Clinical trials: HEALTHY INDIVIDUALS
Healthy
Effects of a Placebo Probiotic on Gut Health and General Well-being in Individuals With Mild Gastrointestinal Symptoms
The present study is aimed at exploring whether positive expectations of receiving a three-week treatment with a probiotic supplement (in fact a placebo) improve symptoms of gastrointestinal distress and promote physical and…
- Trial name
- PlaCIBO (NCT06720558)
- Testing
- Control-no treatment
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Breast Cancer
The Perspective of Healthy Individuals on Breast Cancer Risk Prediction Report In The Indonesian Population
In 2016, a meta-analysis showed that DNA-based risk reporting alone does not facilitate behavior change. However, there have been several studies showing that tailoring care plans related to diet may help with adherence to a…
- Trial name
- PERCEPTION (NCT05562440)
- Testing
- Focus Group Discussion
- Where
- Indonesia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Nalagenetics Pte Ltd
Comorbidities and Coexisting Conditions, Healthy
Immune Response of an Interchangeable Booster Vaccine Against COVID-19 Among Individuals With Risk Factors for Severity
Experimental, single-arm study in participants with comorbidities, previously immunized with 2 doses of CoronaVac, who will receive a booster vaccine with 1 dose of the Oxford/AstraZeneca vaccine.
- Trial name
- COVACManaus2 (NCT05289206)
- Testing
- Vaccine - ChAdOx1-S/nCoV-19 [recombinant]
- Where
- Brazil
- Volunteers
- 4,446 people, healthy volunteers welcome
- Sponsor
- Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
Depressive Disorder
Effects of Non-drug Therapy on Cognitive Function in Healthy Individuals and Patients With First Episode Depression
Mindfulness training, relaxation training, and cerebellar electrical stimulation were used to intervene in the cognitive function of healthy individuals and individuals with first episode depression
- Trial name
- NCT04503343
- Testing
- non-drug intervention
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Central South University
Tetanus, Tetanus Vaccine
Phase I/III Clinical Trial of Adsorbed Tetanus Vaccine
The study aimed to evaluate the safety and immunogenicity of an adsorbed tetanus vaccine in healthy individuals between 18 and 43 years of age.
- Trial name
- NCT07740733
- Testing
- Tetanus Toxoid (Adsorbed)
- Where
- China
- Volunteers
- 1,240 people, healthy volunteers welcome
- Sponsor
- Beijing Minhai Biotechnology Co., Ltd
Healthy Lifestyle
E-Health Literacy, Digital Literacy, Healthy Lifestyle and Web Based Education for Young Old Individuals
A healthy lifestyle is defined as knowing and controlling all the behaviors that may affect the health of the individual and regulating his daily activities by choosing the appropriate behaviors for his/her own health status.
- Trial name
- NCT06022185
- Testing
- Web Based Training on E-health Literacy, Digital Literacy and Healthy Lifestyle Behaviors.
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Igdir University
Hypertension
Attitudes and Understanding of Sodium Claims on Food Labels
Sodium-related claims on food labels should help people find lower sodium food choices; however consumer attitudes and understanding of such claims are unknown.
- Trial name
- NCT01764724
- Testing
- Mock package questionnaire
- Where
- Canada
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Individuals With Hamstring Tightness
The Immediate Effects Of Thoracolumbar Fascia Inhibition And Suboccipital Muscle Inhibition
This randomized controlled trial aimed to compare the immediate effects of two self-myofascial release techniques-suboccipital muscle inhibition and thoracolumbal fascia inhibition-on hamstring flexibility, spinal range of…
- Trial name
- NCT07096076
- Testing
- Thoracolumbar fascia inhibition, Suboccipital inhibition group, hamstring stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment
"Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients"
"This study aims to investigate ultrasonographic parameters of the median nerve in healthy individuals and patients with mild and moderate carpal tunnel syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment, Electrophysiologic Study, Ultrasound
- Trial name
- NCT07408596
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Emesis
The Antiemetic Effects of Increased Splanchnic Perfusion, Induced by the Gut Hormone GIP, in Healthy Individuals
This study investigates whether the gut hormone glucose-dependent insulinotropic polypeptide (GIP) can reduce feelings of nausea.
