Clinical trials: HEALTHY VOLUNTEERS
Healthy
Comparative Safety Study of New Sinecort Formulation Versus Positive Control
The study is focused to prove a favorable safety profile of the new formulation.
- Trial name
- NCT00885937
- Testing
- Dexpanthenol (Sinecort, BAY81-2996), Positive control, Na-laurylsulfat-solution, Untreated skin under application chamber
- Where
- Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
Drug-Drug Interaction Study With Metformin and Nizatidine
This study will address the following question: Does nizatidine affect the pharmacokinetics of metformin in healthy volunteers? Recent studies in the Giacomini laboratory have indicated that nizatidine may block metformin…
- Trial name
- NCT01409395
- Testing
- Metformin and nizatidine, Metformin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Single and Multiple Ascending Dose, First-in- Human Study in Healthy Subjects
This is a Phase 1, randomized, double-blinded, placebo controlled study. The study consists of 2 parts: Part A is a single ascending dose (SAD) study in healthy subjects and Part B is a multiple ascending dose (MAD) study in…
- Trial name
- NCT04044339
- Testing
- TD-5202
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Healthy Volunteers
A Study of How the Body Breaks Down and Eliminates LY2623091
This type of study is called a radiolabeled study. For this study, LY2623091 (study drug) has been specially prepared to contain radiolabeled carbon [^14C]. [^14C] is a naturally occurring radioactive form of the element, carbon.
- Trial name
- NCT02242981
- Testing
- LY2623091
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy Volunteers
Drug-Drug Interaction Study to Evaluate the Effect of PF-06865571 on Metformin Pharmacokinetics
This study is designed to assess the effect of PF-06865571 administration on the pharmacokinetics of metformin in healthy adult subjects.
- Trial name
- NCT03593707
- Testing
- Metformin, PF-06865571
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer
Retention, Urinary
Investigation of New Intermittent Catheters in Healthy Volunteers
Investigation of non-CE marked intermittent catheters. The study was a randomized, single blinded, cross-over investigation comparing two new catheters with a comparator catheter in 30 adult healthy volunteers.
- Trial name
- NCT04445051
- Testing
- SpeediCath® Standard male or female, New intermittent Variant 1 catheter for male or female, New intermittent Variant 2 catheter for male or female
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Healthy
Bioequivalence Trial of Concor AM® vs Bisoprolol and Amlodipine in Chinese Participants
This is a Phase I, open-label, randomized, 2-period, 2-sequence, crossover study to demonstrate bioequivalence (BE) between the bisoprolol-amlodipine fixed-dose-combination (FDC) tablet (investigational product) and bisoprolol…
- Trial name
- NCT03226275
- Testing
- Bisoprolol-Amlodipine FDC, Bisoprolol, Amlodipine
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Cholesterol Health
A Study to Evaluate the Effects of a Turmeric and Black Cumin Seed Formulation on Cholesterol Levels
The purpose of this study is to assess the effects of a turmeric and black cumin seed formulation on cholesterol levels.
- Trial name
- NCT03175757
- Testing
- Turmeric and Black Cumin Seed
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Infection, Human Immunodeficiency Virus
Absolute Bioavailability of BMS-626529 After Oral and Intravenous Dosing
A phase I absolute bioavailability study of BMS-626529 following oral and intravenous dosing
- Trial name
- NCT02805556
- Testing
- BMS-663068, BMS-626529
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Healthy Volunteers
A Study to Determine the Bioavailability of Various Formulations of GDC-0134 in Healthy Female Participants of Non-Childbearing Potential
This is a two-part study to determine the relative bioavailability of two different prototype capsules of GDC-0134 to that of an existing reference capsule of GDC-0134 under both fed and fasted conditions.
