Clinical trials: HEALTHY INDIVIDUALS
Therapeutics
Evaluation of the Balance, Muscular Electric Activity, Proprioception Before and After in the Vibratory Platform
Introduction: Proprioception refers to the information's dynamic, sent to central nervous system by the free nerve endings and mechanoreceptors, about the biomechanics relationship for the joint tissue.
- Trial name
- NCT03846037
- Testing
- Proprioceptive exercise on the vibratory platform, Proprioceptive exercise on the ground (stable surface)
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Paraíba
Healthy Lifestyle
Video-Based Exercise for Individuals With Social Isolation Due to Coronavirus (COVID-19)
In December 2019, new coronavirus pneumonia (COVID-19) broke out in Wuhan (Hubei, China), and it spread rapidly from one city to the whole country in just 30 days, and then worldwide cases began to appear.
- Trial name
- NCT04346953
- Testing
- Video based exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Istinye University
Pharmacokinetics, Epinephrine
Study of Drug Exposure in Systemic Circulation of Primatene Mist by Oral Inhalation, Versus Epinephrine Injection by Intramuscular Injection and ProAir by Oral Inhalation in Healthy Individuals
To assess the drug exposure profile in systemic circulation of Primatene Mist by inhalation, versus Epinephrine by intramuscular injection, and ProAir HFA by inhalation in healthy adults.
- Conditions
- Pharmacokinetics, Epinephrine, Albuterol, Asthma
- Trial name
- NCT04207840
- Testing
- Epinephrine (0.125 mg/inhalation), Epinephrine Injection Auto-Injector (0.3mg/0.3mL), Albuterol Sulfate (0.09 mg/inhalation)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Achilles Tendon Thickness, Plantar Fascia Thickness
The Relationship Between Plantar Fascia and Achilles Tendon Thickness Asymmetry and Spatio-temporal Parameters of Gait
There are studies on loading the foot with an increase in the thickness of the Plantar Fascia and Achilles Tendon. However, no study was found that evaluated the relationship between morphological features such as plantar fascia…
- Conditions
- Achilles Tendon Thickness, Plantar Fascia Thickness, Spatio-temporal Parameteres of Gait
- Trial name
- NCT05976542
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Volunteers
Inspiratory Muscle Endurance of Adults
The aim of this study is to determine the reference value ranges for healthy adults of the incremental threshold load test, which evaluates respiratory muscle endurance.
- Trial name
- NCT05237427
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Choroid Disease, Diabetes Mellitus
Measuring Choroidal Thickness Using Optical Coherence Tomography
To compare the choroidal thickness in eyes of diabetic patients with eyes of age matched controls using optical coherence tomography.
- Trial name
- NCT06272851
- Testing
- optical coherence tomography
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy
Ramelteon for a Nap Prior to a Night Shift
Night shift-workers are often advised to take a prophylactic nap prior to starting the shift in order to improve alertness and performance.
- Trial name
- NCT00595075
- Testing
- Ramelteon
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Healthy Individuals
Effect of Induced Rotator Cuff Muscles Fatigue on Hand Grip Strength in Adults
This observational study aims to investigate the effect of induced rotator cuff muscles fatigue on hand grip strength in adults
- Trial name
- NCT07054853
- Testing
- Induced rotator cuff fatigue by isokinetic biodex
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Noura Karam Abdou Mohammed Ismaiel
Postprandial Blood Glucose, Gut Microbiota
Effect of Fat Quality on Glycemic Regulation and Gut Microbiota After a Short-time Intervention in Healthy Individuals
The overall aim is to investigate effects of saturated versus polyunsaturated fat on glycemic regulation and satiety in a postprandial study with healthy individuals.
- Conditions
- Postprandial Blood Glucose, Gut Microbiota, Satiety
- Trial name
- NCT03658681
- Testing
- Saturated fat 14.9 E%, Polyunsaturated fat 13.6 E%
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Quorum Sensing, Prebiotics
Biological Modulation of Bacterial QSSMs, Innate and Adaptive Immunity by Antibiotics, Probiotics and Prebiotics in Healthy Individuals
It has recently been discovered that bacteria are able to communicate using specialised molecules known as Quorum Sensing Signalling Molecules (QSSMs).
