Clinical trials: HEALTHY INDIVIDUALS
Glucocorticoids, Obesity and Overweight
Acute Effects of Ultra-processed Versus Unprocessed Foods on Glucocorticoid Secretion in Healthy Individuals
The investigators aim to understand whether the acute cortisol response to food differs between differently processed foods. In this monocentric, randomized, cross-over, open-label study, 20 healthy volunteers will receive two…
- Conditions
- Glucocorticoids, Obesity and Overweight, Food Effect
- Trial name
- UltraCort (NCT06724692)
- Testing
- Ultra-processed breakfast, Low-processed breakfast
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eleonora Seelig
Hypoxia, Mental Disorder
Going to Altitude With Anxious-depressive Symptoms
Introduction: Currently, there is a lack of international guidelines or clinical recommendations for individuals with mental illnesses (i.e., bipolar disorder, posttraumatic stress disorder) going on high altitude sojourns.
- Trial name
- Psychoxie (NCT05323864)
- Testing
- Hypoxia
- Where
- Austria
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universitaet Innsbruck
Young, Healthy
Videofluoroscopic of Deglutition Study of the Initiation of Pharyngeal Phase in Young Adults
This study has as objective to characterize the start of pharyngeal phase of swallowing, in the various food consistencies and volumes, with and without the influence of verbal orders, observed on videofluoroscopy of deglutition.
- Trial name
- VFD-IPP (NCT01120587)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fortaleza University
Healthy, Activity, Motor
The Effect Of Transcutaneous Auricular Vagus Nerve Stimulation On Sports Performance And Physiological Parameters
OBJECTIVE: The aim of this study is to investigate the effect of non-invasive auricular VNS (Vagus Nerve Stimulation) on sportive performance and physiological parameters in healthy individuals.
- Trial name
- VNS001 (NCT04768738)
- Testing
- Auricular Vagus Nerve Stimulation Level Of Above Threshold, Auricular Vagus Nerve Stimulation Level Of Subthreshold, 5 Minutes Bicycle Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Sinop University
Type 2 Diabetes, Diabetes
The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers
This study, conducted at the Phoenix Indian Medical Center, Phoenix, Arizona, will determine whether reducing subclinical inflammation lessens insulin resistance in healthy, obese volunteers.
- Trial name
- NCT00339833
- Testing
- Salsalate
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diaphragm Fatigue, Healthy
Inspiratory Resistive Loading and Diaphragm Fatigue
The aim of the study is to clarify whether specific loading of the inspiratory muscles induces contractile fatigue of the diaphragm muscle in healthy individuals and individuals with recurrent low back pain.
- Conditions
- Diaphragm Fatigue, Healthy, Low Back Pain
- Trial name
- NCT01505517
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy, Healthy Adult
Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on sleeping parameters by polygraphy in healthy individuals, who live permanently >2600m.
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07801950
- Testing
- Descent from 2850m to sea level and re-ascent back to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Healthy Individuals (Controls), Vascular Surgery Patients With Acute Thrombosis
Haemodialysis Alters Hypercoagulability of Blood in Dialysis Patients
Primary Objective: To develop a thrombotic event risk assessment model integrating serum biomarkers (TM, TAT, t-PAIC, PIC) with clinical data, systematically compare its predictive performance across healthy populations, vascular…
- Conditions
- Healthy Individuals (Controls), Vascular Surgery Patients With Acute Thrombosis, Dialysis Patients
- Trial name
- TAT-t-PAIC (NCT07098676)
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Ai Peng
Healthy Individuals (Clinicians)
Do Clinicians Want Recommendations?
The use of the best evidence available for decision-making is nowadays an undisputed goal in health care. However, this is not always achieved in the context of clinical practice.
- Trial name
- NCT02006017
- Testing
- Evidence summary alone plus a recommendation, Evidence summary alone
- Where
- Canada
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- McMaster University
Smartphone Addiction, Postural; Defect
Smartphone & Headphone Effects on Baropodometric Parameters
The goal of this observational study is to observe baropodometric parameters such as postural sway and foot pressure distrubiton in healthy young participants between the ages of 18-35.
