Clinical trials: HDL
Alcohol Consumption, Inflammation
Effect of Alcohol Consumption on Markers of Inflammation
Rationale: High-density lipoprotein (HDL), which is consistently increased after moderate alcohol consumption, is an abundant plasma lipoprotein that is generally thought to be anti-inflammatory in both health and infectious…
- Trial name
- AR23 (NCT00918918)
- Testing
- Alcohol + orange juice, Orange juice
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- TNO
Diet Modification, HDL
Effects of Short-term Diet on HDL Composition and Function
The primary objective of this study is to generate preliminary data on the effects of a short-term diet of either fast food or Mediterranean type diet on HDL and microbiota composition and function in healthy subjects, which…
- Conditions
- Diet Modification, HDL, Inflammation
- Trial name
- NCT03205254
- Testing
- Mediterranean Diet, Fast food diet
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Dyslipidemia
Effect of Saturated Fat on Large Low-density Lipoprotein (LDL) and High-density Lipoprotein (HDL)
The purpose of the study is to test whether increased saturated fat intake results in increased levels of larger LDL and HDL particles in individuals with LDL Pattern B.
- Trial name
- NCT00895141
- Testing
- Saturated Fat Diet
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Dyslipidemia
Study of Trilipix Effects on Lipids and Arteries
Fibrates reduce atherosclerosis and cardiovascular disease events. A major mechanism of this benefit appears to be their ability to raise plasma high density lipoprotein cholesterol (HDL-C), especially in patients with high…
- Trial name
- NCT01025492
- Testing
- Trilipix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Utah
Coronary Artery Disease
Effect of Exercise Training on the Function of HDL-Cholesterol, Endothelial Function and Endothelial Progenitor Cells in Patients With Coronary Artery Disease (HERCET-Study)
Patients with coronary artery disease are characterized by an increased cardiovascular risk and they often have low blood high density lipoprotein (HDL)-cholesterol levels or HDL-cholesterol with modified vasculoprotective…
- Trial name
- HERCET (NCT00457379)
- Testing
- physical exercise
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Lateral Epicondylitis
Metabolic and Inflammatory Indices in Lateral Epicondylitis
This study aims to investigate whether metabolic and inflammatory indices differ between patients with chronic lateral epicondylitis (tennis elbow) and individuals without the condition.
- Trial name
- NCT07876778
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Obesity, Abdominal Obesity
Adiponectin, ICAM-1, VCAM-1 Levels and Metabolic Syndrome in Obese Adolescents
Adipose tissue secreting a number of adipokines which regulate insulin sensitivity, energy metabolism and vascular homeostasis, so the dysfunction of adipose tissue is linked with the incidence of obesity accompanied with insulin…
- Conditions
- Obesity, Abdominal Obesity, Metabolic Syndrome, Hypertension
- Trial name
- ICAM; VCAM (NCT05685017)
- Testing
- Nur Aisiyah Widjaja
- Where
- Indonesia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Lipoprotein (a)
Lipid Screening Study
The purpose of this pilot study is to estimate the prevalence of elevated Lipoprotein (a) in an adult primary care population and to describe the distribution of atherogenic lipid markers within this cohort.
- Trial name
- NCT07579325
- Testing
- Venipuncture
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
HIV Infections, Cardiovascular Disease
Effect of Rosuvastatin on Endothelial Function
Rosuvastatin belongs to a class of medications commonly called "statins" which are medications given for high low density lipoprotein (LDL) 'bad' cholesterol to prevent atherosclerosis (hardening of blood vessels) and lower risk…
- Trial name
- NCT00986999
- Testing
- rosuvastatin
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Metabolic Syndrome, Osteoporosis
Exercise and Flax-Based Nutritional Supplementation for Lowering Cholesterol
The purpose of our study is to use a flaxseed-based nutritional supplement in combination with exercise training (walking) for improving cholesterol levels.
- Trial name
- NCT00204412
- Testing
- Flax lignan, Exercise (walking)
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Fetal Macrosomatia, Lipid Metabolism Disorders
Influence of TyG Index and TG/HDL-C Ratio on Fetal Macrosomia
Metabolic disorders that can occur during pregnancy, in particular disorders of lipid metabolism and insulin resistance, can have a detrimental effect on pregnancy and the fetus.