- Conditions
- Quorum Sensing, Prebiotics, Probiotics, Sepsis
- Trial name
- NCT01201577
- Testing
- Bifidobacterium longum BB536, Active hexose correlated compound (AHCC), Bifidobacterium longum BB536 and Active hexose correlated compound (AHCC)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Respiratory Problems
The Effect of Hypermobility Healthy Individuals
Benign Joint Hypermobility Syndrome is a hereditary connective tissue problem characterized by the emergence of multiple musculoskeletal problems in hypermobile individuals without a systemic rheumatologic disease.
- Trial name
- NCT04208022
- Testing
- Respiratory evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Kültür University
Focus of Study: Healthy Individuals
Effectiveness of a Well-being Web-based Intervention
The purpose of this study is to determine whether the intervention Daily Challenge (MeYou Health, LLC), a behavioral intervention delivered online, is effective in improving individuals' well-being.
- Trial name
- NCT01586949
- Testing
- Daily Challenge
- Where
- United States
- Volunteers
- 1,503 people, healthy volunteers welcome
- Sponsor
- MeYou Health, LLC
Pancreatic Cancer
A Case-control Study Comparing Glycaemic Control in Pancreatic Cancer Patients vs Healthy Matched Individuals.
The aim of this study is to continuously monitor blood glucose concentrations for a 7-day period in pancreatic cancer patients whilst undergoing their typical daily routines and to compare this to age matched healthy individuals.
- Trial name
- PanCanCGM (NCT05583890)
- Testing
- Continuous glucose monitors, Activity tracker, Food Diary
- Where
- 2 sites in United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Healthy Aging, Risk Reduction
Validation of the REMINDER Dementia Risk Reduction Program
Until now, neuropsychological interventions aimed to optimize cognitive function and to have functional impact in individuals at risk of AD (MCI patients) were scarce in validity studies.
- Conditions
- Healthy Aging, Risk Reduction, Old Age; Dementia
- Trial name
- REMINDER (NCT05296980)
- Testing
- REMINDER, Brain health Psychoeducation
- Where
- Portugal
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Exercise
Pro-rEsolving and pRo-inflammatory reSPonses to Acute exhaustIve exeRcisE in Healthy Individuals
This is a study of the effects of acute, exhaustive exercise on pro-resolving and pro-inflammatory responses in healthy, trained and untrained adults.
- Trial name
- PERSPIRE (NCT05923125)
- Testing
- Graded-Intensity Treadmill Exercise Protocol
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Mantra Meditation, Mantra Meditation + Body-Oriented Yoga
Meditation Based Lifestyle Modification in Healthy Individuals
MBLM is a holistic therapy for people with mental disorders whose positive effects on patients with depression have already been demonstrated in clinical use and a pilot study.
- Conditions
- Mantra Meditation, Mantra Meditation + Body-Oriented Yoga, Mantra Meditation + Ethical Living, Mantra Meditation + Body-Oriented Yoga + Ethical Living
- Trial name
- MBLM-H (NCT04252976)
- Testing
- Ethical Living, Yoga Exercises, Mantra Meditation
- Where
- Germany
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Diakonie Kliniken Zschadraß
Sarcoid, Cardiovascular Diseases
Evaluation of PET Probe [64]Cu-Macrin in Cardiovascular Disease, Cancer and Sarcoidosis.
To evaluate the safety of [64Cu] Macrin and its whole-body distribution, metabolism, pharmacokinetics, and radiation burden in healthy volunteers.
- Conditions
- Sarcoid, Cardiovascular Diseases, Cancer
- Trial name
- NCT04843891
- Testing
- [64]Cu Macrin
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ralph Weissleder, MD
Eczema, Atopic Dermatitis
Studies of Skin Microbes in Healthy People and in People With Skin Conditions
This study will examine microbes (e.g., bacteria, fungi, viruses) that live on human skin and how microbes contribute to health and disease.
- Trial name
- NCT00605878
- Where
- United States
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Healthy Eating Index, Muscle Strain
Evaluation of the Relationship Between Healthy Eating and Intrinsic Capacity in Elderly Individuals
The aim of this study is to evaluate the relationship between intrinsic capacity and healthy eating in elderly individuals.
- Conditions
- Healthy Eating Index, Muscle Strain, Frailty
- Trial name
- NCT05335343
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Diabetic Polyneuropathy, Healthy Individuals (Controls)
PULP SENSIBILITY AND MASSETER INHIBITORY REFLEX IN DIABETIC POLYNEUROPATHY
Accurate evaluation of dental pulp health is essential to avoid unnecessary endodontic treatments. In routine dental practice, pulp sensibility is commonly assessed using electric pulp testing and thermal (cold) testing.
- Trial name
- NCT07369297
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University