Clinical trials: HEALTHY INDIVIDUALS
Pharmacokinetics, Epinephrine
Study of Drug Exposure in Systemic Circulation of Primatene Mist by Oral Inhalation, Versus Epinephrine Injection by Intramuscular Injection and ProAir by Oral Inhalation in Healthy Individuals
To assess the drug exposure profile in systemic circulation of Primatene Mist by inhalation, versus Epinephrine by intramuscular injection, and ProAir HFA by inhalation in healthy adults.
- Conditions
- Pharmacokinetics, Epinephrine, Albuterol, Asthma
- Trial name
- NCT04207840
- Testing
- Epinephrine (0.125 mg/inhalation), Epinephrine Injection Auto-Injector (0.3mg/0.3mL), Albuterol Sulfate (0.09 mg/inhalation)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Cervical Proprioceptive Error in Healthy Young Individuals
Proprioceptive Puzzle: Effects on Quantitative Sensory Tests and Body Awareness
Background: Cervical proprioception, referring to the awareness of the head's position in space, plays a crucial role in maintaining postural control and preventing musculoskeletal injuries.
- Trial name
- NCT06559397
- Testing
- Assessment of cervical proprioception
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nagihan Acet
Instrument-assisted Soft Tissue Mobilization, Flexibility
Investigation of the Effect of Instrument-Assisted Soft Tissue Mobilization Technique on Flexibility and Thickness by Compression Elastography Method in Healthy Individuals.
Instrument-assisted soft tissue mobilization is an instrument-assisted soft tissue mobilization technique. It consists of stainless steel instrument designed to adapt to various tissues/shapes/curves of the body.
- Conditions
- Instrument-assisted Soft Tissue Mobilization, Flexibility, Thickness, Compression Elastography
- Trial name
- NCT05503615
- Testing
- Observational, IASTM Technique Application
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Inonu University
Healthy
A Parallel Study Evaluating the Safety of Lactospore® in Healthy Individuals
The purpose of this study is to determine whether Lactospore is safe in healthy adults.
- Trial name
- 14PSHS (NCT02176889)
- Testing
- Lactospore
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Stroke, Healthy Volunteers
Effects of Rehabilitation Robots-Morning Walk in Individuals With Hemiparesis
In this study, our objective is to explore and evaluate interventions to improve the process of recovery following a stroke. The main focus is on enhancing symmetrical walking patterns in adults who have experienced neurological…
- Trial name
- NCT06374706
- Testing
- Morning Walk training for stroke, Morning Walk training for healthy
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Healthy Participants, Obese But Otherwise Healthy Participants
Fructose Intestinal Gluconeogenesis
This study will test the hypothesis that within a defined range of fructose intake, the ability to convert fructose to glucose (via gluconeogenesis) in the small intestine plays a protective role for the liver, shielding it from…
- Trial name
- FIG (NCT07209202)
- Testing
- High fructose meal, Low fructose meal, 13C labeled fructose, oral
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Touro University, California
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Sports Physical Therapy
Smartphone Addiction and Physical Activity
This study aimed to determine the effect of smartphone addiction on physical activity level in healthy individuals. A total of 300 (134 female) healthy university students were included in this study.
- Trial name
- NCT04299074
- Testing
- addiction
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
The Impact of American Ginseng on the Metabolomics of Urine and Plasma in Healthy Individuals
LCMS-Based Metabolic Analysis Explores the Effect of American Ginseng on Urine and Plasma in Healthy Individuals
Researchers will use LCMS Metabolic Analysis to Explore the Effect of American Ginseng on Urine and Plasma in Healthy Individuals Participants will: Take 3 grams of American Ginseng powder every day for 14 days Collect the…
- Trial name
- NCT07252362
- Testing
- American Gginseng
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zhejiang Cancer Hospital
Uric Acid, Cardiovascular Diseases
Acute Effects of Tart Cherry on Uric Acid and Biomarkers of CVD Risk in Healthy Individuals
This study aims to provide evidence as to whether consumption of tart cherry juice can reduce the risk of gout and cardiovascular disease (CVD) in an acute context.
