Clinical trials: HEALTHY INDIVIDUALS
Healthy
Transcranial Focused Ultrasound (tFUS) Modulation of Reward Network
Aim: Evaluate whether sonicating the Nucleus Accumbens (NAc) with transcranial focused ultrasound modifies functional connectivity between the NAc and the prefrontal cortex (PFC).
- Trial name
- NCT05986019
- Testing
- transcranial focused ultrasound (tFUS)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Fatty Acids, Omega-3, Fish Oils
Metabolic Impact of VLCPUFA-Rich Fish Oil: A Clinical Study on Omega-3 Index Enhancement in Healthy Individuals
Background: Fish oils contain omega-3 fatty acids that play important roles in the body. Researchers are studying a new type of fish oil that contains very-long-chain omega-3 fatty acids (VLCPUFAs).
- Trial name
- NCT07882160
- Testing
- VLCPUFA-rich fish oil, DHA-rich fish oil
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy Individuals, Patients With Arm Pump
Arm Pump in Motorcross Training
Arm Pump is a sport specific term drivers use to describe Acute or Chronic Compartment Syndrome of the forearm. Drivers experience pain in the forearms due to increased blood pressure in forearm muscle compartments.
- Trial name
- NCT02096796
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy Individuals
Impact Of Aerobic Exercise on Sleep Quality and Postural Control Interplay Among University Students
The purpose of this study is to investigate the impact of moderate-intensity aerobic treadmill exercise on sleep quality and postural control interplay among university students with poor sleep quality.
- Trial name
- NCT07909980
- Testing
- Aerobic exercise Training, Sleep hygiene education
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Cerebellar Ataxia, Healthy Adults
Circular Timed Up and Go (cTUG) for Ataxia: Development and Validation
Cerebellar ataxia (CA) is a collection of signs and symptoms caused by cerebellar dysfunction, which can be the result of different disease processes including hereditary and acquired conditions.
- Trial name
- cTUG (NCT05132647)
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Healthy
A Study of Heterologous Vaccine Regimen of Adenovirus Serotype 26 Mosaic4 Human Immunodeficiency Virus(Ad26.Mos4.HIV), Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals Who Have Sex With Cis-gender Men and/or Transgender Individuals
The purpose of this study is to evaluate the vaccine efficacy (VE) of a heterologous vaccine regimen utilizing Ad26.Mos4.HIV and aluminum phosphate-adjuvanted Clade C gp140 and Mosaic gp140 for the prevention of HIV-1 infection…
- Trial name
- MOSAICO (NCT03964415)
- Testing
- Ad26.Mos4.HIV, Clade C and Mosaic gp140 HIV bivalent vaccine
- Where
- 53 sites in United States, Argentina and 7 more
- Volunteers
- 3,900 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Healthy
Effects of Ethanol on Intestinal Permeability and Integrity
Alcohol consumption is a major health problem worldwide. It affects all systems of the body especially the gastrointestinal tract.
- Trial name
- NCT00928733
- Testing
- Gastroduodenoscopy- Intraduodenal intubation
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Muscle Soreness, Stiffness of Elbow, Not Elsewhere Classified
The Role of Manual Twirling Acupuncture in Reducing Muscle Pain and Stiffness After Biceps Curling in Healthy Untrained Individuals
Regular physical activity can help to prevent and control non-communicable disease. WHO recommends at least in adults to do moderate-vigorous physical activity includes muscle strengthening.
- Trial name
- NCT06366555
- Testing
- Manual Acupuncture Twirling,
- Where
- Indonesia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Healthy
Adaptation in Polyphenol Bioavailability and Bioactivity During Long Term Exposure to Polyphenol-Rich Foods
There are two primary objectives to be addressed in this study: to assess the differential response in bioavailability and metabolic pathways between lean and obese individuals exposed to acute, short term (14 day), and long-term…
- Trial name
- NCT02197754
- Testing
- Controlled diet
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- USDA Beltsville Human Nutrition Research Center
Healthy Lifestyle, Education
Effects of Education After Colorectal Cancer Screening
The aim of this study is to examine the effect of the education given to individuals undergoing colorectal cancer screening on their attitudes, beliefs and healthy lifestyle behaviors.