- Conditions
- Fetal Macrosomatia, Lipid Metabolism Disorders, Hyperlipidemias
- Trial name
- NCT06463990
- Testing
- TyG index
- Where
- Turkey (Türkiye)
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Cholesterol, LDL, Cholesterol, HDL
Impact of Beef's Unique Food Matrix on Human Health
The primary goal of the proposed research is to document changes in plasma lipoprotein fractions, including high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particle sizes and functionality, following the ground…
- Conditions
- Cholesterol, LDL, Cholesterol, HDL, Research Subjects
- Trial name
- NCT04841460
- Testing
- Low-fat ground beef, High-fat ground beef
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Coronary Artery Disease
Impaired HDL and Coronary Artery Disease in Anabolic Androgenic Steroid Users
Anabolic androgenic steroids (AASs) have been associated with coronary artery disease (CAD). The illicit use of these substances also leads to a remarkable decrease in high-density lipoprotein (HDL) plasma concentration, which…
- Trial name
- NCT03450837
- Testing
- Coronary Computed Tomography Angiography, Macrophage cholesterol efflux mediated by HDL
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Cardiovascular Disease, Diabetes
The Effects of Natural Versus Man-Made Trans Fatty Acids on Lipoprotein Profiles: A Pilot Study
The purpose of this study is to test the effects of natural vs. man-made trans fatty acids (trans fats) on blood cholesterol.
- Conditions
- Cardiovascular Disease, Diabetes, Dyslipidemia
- Trial name
- NCT00535886
- Testing
- Man-made Trans FA, Natural Trans FA, Oleic Acid
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Disbiosis, Obesity
Limosilactobacillus Fermentum CRL 1446 - CONICET CASASCO
This research study aims to determine if a probiotic called Limosilactobacillus fermentum CRL 1446 can improve the health of people at risk for cardiovascular disease.
- Conditions
- Disbiosis, Obesity, Overweight (BMI > 25), Hypertension (Without Type 2 Diabetes Mellitus)
- Trial name
- NCT07530575
- Testing
- Limosilactobacillus fermentum 1446 CRL CONICET 2.20E+9 CFU
- Where
- 2 sites in Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PINER Pastor Manfredi Winery
Antioxidant Absorption
Evaluation of Obicetrapib on Antioxidant Levels in Plasma and HDL Particles of Healthy Volunteers
The goal of this clinical trial is to learn if Obicetrapib works to change antioxidant levels in HDL and plasma, as well as retinal tissue.
- Trial name
- VERMEER (NCT06982508)
- Testing
- Obicetrapib 10mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NewAmsterdam Pharma
Coronary Heart Disease
Safety and Efficacy of APL180 in Healthy Volunteers and Patients With Coronary Heart Disease (CHD)
The purpose of this study is to determine: (1) the safety and pharmacokinetics of APL180 administered as a single intravenous infusion in healthy volunteers, and (2) the safety, pharmacokinetics and pharmacodynamics of single and…
- Trial name
- NCT00568594
- Testing
- APL180
- Where
- 11 sites in United States, Belgium and 5 more
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Novartis
Diet, Habits
The Effect of Chia Seeds on HDL Cholesterol
The purpose of this clinical trial is to demonstrate the effect of daily consumption of chia seeds, if any, on HDL cholesterol levels and compare this to the effects of oats on HDL levels in adult populations.
- Trial name
- NCT05734170
- Testing
- Chia Seeds and instant oatmeal breakfast, Cheerio Breakfast, Instant Oatmeal breakfast
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Cardiovascular Diseases, Apolipoproteins
Functional Yogurt Consumption and Its Effects on the Lipid Profile of Healthy Subjects
The purpose of this study was to assess the effect of the daily intake of yogurts enhanced with Sacha Inchi oil and hybrid palm tree oil on human plasma lipids related to cardiovascular risk factors
- Conditions
- Cardiovascular Diseases, Apolipoproteins, Food Preferences, Low-density-lipoprotein-type
- Trial name
- FYOPO (NCT06574711)
- Testing
- Sacha inchi oil yogurt, Hybrid palm oil yogurt, Control yogurt
- Where
- Colombia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Javeriana
Hypertriglyceridemia, Dyslipidemia
Efficacy Study of Diazoxide Choline to Treat Hypertriglyceridemia
Once a day oral administration with DCCR helps lower triglycerides
- Trial name
- NCT01211847
- Testing
- Diazoxide Choline Controlled-Release Tablet
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Essentialis, Inc.