- Conditions
- Uric Acid, Cardiovascular Diseases, Gout
- Trial name
- NCT04960527
- Testing
- Tart cherry juice, Water
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Hyperkyphosis, Viscoelasticity
Viscous Elastic Properties of Superficial Back Muscles in Individuals With Hyperkyphosis
Thoracic hyperkyphosis is a common spinal deformity that may alter the biomechanical and viscoelastic properties of trunk muscles.
- Trial name
- NCT07441213
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Sanko University
Healthy
A Novel Smartphone Application for "Smart" Trials
The overarching goal is to develop a mHealth App that can use smartphone embedded sensors to objectively collect physical function data in healthy individuals in the context of daily life.
- Trial name
- NCT04052282
- Testing
- Mobile Health App
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Elderly People
Improving the Quality of Life of Elderly Individuals Living in Nursing Homes
The development of physical activity (PA) and exercise habits improves strength, flexibility, balance and coordination, activities such as walking, sleep quality and cognitive status in elderly people and supports their…
- Trial name
- NCT06520956
- Testing
- Video based exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
Sars-CoV-2 Infection
Safety, Tolerability and Immunogenicity of Alveavax-v1.2, a BA.2/Omicron-optimized, DNA Vaccine for COVID-19 Prevention
The investigated product is a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Booster Vaccine candidate optimized for the Omicron/BA.2 variant.
- Trial name
- NCT05844202
- Testing
- Alveavax-v1.2, Janssen Ad26.COV2.S
- Where
- 8 sites in South Africa
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Alvea Holdings, LLC
High Altitude, Six-minute Walk Test
Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of descent from high altitude (Quito Ecuador: 2850m) to sea level on six-minute walking distance and scores in healthy individuals, who live permanently >2600m.
- Conditions
- High Altitude, Six-minute Walk Test, High Altitude Effects, Healthy
- Trial name
- NCT07801872
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Protein Requirement of Athletes
Measuring Protein Requirement Using Amino Acid Oxidation in Strength and Endurance Athletes
Our objective is to determine the dietary requirement of protein for strength and endurance exercise trained (more than 4 months training experience) individuals between 18 - 30 years of age using the indicator amino acid…
- Trial name
- NCT02621294
- Testing
- Measuring protein requirement
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Cardiovascular Diseases
Effect of Flax, Poppy, Sesame & Salba on Postprandial Blood Glucose Response, Vascular, Appetite & Sensory Parameters
Consumption of whole grains has been heavily endorsed by both government and major health agencies, as evidenced in Health Canada's Food Guide, the US Department of Agriculture's Food Pyramid, and the Heart and Stroke…
- Trial name
- NCT01579656
- Testing
- Salba, Poppy, Flaxseed
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Thumb Manipulation, Hand Grip Strength
Effects of Thumb Manipulation on Hand Grip Strength, Function, and Sensation
This randomized controlled study will aim to investigate the effects of thumb manipulation on hand grip strength, function, and sensation in healthy individuals.
- Conditions
- Thumb Manipulation, Hand Grip Strength, Hand Sensory Function, Hand Function in Healthy Individuals
- Trial name
- THUMBFUN (NCT07068698)
- Testing
- Thumb Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Healthy
Oxytocin Effect on Attentional Bias Towards Emotional Expression Faces in Individuals With High and Low Autistic Traits: A Functional Magnetic Resonance Imaging (fMRI) Study
to investigate whether oxytocin alter attentional bias towards emotional expression faces in individuals with high and low autistic traits, and the brain mechanism of this effect
- Trial name
- NCT02741063
- Testing
- screen low autistic subjects, screen high autistic subjects, oxytocin
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Healthy, Physical Activity
Virtual Reality Exergaming on Heart Rate, Perceived Exertion, and Technology Acceptance in Healthy Individuals
This pilot cohort study aimed to investigate the immediate impact of Virtual Reality (VR) exergaming on heart rate (HR), rate of perceived exertion (RPE), and technology acceptance using the Unified Theory of Acceptance and Use…
- Conditions
- Healthy, Physical Activity, Virtual Reality, Exergame
- Trial name
- NCT06411119
- Testing
- Meta Oculus Quest 2™ Virtual Reality Exergaming
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Teesside University