- Trial name
- NCT06311565
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Aging
Participatory Evaluation (of) Aging (With) Rapamycin (for) Longevity Study
This is a randomized, placebo-controlled trial into the safety and efficacy in reducing clinical measures of aging in an older adult population.
- Trial name
- PEARL (NCT04488601)
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- AgelessRx
Muscle Weakness
Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness
The goal of this trial was to determine if a mid-thoracic high velocity low amplitude spinal manipulation improves force output in those with unilateral hip adductor weakness.
- Trial name
- NCT06534931
- Testing
- High velocity low amplitude thoracic spine manipulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New England
Kinesio Taping, Muscle Oxygenation
The Effect of Kinesio Taping Applied to the Gastrocnemius Muscle on Muscle Oxygenation, Pain Pressure Threshold, and Muscle Mechanical Properties
The aim of this study is to investigate the effects of kinesio taping applied to the gastrocnemius muscle on muscle oxygenation, pain pressure threshold, and mechanical properties of the muscle in healthy young individuals.
- Trial name
- NCT07572201
- Testing
- Kinesio® tape application
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Okan University
Elderly People
Improving the Quality of Life of Elderly Individuals Living in Nursing Homes
The development of physical activity (PA) and exercise habits improves strength, flexibility, balance and coordination, activities such as walking, sleep quality and cognitive status in elderly people and supports their…
- Trial name
- NCT06520956
- Testing
- Video based exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
Venous Sinus Thrombosis, Cranial
Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals
The anatomical characteristics of veins and venous sinus result in great differences between cerebral venous system diseases and cerebral artery diseases in etiology, pathophysiology and clinical features.Therefore, understanding…
- Trial name
- NCT05413837
- Testing
- anotomy and variation of venous sinus, the level of biomarker in bood
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Healthy Volunteers, Insulin Resistance
Polyphenols and Insulin Resistance
Diet and nutrition play an essential role in the development and the clinical expression of the most common health problems. Overeating and obesity induce oxidative stress, which has been proposed to be a pathogenic mechanism…
- Conditions
- Healthy Volunteers, Insulin Resistance, Type 2 Diabetes (T2D)
- Trial name
- POLYOXRESIST (NCT01478841)
- Testing
- polyphenol
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Healthy Individuals
Drug Use and Ultra-endurance Race
Hypothesis: To verify whether the use of drugs, in particular performance-enhancing drugs, is prevalent amongst participants in a very long distance mountain trail.
- Trial name
- Ultra-Trail (NCT03402022)
- Where
- France
- Volunteers
- 2,923 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy Individuals
Ascending Glycan Dietary Supplementation in Healthy Adults
The investigators will conduct a parallel-group, placebo-controlled, randomized, double-blind ascending dose Phase I study of dietary supplementation in healthy individuals to evaluate safety and to determine the…
- Trial name
- NCT04466761
- Testing
- Monosaccharide Powder
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity
Alpha and Omega of Lifestyle Therapy
The study aims to investigate the effects of double-blinded, randomized placebo-controlled n3-fatty acid supplementation (1000 mg day-1) and 13 weeks of resistance training on muscle function/biology and systemic health in…
- Trial name
- Alpha&Omega (NCT04279951)
- Testing
- Resistance exercise, Omega-3
- Where
- Norway
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Healthy
Synbiotic Approach to Immunity and Metabolism in the Elderly Study
The aging process leads to a marked decline in immune function (immunosenescence), causing a significant reduction in immune response after vaccination or infections.
- Trial name
- SAIMES (NCT03168503)
- Testing
- LGG+Promitor™, Promitor™, LGG-PB12+Promitor™
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Roehampton