- Trial name
- NCT03807739
- Testing
- GDC-0134 F09 Formulation, GDC-0134 F15 Formulation, GDC-0134 F16 Formulation
- Where
- 2 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Healthy Volunteers
A Study of Marstacimab to Compare Prefilled Pen (PFP) Device to Prefilled Syringe (PFS) Device
The goal in this study is to show that there are not significant differences in biologic activity of the study drug when administered using either the prefilled pen and prefilled syringe.
- Trial name
- NCT04832139
- Testing
- Marstacimab PFP, Marstacimab PFS
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Pfizer
PK in Healthy Volunteers
Fexinidazole (1200mg) Bioavailability Under Different Food Intake Conditions
The present study is designed to assess the impact of concomitant food intake on the relative bioavailability of a single oral fexinidazole tablet administration.
- Trial name
- NCT01340157
- Testing
- Fexinidazole
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Drugs for Neglected Diseases
Anthrax, Anthrax Immunisation
Anthrax AV7909 Liquid vs Lyophilized
This is a randomized, parallel-group, double-blind, Phase 1 study designed to assess safety, tolerability and immunogenicity 2 formulations of adjuvanted anthrax vaccine (AV7909), lyophilized and liquid.
- Trial name
- NCT04660201
- Testing
- AV7909
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Platelet Function Test
Effect of Herbal Products on Platelet Function and Clotting
This is a research study on the effect of some commonly used "blood activating" herbal products on platelet function and coagulation profile, ie whether it causes an increase in bleeding tendency, either used alone or in…
- Trial name
- NCT02008981
- Testing
- Curcuma longa, Angelica sinensis, Siwu Tang
- Where
- Singapore
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Alzheimer's Disease
Brain Imaging Study in Subjects With Alzheimer Disease in Comparison to Healthy Subjects
The underlying goal of this study is to assess 123-I MNI-168 SPECT imaging as a tool to detect ß-amyloid deposition in the brain of Alzheimer's Disease (AD) research participants and similarly aged and gender matched healthy…
- Trial name
- NCT00870519
- Testing
- I-123-MNI-168, 123-I MNI-168
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Healthy Volunteers
A Study of Intravenously or Subcutaneously Administered REGN3500 in Healthy Adult Subjects
The primary objective of this study is to evaluate the safety and tolerability of single ascending intravenous (IV) and subcutaneous (SC) doses of REGN3500 in healthy adult males and females
- Trial name
- NCT02958436
- Testing
- REGN3500
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Healthy
Pivotal Bioequivalence Study of Topically Delivered Halobetasol Propionate Ointment in Normal Skin in Healthy Adult Subjects
The purpose of this study is to compare the vasoconstriction response profile and bioequivalence between one innovator lot of Ultravate® 0.05% ointment and one test/generic lot of Halobetasol propionate 0.05% ointment (Alpharma…
- Trial name
- NCT00865605
- Testing
- Halobetasol Propionate 0.05% Ointment, single exposure, Ultravate® 0.05% ointment, single exposure
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Hemorrhagic Fever, Ebola, Healthy
Experimental Ebola Vaccine Trial
This study will test the safety of an experimental vaccine developed to protect against Ebola virus infection and to determine if the vaccine induces an immune response to the virus.
- Trial name
- NCT00072605
- Testing
- VRC-EBODNA012-00-VP
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of JNJ-64991524 in Healthy Participants
The purpose of this study is to evaluate safety and tolerability of JNJ-64991524 compared with placebo after administration of single ascending oral doses of JNJ-64991524 (Part 1) and multiple ascending oral doses of JNJ-64991524…
- Trial name
- NCT03346122
- Testing
- JNJ-64991524 Dose Level 1, JNJ-64991524 Dose Level 2, JNJ-64991524 Dose Level 3
- Where
- Belgium
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy Volunteers
A Study to Assess the Relative Biological Availability and the Effect of Food on the Drug Levels of Danicamtiv in Healthy Adult Participants
The purpose of this study is to assess the relative biological availability and the effect of food on the drug levels of Danicamtiv in health adults.
- Trial name
- NCT06027437
- Testing
- Danicamtiv
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
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