- Conditions
- Smartphone Addiction, Postural; Defect, Dual Task
- Trial name
- NCT06400576
- Testing
- Headphone and Smartphone Intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Subjects
Neurophysiologic Effects of Cervical Spinal Manipulation in Asymptomatic Individuals
This study had the goal of analyse the neurophysiologic effects of both mechanical and manual cervical manipulation, in asymptomatic individuals.
- Trial name
- NCT03463343
- Testing
- Cervical spine manual manipulation, Cervical spine mechanical manipulation
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
CRPS
Complex Regional Pain Syndrome (CRPS) and the Gut-bacteria
The purpose of this study is to investigate, for the first time, whether gut bacteria composition and function of patients with CRPS differ from those of healthy adults.
- Trial name
- NCT05473338
- Testing
- Stool and blood samples, Physical examination, Questionnaires
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Shoulder Pain, Healthy Volunteers
Sensory Processing and Musculoskeletal Shoulder Pain
The development of chronic pain is a common complication in shoulder pain conditions. Half of these type of patients exhibit persistent pain even after a period of six to twelve months from the start of their pain treatment.
- Trial name
- NCT05368649
- Testing
- Short-wave diathermy
- Where
- Argentina
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Flexibility, Hamstring Muscles
Effects of Different Electrophysical Agents in Hamstring Muscles Flexibility of Healthy Individuals
Sixty healthy individuals will be randomised into four groups. Group I (15 subjects) will be applied hotpacks, Group II (15 subjects) will be applied infrared, Group III will be applied ultrasound to hamstring muscles for 18…
- Trial name
- NCT04328155
- Testing
- Hotpack Group, Infrared Group, Ultrasound Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Healthy, Sports Physical Therapy
The Effect of Vagus Nerve Stimulation on Cycling Ergometry and Recovery
It is aIt is aimed to examine the possible benefits and effects of the use of Transcutaneous Auricular Vagus Nerve Stimulation to be applied in healthy individuals for sportive purposes on recovery and sportive performance level.
- Conditions
- Healthy, Sports Physical Therapy, Activity, Motor
- Trial name
- TAVNSCER (NCT05778058)
- Testing
- Unilateral Stimulation, Bilateral Stimulation, Bicycle Ergometer Test
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sinop University
Dietary Supplementation
Effects of Acute Grape Seed Extract Supplementation on Muscle Metaboreflex in Healthy Young Individuals
The aim of this study was to determine whether grape seed extract (GSE) supplementation could reduce the blood pressure (BP) in response to static exercise and post exercise muscular ischemia (PEMI) in normotensive young adults.
- Trial name
- NCT05945771
- Testing
- Grape seed extract
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Baptist University
Hyperglycemia, Postprandial
Effect of Salba & Flax on Postprandial Glycemia and Subjective Satiety
The purpose of this study is to determine whether drinks containing Salvia hispanica L (Salba) or Flax lower postprandial blood glucose levels and improve appetite in healthy individuals.
- Trial name
- NCT02621307
- Testing
- Salba, Flax, Control
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Essential Tremor, Healthy Individuals
Impact of Sensory Electrical Stimulation on Sensation and Tremor
The purpose of this study is to understand the acute, short-term and long-term impact of transcutaneous and/or percutaneous electrical stimulation with afferent-specific electrical stimulation (asES) on proprioception and fine…
- Trial name
- NCT06428526
- Testing
- Continuous stimulation strategy, Closed-loop stimulation strategy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Alzheimer Disease, Early Onset
The Resting-state EEG Gamma Oscillations in Alzheimer's Disease
The literature suggests a strong association between amyloid accumulation and gamma alterations, emerging gamma activity as a biomarker candidate for Alzheimer's pathology.
- Trial name
- EEG (NCT05989087)
- Testing
- CSF
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Görsev Yener, MD, PhD
Healthy
The Effects of Dark Chocolate (70% Cacao) on EEG Brain Waves in Vigorously Active Individuals
The purpose of this graduate student study is to determine if ingestion of dark chocolate (70% cacao) will change brain frequencies between visualization at a state of rest and a state of exercise performance via…
- Trial name
- NCT03203824
- Testing
- dark chocolate, non dark chocolate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Loma Linda University