Clinical trials: HEMORRHOIDS
Hemorrhoids
Ligasure Versus Conventional Diathermy in Hemorrhoidectomy
comparison study in the treatment of hemorrhoid between ligasure device and the conventional diathermy
- Trial name
- NCT07878546
- Testing
- ligasure
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hemorrhoids, Anal Fissure and Fistula
Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia
Study Description: The goal of this clinical trial is to compare the duration of postoperative pain relief achieved with two different approaches to pudendal nerve block in patients undergoing elective perianal surgery.
- Conditions
- Hemorrhoids, Anal Fissure and Fistula, Perianal Abscess, Perianal Fistula
- Trial name
- NCT05990569
- Testing
- Ultrasound guided Pudendal nerve block
- Where
- Nepal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nepal Mediciti Hospital
Hemorrhoids
EnSeal Device Versus Ferguson Technique in Hemorrhoidectomy
This study will compare hemorrhoid surgery by comparing a sutureless heating device with the old standard hemorrhoid surgery. Patients will be followed closely for wound healing and satisfaction.
- Trial name
- NCT00853853
- Testing
- EnSeal Device, Ferguson Hemorrhoidectomy technique
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Steven Schechter, M.D.
Hemorrhoid Pain
Post Hemorrhoidectomy Anorectal Pain
This is a quality assurance trial to evaluate the effectiveness of guided breathing exercises on reducing the symptoms of hemorrhoidal disease in colorectal surgery patients.
- Trial name
- NCT03240185
- Testing
- deep breathing exercises
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
HEMORRHOIDS, Extracellular Matrix Alteration
Hemorrhoids and Metalloproteinases, Observational Study
An association between hemorrhoidal disease and matrix metalloproteinases (MMPs) has been described previously. MMPs regulate extracellular structural proteins and tissue remodeling.
- Trial name
- HeMe (NCT02358174)
- Testing
- Hemorrhoidectomy, blood sampling, tissue sampling
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
Hemorrhoids Second Degree, Hemorrhoids Third Degree
Randomized Trial :Hemorrhoidal Pedicle Ligation vs Laser vs Open Hemorrhoidectomy
The aim of this study is to compare three different modalities for treatment of symptomatic 2 ° to 3 ° haemorrhoids: open haemorrhoidectomy, intrahaemorrhoidal laser procedure and haemorrhoidal pedicle ligation.
- Trial name
- NCT03757728
- Testing
- Haemorrhoidectomy operations
- Where
- Lithuania
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Hemorrhoids
Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease
Haemorrhoids are vascular cushions in the anal canal that help in the control of stool. When inflamed they become pathological and may present with protrusion and bleeding.
- Trial name
- NCT02782455
- Testing
- Flavonoids, CDobi
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Services Hospital, Lahore
Hemorrhoids
Hemorrhoidectomy Only Versus Hemorrhoidectomy With Lateral Internal Sphincterotomy
The aim of this study was to access the comparison of pain and complications after hemorrhoidectomy with or without lateral sphincterotomy.
- Trial name
- NCT06588374
- Testing
- lateral internal sphincterotomy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemorrhoidectomy, Third Degree Hemorrhoids
Hemorrhoidectomy in Patients With Grade III and IV Disease:Harmonic Scalpel Compared With Conventional Technique
Hemorrhoidectomy is the treatment of choice for grade 3 and 4th degree hemorrhoids. Various surgical technique has been used to improve the outcome of the procedures performed in respect to operative time ,post operative pain and…
- Conditions
- Hemorrhoidectomy, Third Degree Hemorrhoids, Fourth Degree Hemorrhoids, Operative Time
- Trial name
- NCT03938714
- Testing
- Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Services Hospital, Lahore
Hemorrhoid Pain, Hemorrhoids
Topical Analgesia Post-Haemorrhoidectomy
Symptomatic haemorrhoids, or piles, have significant effects on quality of life. The treatment for advanced disease is surgical excision (haemorrhoidectomy) which is extremely effective.
