, Switzerland
- Volunteers
- 660 people
- Sponsor
- Thomas Jefferson University
Open-angle Glaucoma
Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser Trabeculoplasty
Evaluation of intraocular pressure (IOP) lowering effect of two iStent stents versus a SLT procedure in subjects with open-angle glaucoma on one ocular hypotensive medication.
- Trial name
- NCT01444105
- Testing
- iStent, SLT
- Where
- Armenia
- Volunteers
- 80 people
- Sponsor
- Glaukos Corporation
Well-controlled Hypertension
Administration Time-dependent Antihypertensive Effects of Low Dose Aspirin in Well-controlled Hypertensive Patients
The purpose of this study is to evaluate the influence of aspirin on blood pressure in well-controlled hypertensive patients who receive low dose aspirin at different times of the day
- Trial name
- NCT00386529
- Testing
- Aspirin enteric coated pellests 100mg
- Where
- South Korea
- Volunteers
- 191 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension
Titrated Disease Management for Patients With Hypertension
This randomized clinical trial examines whether programs aimed at matching resources to patient hypertension (i.e. high blood pressure) control lead to greater reduction in systolic blood pressure (top number of blood pressure…
- Trial name
- TDM (NCT01390272)
- Testing
- Booster/ low resource, Medium/Level 1 resource intensity, High/Level 2 resource intensity
- Where
- United States
- Volunteers
- 385 people
- Sponsor
- VA Office of Research and Development
Glaucoma Open-Angle
Normal Tension and Chronic Open Angle Glaucoma and Cerebrospinal Fluid Composition
Normal tension glaucoma (NTG) and chronic open angle glaucoma (COAG) occurring progressively with optimal conventional or intraocular pressure reducing surgery are still unsolved problems in ophthalmology.
- Trial name
- NCT00306657
- Testing
- Optic nerve sheath fenestration
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Kantonsspital Aarau
Hypertension, High Blood Pressure
Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients
This project will evaluate the clinical and cost effectiveness of a novel, multidisciplinary approach to identify and treat pre-clinical cardiac dysfunction (PCCD) in asymptomatic hypertensive patients identified in a single…
- Conditions
- Hypertension, High Blood Pressure, Ventricular Hypertrophy, Diastolic Dysfunction
- Trial name
- NCT00689819
- Testing
- Exercise, Weight Loss, Low Sodium Diet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Polycystic Ovary Syndrome
Metformin in Pregnant PCOS Women
To investigate the effect of metformin on pregnancy complications and pregnancy outcome in the II. and III. trimester of pregnancy in women with polycystic ovary syndrome.
- Trial name
- PregMet (NCT00159536)
- Testing
- Metformin
- Where
- 10 sites in Norway
- Volunteers
- 257 people
- Sponsor
- Norwegian University of Science and Technology
Glaucoma
Effect of Kron (Citicoline and Nicotinamide Oral Solution) on Patients With Open-angle Glaucoma
Aim of this study is to investigate the administration effects of the combination of citicoline 40mg/ml and nicotinamide 15mg/ml oral solution (Kron®) on short term improvement in inner retinal function, bioelectrical activity of…
- Trial name
- NCT06333236
- Testing
- Food for Special Medical Purposes: Kron®
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- ASST Santi Paolo e Carlo
Ocular Hypertension
Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension
The purpose of this study is to assess the safety and efficacy of Brimonidine/Timolol Fixed Combination in patients with glaucoma or ocular hypertension
- Trial name
- NCT00332436
- Testing
- brimonidine/timolol fixed combination
- Where
- United States
- Volunteers
- 586 people
- Sponsor
- Allergan
Sickle Cell Disease, Pulmonary Hypertension
Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary Hypertension
The goal of this study is to test the hypothesis that hydroxyurea is effective for the specific treatment of secondary pulmonary hypertension found on screening in children and young adults with sickle cell disease.
- Trial name
- NCT00350844
- Testing
- Hydroxyurea
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Hypertension
A Clinical Study to Compare an Aliskiren Based Hypertensive Regimen With a Ramipril Based One Followed by a Randomized Withdrawal.
To compare the aliskiren regimen versus the ramipril regimen on reduction in Blood Pressure.
- Trial name
- NCT00219063
- Testing
- aliskiren
- Where
- United States
- Volunteers
- 844 people
- Sponsor
- Novartis
Glaucoma, Open Angle Glaucoma
iCare® Home vs Goldmann Applanation Tonometry
Self-tonometry with iCare Home is regularly performed at Sankt Erik's Eye Hospital since a few years back. The purpose of this study was to show that the eye pressure measurements made with iCare® Home by patients / relatives do…
- Conditions
- Glaucoma, Open Angle Glaucoma, Ocular Hypertension, Pseudo Exfoliation Syndrome
- Trial name
- NCT04911387
- Testing
- Intraocular pressure measurments
- Where
- Sweden
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- St. Erik Eye Hospital
Respiratory Muscle Strength
Effects of Training in Pulmonary Hypertension
Pulmonary hypertension (HP) is a progressive pathological condition presents with vascular changes in the lung. Cardiopulmonary changes in PH are considered the main limiting factor, however, it is known that the muscular…
- Trial name
- NCT03186092
- Testing
- respiratory muscle training
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Hypertension and Dyslipidemia
A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-386
A Clinical Trial to evaluate the Pharmacokinetics and Tolerability of CKD-386
- Trial name
- NCT04673864
- Testing
- CKD-386, D012, D326, D337
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension, Hyperlipidemia (E.G., Hypercholesterolemia)
A Study to Evaluate the Pharmacokinetic Interaction and Safety Between BR1018-1 and BR1018-2 in Healthy Adult Subjects
The purpose of this study is to evaluate the pharmacokinetic characteristics and compare the safety and tolerability after repeated separate or combined administrations of BR1018-1 and BR1018-2 in healthy adults.
- Trial name
- NCT05460364
- Testing
- BR1018-1, BR1018-2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Healthy Volunteers
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors…
- Trial name
- NCT04286464
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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