- Trial name
- GIP EMESIS (NCT07687589)
- Testing
- Glucose-dependent Insulinotropic Polypeptide (GIP), GLP-1 (7-36) amide, Apomorphine Injectable Solution
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy
Effect of B-GOS on the Wellbeing and Ageing in Healthy 52-65 Years Old Individuals
To investigate the potential of B-GOS to beneficially influence the wellbeing and ageing in healthy adults (52-65 years old). The study will consist of a 4 month randomised double blind parallel treatment period with either B-GOS…
- Trial name
- NCT02716350
- Testing
- B-GOS, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Clasado Limited
Healthy Adult
Exploring Pain Modulation With TMS and Repeated Pain Conditioning in Healthy Individuals
Conditioned pain modulation (CPM) is the behavioral measure of diffuse noxious inhibitory control (DNIC), an endogenous pain inhibitory pathway in which pain inhibits pain.
- Trial name
- NCT06726018
- Testing
- Conditioned Pain Modulation (CPM)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Priyanka Rana, PT, MPT, PhD
Effects of Walking and Cycling on Serum Physiological Biomarkers
Evaluation of Serum Autophagic Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Individuals
Physical exercise (walking and cycling) is a potent physiological stimulus that simultaneously alters energy balance, mechanical loading, and metabolic demands in the organism.
- Trial name
- NCT07536659
- Testing
- WALKİNG
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Romano-Ward Syndrome, Long QT Syndrome
Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features in Long QT Romano-Ward Syndrome Patients.
The objectives of the study are to investigate if KCNQ1 mutation in Romano-Ward long QT patients can be associated with changes in insulin regulation and with psychological features of compulsivity, impulsivity and behavioural…
- Conditions
- Romano-Ward Syndrome, Long QT Syndrome, Compulsive Behavior, Healthy Individuals
- Trial name
- PRIME (NCT04715256)
- Testing
- Cognitive assessment of obsessive-compulsive and impulsive behaviours, Genomic analysis, Glucoregulation assessment
- Where
- 2 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biotrial
Heart Failure Risk Factors in Healthy Individuals
Cleveland Heart and Metabolic Prevention Study
The purpose of this research study is to investigate the role of chemical reactions, such as inflammation and oxidation, in the cause of cardiac dysfunction (the heart does not function properly).
- Trial name
- CHAMPS (NCT03012022)
- Where
- United States
- Volunteers
- 1,208 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Healthy Subjects
A Trial to Determine How Long Insulin and FDKP (the Molecule That Forms Technosphere Particles) Stays in the Lungs of Healthy Individuals After Inhalation of Technosphere® Insulin (TI) Powder Using Bronchoalveolar Lavage (BAL)
Lavage fluid (BAL) is inserted into a lung lobe using a flexible bronchoscope. The fluid is aspirated out to remove any remaining TI. It's performed twice at specific time points in 12 healthy volunteers.
- Trial name
- NCT00757367
- Testing
- TI Inhalation Powder
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Obesity, Morbid Obesity
Effects of RM-493 on Energy Expenditure in Obese Individuals
Background: RM-493 is a drug that stimulates parts of the brain that control eating and metabolism. It has helped to reduce body weight and improve insulin sensitivity in lab tests.
- Trial name
- NCT01867437
- Testing
- RM-493
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Schizophrenia; Psychosis
Uppsala Psychosis Cohort
A multimodal longitudinal study in early stage psychosis patients and individuals at high risk for psychosis. Healthy controls are included for baseline comparisons.
- Trial name
- UPC (NCT05763966)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Postprandial Hyperglycemia, Lipidemia
Black Rice Anthocyanin in Mixed Meals: Influence on Postprandial Glycaemic and Lipid Responses Among Healthy Individuals
The diabetes epidemic is a pertinent concern globally. The prevalence of this metabolic disease among adults had been disclosed by the World health Organisation (WHO), reporting a total of 422 million diabetic adults and 3.7…
- Trial name
- NCT04063137
- Testing
- Anthocyanin fortified bread with beef patty (35% fat)
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Healthy
Quadriceps Concentric vs Eccentric
The aim of the study is to compare the effects of concentric and eccentric exercises on muscle strength, muscle thickness and balance in healthy Individuals.
- Trial name
- NCT03636854
- Testing
- Concentric exercises, Eccentric exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University