- Trial name
- NCT04276298
- Testing
- Metronidazole cream, Metronidazole and Diltiazem cream, Metronidazole and Lidocaine cream
- Where
- New Zealand
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Hemorrhoids
Laser Hemorrhoidoplasty Versus Open Surgical Hemorrhoidectomy in Second and Third Degree Piles
The study aims to compare the pain , duration of intervention and long term outcomes of laser hemorrhoidoplasty versus open surgical hemorrhoidectomy
- Trial name
- NCT05770141
- Testing
- laser hemorrhoidoplasty, open surgical hemorrhoidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemorrhoids
The Use of Topical Anaesthetic in the Banding of Internal Haemorrhoids
The investigators' aim is to assess if they can complete a study measuring the effect of local anaesthetic gel (Instillagel) on reducing pain experienced by patients undergoing a common treatment for haemorrhoids (piles).
- Trial name
- TAB (NCT04031131)
- Testing
- Instillagel, KY Gel
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Julie Dawson
Puerperal Infection, Fever
Diet and Lifestyle Intervention Study in Postpartum Women in China
Previous studies have shown "Doing the month", a traditional practice for postpartum women in China and other Asian countries, may be associated with higher prevalence of postpartum problems.
- Conditions
- Puerperal Infection, Fever, Constipation, Hemorrhoids
- Trial name
- NCT01039051
- Testing
- Diet and Lifestyle Intervention in Chinese Postpartum Women
- Where
- 3 sites in China
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Cold Argon Plasma
Cold Argon Plasma (CAP) Application in the Wound Treatment After Open Hemorrhoidectomy
This is single-center, prospective, randomized study
- Trial name
- NCT03907306
- Testing
- Wound healing
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Hemorrhoids
Napoleon Trial: Optimal Treatment for Recurrent Haemorrhoidal Disease
Rationale: There is level I evidence in literature that the first management step of HD is basic treatment, including laxatives and high fibre dieti, ii.
- Trial name
- NCT04101773
- Testing
- RBL versus sutured mucopexy versus haemorrhoidectomy.
- Where
- 16 sites in Netherlands
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Hemorrhoids
Ultrasound-guided Sacral Erector Spinae Plane Block as a Sole Anesthetic Technique Versus Saddle Block in Hemorrhoidectomy
Study interventions: The patients will be randomized into two equal groups, Group A and Group B. Group A: Patients will receive an Ultrasound guided sacral erector spinae plane block (SESPB) Group B: Patients will receive Saddle…
- Trial name
- NCT06969274
- Testing
- Ultrasound guided sacral erector spinae plane block (SESPB), Saddle block.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hemorrhoids
Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy
Over the past decade, continuous wound infiltration systems have been introduced to treat a variety of post-surgical pain. These systems, commonly referred to pain pumps by patients, possess a catheter(s) attached to a reservoir…
- Trial name
- NCT01099605
- Testing
- placement of a continuous infusion pump, continuous infusion pump of bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Hemorrhoids, Internal
The Effect of Rubber Band Ligation in Bleeding Internal Hemorrhoids.
In this study, the researchers planned to compare the treatment results of patients undergoing rubber band ligation in addition to drug therapy in hemorrhagic internal hemorrhoids patients and those treated only with…
- Trial name
- NCT04290351
- Testing
- band ligation, oral 450 mg diosmin+50 mg hesperidin
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Hemorrhoids Grade I and II
Hemoclin Gel for the Treatment of Hemorrhoids
Post market, single arm, clinical investigation to assess safety and performance of the product.
- Trial name
- NCT05124379
- Testing
- Hemoclin Gel
- Where
- Poland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Karo Pharma AB
Hemorrhoids
Efficacy of Lidocaine Gel Enema After Endoscopic Hemorrhoid Band Ligation for Relief of Post Procedural Pain
This is a prospective study to assess the utility of Lidocaine Hydrochloride 2% gel enema (Hi-Tech Pharmacal Co., Inc.) in reducing post-procedural pain after endoscopic band ligation of internal hemorrhoids.
- Trial name
- NCT03797703
- Testing
- Lidocaine Hydrochloride 2% gel enema
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences